Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4-Fluoro-7-nitrobenzofurazan

NBD-F is a fluorescent derivatization reagent which is originally developed for amino acid analysis.

  • CAS Number: 29270-56-2
  • MF: C6H2FN3O3
  • MW: 183.097
  • Catalog: Dye Reagents
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 308.6±45.0 °C at 760 mmHg
  • Melting Point: 52-54 °C(lit.)
  • Flash Point: 140.4±28.7 °C

RNA splicing modulator 3

RNA splicing modulator 3 (compound 236) is a RNA splicing modulator, with an AC50 value of <100 nM[1].

  • CAS Number: 2726461-43-2
  • MF: C19H20N6OS
  • MW: 380.47
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diosmetin-7-O-beta-D-glucopyranoside

Diosmetin-7-O-β-D-glucopyranoside is a natural product isolated from the flowers of Chrysanthemum morifolium, with antioxidant activity[1][2].

  • CAS Number: 20126-59-4
  • MF: C22H22O11
  • MW: 462.404
  • Catalog: Others
  • Density: 1.609
  • Boiling Point: 803.6±65.0 °C at 760 mmHg
  • Melting Point: 253-255 ºC
  • Flash Point: 281.7±27.8 °C

Auramine O

Auramine O is a yellow fluorescent dye and can be used to stain acid-fast bacteria. Auramine O is toxic and resistant in the environment[1][2].

  • CAS Number: 2465-27-2
  • MF: C17H22ClN3
  • MW: 303.830
  • Catalog: Others
  • Density: 1.01g/cm3
  • Boiling Point: 406.2ºC at 760mmHg
  • Melting Point: >250 °C (dec.)(lit.)
  • Flash Point: 199.4ºC

1,3,6,8-Tetrahydroxynaphthalene

1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin[1].

  • CAS Number: 18512-30-6
  • MF: C10H8O4
  • MW: 192.16800
  • Catalog: Others
  • Density: 1.638g/cm3
  • Boiling Point: 407.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 208.9ºC

2,3-Dihydroheveaflavone

Podocarpus flavanone is a natural product that can be isolated from Podocarpus taxifolia[1].

  • CAS Number: 110382-42-8
  • MF: C33H26O10
  • MW: 582.55
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 846.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.8±27.8 °C

(S)-Boc-2-amino-5-azido-pentanoic acid dicyclohexylammonium

(S)-Boc-2-amino-5-azido-pentanoic acid (dicyclohexylammonium) is an amino acid derivative, can be used for the synthesis of compounds[1].

  • CAS Number: 1485528-98-0
  • MF: C22H41N5O4
  • MW: 439.59
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ciwujianoside A1

Ciwujianoside A1 is isolated from the Eleutherococcus senticosus leaf[1].

  • CAS Number: 120768-65-2
  • MF: C59H96O26
  • MW: 1221.391
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Endo-1,4-β-galactanase

Endo-1,4-β-galactanase is a glycoside hydrolase that catalyzes the hydrolysis of β-1,4 galactosidic bonds in arabinogalactan and galactan side chains found in type I rhamnogalacturan[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyprodinil-d5

Cyprodinil-d5is the deuterium labeledCyprodinil(HY-116214)[1]. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 μM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 μM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 μM)[2].

  • CAS Number: 1773496-67-5
  • MF: C14H10D5N3
  • MW: 230.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biguanidinium-porphyrin

Biguanidinium-porphyrin is a mitochondria-targeting photosensitizer. Biguanidinium-porphyrin distributes within cell membranes with a large component in vesicles that correlated to some extent with the lysosomes and, upon longer exposures, in mitochondria and the cytosolic membrane[1].

  • CAS Number: 1014978-87-0
  • MF: C46H36ClN9
  • MW: 750.29
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BTA-1

BTA-1 is an uncharged derivative of thioflavin-T. BTA-1 has high affinity for Aβ fibrils and shows very good brain entry and clearance[1].

  • CAS Number: 439858-28-3
  • MF: C14H12N2S
  • MW: 240.32300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Macrostemonoside I

Macrostemonoside I is a furostanol saponin that can be isolated from Allium macrostemon[1].

  • CAS Number: 162413-63-0
  • MF: C45H72O20
  • MW: 933.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N1,N3,N5-Tris[3-(didodecylamino)propyl]-1,3,5-benzenetricarboxamide

N1,N3,N5-Tris[3-(didodecylamino)propyl]-1,3,5-benzenetricarboxamide for the preparation of mRNA-delivered liposomal nanoparticles to improve in vitro transfection efficiency[1].

  • CAS Number: 1821214-50-9
  • MF: C90H174N6O3
  • MW: 1388.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride

(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 14328-62-2
  • MF: C8H16ClNO2
  • MW: 193.671
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 249.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 104.9ºC

BOC-GLY-OME

Boc-Gly-OMe is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 31954-27-5
  • MF: C8H15NO4
  • MW: 189.209
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 266.8±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 115.2±22.6 °C

2-Hydroxyoctadecanoic acid

DL-alpha-Hydroxystearic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 629-22-1
  • MF: C18H36O3
  • MW: 300.47700
  • Catalog: Others
  • Density: 0.944g/cm3
  • Boiling Point: 432.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 229.6ºC

p-Hydroxyhippuric Acid

4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding[1].

  • CAS Number: 2482-25-9
  • MF: C9H9NO4
  • MW: 195.17200
  • Catalog: Others
  • Density: 1.4g/cm3
  • Boiling Point: 516.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 266ºC

2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine

2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 433288-71-2
  • MF: C13H18N6O6
  • MW: 354.32
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 777.3±70.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 423.9±35.7 °C

MK2-IN-5

MK2-IN-5 is a Mk2 pseudosubstrate (Ki= 8 μM). MK2-IN-5 targets the protein interaction domain in the MAPK pathway. MK2-IN-5 inhibits HSP25 and HSP27 phosphorylation[1][2][3].

  • CAS Number: 474713-20-7
  • MF: C61H113N21O16
  • MW: 1396.68
  • Catalog: HSP
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Phe-Pip-Arg-pNA hydrochloride

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform[1][2].

  • CAS Number: 160192-34-7
  • MF: C27H37ClN8O5
  • MW: 589.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Oxo Ibuprofen

1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

  • CAS Number: 65813-55-0
  • MF: C13H16O3
  • MW: 220.26400
  • Catalog: Others
  • Density: 1.107g/cm3
  • Boiling Point: 377.952ºC at 760 mmHg
  • Melting Point: 85-87ºC
  • Flash Point: 196.555ºC

1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)

16:0-18:1 PS-d31 (sodium) is deuterium labeled 16:0-18:1 PS (sodium).

  • CAS Number: 327178-96-1
  • MF: C40H44D31NNaO10P
  • MW: 815.179
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Nitrobenzoic acid-d4

4-Nitrobenzoic acid-d4 is the deuterium labeled 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate  (Vonoprazan Impurity)[1].

  • CAS Number: 171777-66-5
  • MF: C7HD4NO4
  • MW: 171.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dibenzylamine-d10

Dibenzylamine-d10 is the deuterium labeled Dibenzylamine[1].

  • CAS Number: 923282-09-1
  • MF: C14H15N
  • MW: 197.27600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Valine-d8

L-Valine-d8 (L-VALINE-2,3,4,4,4,5,5,5-D8) is a stable-isotope label reagent, is use in the labelled synthesis of L-valineamide-d8 intermediate[1].

  • CAS Number: 35045-72-8
  • MF: C5H3D8NO2
  • MW: 125.20
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 213.6±23.0 °C at 760 mmHg
  • Melting Point: 295-300 ℃ (subl. )(lit.)
  • Flash Point: 83.0±22.6 °C

Proteinase

Proteinase refers to the enzymes which display proteolytic activity with potency value of 15100 U/g.

  • CAS Number: 9001-92-7
  • MF: C41H42N4O7Cl2Br+
  • MW: 853.604780000001
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-Ketoisohexanoic acid-d3 sodium

α-Ketoisohexanoic acid-d3 (sodium) is the deuterium labeled α-Ketoisohexanoic acid sodium[1].

  • CAS Number: 172330-01-7
  • MF: C6H7D3NaO3
  • MW: 156.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Thr-OH

Fmoc-Thr-OH is a threonine derivative[1].

  • CAS Number: 73731-37-0
  • MF: C19H19NO5
  • MW: 341.358
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 596.5±50.0 °C at 760 mmHg
  • Melting Point: 115°C (dec.)
  • Flash Point: 314.6±30.1 °C

H-Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe trifluoroacetate salt

H-Leu-Ser-Phe(NO2)-Nle-Ala-OMe TFA is a substrate for chymosin[1].

  • CAS Number: 99764-63-3
  • MF: C36H56F3N7O12
  • MW: 835.86500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A