Dibenzo(a,i)pyrene-d14 is the deuterium labeled Dibenzo(a,i)pyrene[1].
PPARγ agonist 7 (Compound 3a) is a potent and selective agonist of PPARγ. PPARγ agonist 7 promotes adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs) as a novel PPARγ full agonist (EC50, 4.34 μM)[1].
MUC5AC-3/13 is a biological active peptide. (glycopeptide transferase, ppGaNTase-T9 substrate)
Momordin IIc (Quinoside D) is a triterpenoid glycoside isolated from Bougainvillea glabra[1].
Glycyltyrosine dihydrate is a tyrosine derivative[1].
Fenquinotrione is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor with IC50s of 27.2 and 44.7nM against rice and Arabidopsis thaliana HPPD, respectively. Fenquinotrione is an herbicide that can control a wide range of broadleaf and sedge weeds with excellent rice selectivity[1].
1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Boc-α-(4-fluorobenzyl)-DL-Pro-OH is a proline derivative[1].
Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a, the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research[1].
CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism[1].
Monosodium glutamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2, 4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.)
All-trans-retinal is a one of the major vitamin A metabolites in the retina. In physiological conditions, all-trans-RAL is regenerated to the visual chromophore, 11-cis-retinal.
N-tert-Butyloxycarbonyl-L-histidine is a histidine derivative[1].
(R)-2-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid is a phenylalanine derivative[1].
D-Erythrose-2-13C is the 13C labeled D-Erythrose[1].
Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free “Click Chemistry” reaction[1].
Stearyl Stearate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Fmoc-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative[1].
Dafadine-A, an analog of dafadine, is a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans; also inhibits the mammalian ortholog of DAF-9(CYP27A1). IC50 value:Target: DAF-9(CYP27A1) inhibitorThe DAF-9 cytochrome P450 is a key regulator of dauer formation, developmental timing and longevity in the nematodeCaenorhabditis elegans. Here we describe the first identified chemical inhibitor of DAF-9 and the first reported small-molecule tool that robustly induces dauer formation in typical culture conditions. This molecule (called dafadine) also inhibits the mammalian ortholog of DAF-9(CYP27A1), suggesting that dafadine can be used to interrogate developmental control and longevity in other animals.
Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety[1].
GHGVYGHGVYGHGPYGHGPYGHGLYW (DgHBP-2) is 26-amino-acid-long consensus peptide derived from histidine-rich beak protein-2 (DgHBP-2). GHGVYGHGVYGHGPYGHGPYGHGLYW can be used fabricated glucose-responsive insulin delivery system[1].
Fmoc-D-Thr(Trt)-OH is a threonine derivative[1].
Me-CO-Lys(Cbo)-Gly-Arg-pNA is a substrate for C1 esterase[1].
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
Fura Red is a Ca2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca2+][1].
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.
Pent-4-en-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cholesteryl 10-undecenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1].