Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Sibiricaxanthone B

Sibiricaxanthone B is a xanthone isolated from Polygala tenuifolia[1].

  • CAS Number: 241125-81-5
  • MF: C24H26O14
  • MW: 538.455
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 964.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 328.7±27.8 °C

semicochliodinol

Semicochliodinol can be isolated from rice cultures of the fungus genus Chaetomium[1].

  • CAS Number: 194224-72-1
  • MF: C27H22N2O4
  • MW: 438.47
  • Catalog: Others
  • Density: 1.456±0.06 g/cm3(Predicted)
  • Boiling Point: 766.8±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

7-Deaza-7-propargylamino-ddATP

7-Deaza-7-propargylamino-ddATP is an analog of dideoxyadenosine triphosphate (ddATP) that can be used for gene sequencing[1].

  • CAS Number: 114748-69-5
  • MF: C14H20N5O11P3
  • MW: 527.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pseudolaric acid C2-O-β-D-glucoside

Pseudolaric acid C2-O-β-D-glucoside is a natural product isolated from Pseudolarix kaempferi[1].

  • CAS Number: 1206462-80-7
  • MF: C28H36O13
  • MW: 580.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

agrimoniin

Agrimoniin is a phenolic compound isolated in the fruit of Fragaria vesca[1].

  • CAS Number: 82203-01-8
  • MF: C82H54O52
  • MW: 1871.27000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetate hydrochloride

Ethyl 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetate hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 347890-34-0
  • MF: C11H23ClN2O4
  • MW: 282.764
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 352ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 166.7ºC

Diafenthiuron

Diafenthiuron is a thiourea compound commonly used pesticide. Diafenthiuron inhibits mitochondrial functioning in insect pests[1].

  • CAS Number: 80060-09-9
  • MF: C23H32N2OS
  • MW: 384.578
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 448.8±55.0 °C at 760 mmHg
  • Melting Point: 144.6-147.7°C
  • Flash Point: 225.2±31.5 °C

ATTO 425 azide

ATTO 425 Azide is an azide derivative of ATTO 425, the maximum excitation and emission wavelength: 439/489 nm.

  • CAS Number: 1609584-73-7
  • MF: C30H43N5O8
  • MW: 601.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

C7280948

C-7280948 is a PRMT1 inhibitor.IC50 value:Target: PRMT1in vitro: Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1.

  • CAS Number: 587850-67-7
  • MF: C14H16N2O2S
  • MW: 276.354
  • Catalog: Histone Methyltransferase
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 481.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 244.8±31.5 °C

2-Amino-3-(4-hydroxyphenyl)propanehydrazide

L-Tyrosine Hydrazide is a tyrosine derivative[1].

  • CAS Number: 7662-51-3
  • MF: C9H13N3O2
  • MW: 195.218
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 490.8±40.0 °C at 760 mmHg
  • Melting Point: 196-198 °C(lit.)
  • Flash Point: 250.6±27.3 °C

Dipyrrometheneboron difluoride

Dipyrrometheneboron difluoride is a green-fluorescent dye used for labeling nonpolar lipids and detecting calcium.

  • CAS Number: 138026-71-8
  • MF: C9H7BF2N2
  • MW: 191.97
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PHI-27 (rat)

PHI-27 (rat) is a 27 amino acid peptide.PHI-27 (rat) is used to find peptide hormones and other active peptides[1].

  • CAS Number: 96849-38-6
  • MF: C136H216N36O41
  • MW: 3011.39000
  • Catalog: Others
  • Density: 0.98g/cm3
  • Boiling Point: 250.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 105.6ºC

(2R,4R)-Fmoc-D-Pro(4-N3)-OH

(2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group[1].

  • CAS Number: 1378847-51-8
  • MF: C20H18N4O4
  • MW: 378.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl 3-(4-methoxyphenyl)propanoate

Ethyl-p-methoxyhydrocinnamate is a phenolic compound that can be isolated from the edible rhizomes of Erythrina variegate[1].

  • CAS Number: 22767-72-2
  • MF: C12H16O3
  • MW: 208.25
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 291.1±15.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 117.7±15.0 °C

MFN2 agonist B-A l

MFN2 agonist B-A l is a mall-molecule mimics of the peptide-peptide interface of MFN2, allosterically activates MFN2 and promotes mitochondrial fusion with EC50 of 3 nM; potently stimulates mitochondrial fusion in MFN2-deficient cells, competed for minipeptide binding at the MFN2 HR2 interaction site, correct mitochondrial damage induced by nonfunctioning MFN2 mutants by activating endogenous mitofusins by amelioration of mitochondrial dysmotility, fragmentation, depolarization, and clumping; normalizes axonal mitochondrial trafficking within sciatic nerves of MFN2 Thr105→Met105 mice.

  • CAS Number: 2230047-87-5
  • MF: C21H29N5OS
  • MW: 399.557
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lithospermic acid

Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo[1].

  • CAS Number: 28831-65-4
  • MF: C27H22O12
  • MW: 538.456
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 862.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 291.3±27.8 °C

Gluconate-1-13C sodium

Gluconate-1-13C sodium is the 13C labeled Gluconate sodi[1][2].

  • CAS Number: 2687959-99-3
  • MF: C513CH11NaO7
  • MW: 219.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(2-Aminooxyethyl)-7-DCCAm

N-(2-Aminooxyethyl)-7-DCCAm (Compound 7) is a fluorescent dye, and can be used for protein labeling[1].

  • CAS Number: 1384475-20-0
  • MF: C16H21N3O4
  • MW: 319.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chlorophenol red-beta-d-galactopyranosid

Chlorophenol red-β-D-galactopyranoside is a long-wavelength dye, which has been widely used for colorimetric assays. Chlorophenol red-β-D-galactopyranoside is also a β-galactosidase substrate commonly used in recombinant yeast oestrogenic assays[1][2].

  • CAS Number: 99792-79-7
  • MF: C25H22Cl2O10S
  • MW: 585.407
  • Catalog: Others
  • Density: 1.661
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Dap(Alloc)-OH

Fmoc-Dap(Alloc)-OH is an alanine derivative[1].

  • CAS Number: 188970-92-5
  • MF: C22H22N2O6
  • MW: 410.420
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 658.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 352.1±31.5 °C

Cytosine-13C,15N2

Cytosine-13C,15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3].

  • CAS Number: 181517-10-2
  • MF: C4H5N3O
  • MW: 114.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TFLLRNPNDK-NH2

TFLLRNPNDK-NH2 is a biological active peptide. (This peptide is a thrombin receptor activating peptide. This PAR-1 agonist peptide reversibly binds to PAR-1 mimicking the 'tethered ligand' that thrombin makes available through proteolytic cleavage of substrate. It is also known to cause increase in liquid and protein permeability much like thrombin.)

  • CAS Number: 145229-90-9
  • MF: C54H89N17O15
  • MW: 1216.39
  • Catalog: Thrombin
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PSMA I&S

PSMA I&S is a precursor of the 99mTc-labeled PSMA-targeting ligand[1].

  • CAS Number: 2639475-07-1
  • MF: C59H82N10O21S
  • MW: 1299.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-D-Orn(Boc)-OH

N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC)[1].

  • CAS Number: 2165877-62-1
  • MF: C10H18N4O4
  • MW: 258.27
  • Catalog: ADC Linker
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Triacetin

Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

  • CAS Number: 102-76-1
  • MF: C9H14O6
  • MW: 218.204
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 258.0±0.0 °C at 760 mmHg
  • Melting Point: 3 °C(lit.)
  • Flash Point: 148.9±0.0 °C

L-Serine,N-(2,4-dinitrophenyl)

N-(2,4-Dinitrophenyl)-L-serine is a serine derivative[1].

  • CAS Number: 1655-64-7
  • MF: C9H9N3O7
  • MW: 271.18400
  • Catalog: Others
  • Density: 1.715g/cm3
  • Boiling Point: 585.3ºC at 760mmHg
  • Melting Point: 177 °C
  • Flash Point: 307.8ºC

ABP 688

ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].

  • CAS Number: 924298-51-1
  • MF: C15H16N2O
  • MW: 240.30000
  • Catalog: mGluR
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SBI-115

SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibitingTGR5[1].

  • CAS Number: 882366-16-7
  • MF: C14H13ClN2O4S
  • MW: 340.78
  • Catalog: GPCR19
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Cyclohexyl-3-aminopropanesulfonic acid

CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[1][2].

  • CAS Number: 1135-40-6
  • MF: C9.H19.N.O3.S
  • MW: 221.32
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: >300 °C(lit.)
  • Flash Point: N/A

6'-O-β-D-Apiofuranosylsweroside

6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall[1].

  • CAS Number: 266678-59-5
  • MF: C21H30O13
  • MW: 490.455
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 800.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 276.6±27.8 °C