Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

N,N,N-Trimethylmethanaminium hexafluorophosphate

Tetramethylammonium Hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 558-32-7
  • MF: C4H12F6NP
  • MW: 219.10900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300 °C(lit.)
  • Flash Point: N/A

Z-Gly-Phe-OH

Z-Gly-Phe is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1170-76-9
  • MF: C19H20N2O5
  • MW: 356.37300
  • Catalog: Others
  • Density: 1.278 g/cm3
  • Boiling Point: 646ºC at 760 mmHg
  • Melting Point: 125-126 °C
  • Flash Point: 344.5ºC

glyasperin a

Glyasperin A is a flavonoid compound isolated from the acetone extract of the leaves of Macaranga gigantea[1].

  • CAS Number: 142474-52-0
  • MF: C25H26O6
  • MW: 422.470
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 643.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.4±25.0 °C

UDP-rhamnose

UDP-rhamnose is one of the substrates for pectin synthesis in cell wall. UDP-rhamnose can be identified in fungi, it is one of the most common sugar donor in plants[1].

  • CAS Number: 1955-26-6
  • MF: C15H24N2O16P2
  • MW: 550.30200
  • Catalog: Others
  • Density: 1.9g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calceolarioside B

Calceolarioside B is a natural product isolated from Stauntonia hexaphylla leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM [1].

  • CAS Number: 105471-98-5
  • MF: C23H26O11
  • MW: 478.446
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 799.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.2±26.4 °C

Homocapsaicin II

Homocapsaicin II is a pungent compound, that can be isolated from fruits of Capsicum annuum L[1].

  • CAS Number: 71240-51-2
  • MF: C19H29NO3
  • MW: 319.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-O-Galloyl-2-O-cinnamoyl-glucose

1-O-Galloyl-2-O-cinnamoyl-glucose is a natural compound that could be found in R. palmatum L.[1].

  • CAS Number: 791836-69-6
  • MF: C22H22O11
  • MW: 462.4
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 800.8±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Acesulfame-d4 (potassium salt)

Acesulfame-d4 potassiumis the deuterium labeledAcesulfame (potassium)(HY-D0195)[1]. Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice[2].

  • CAS Number: 1623054-53-4
  • MF: C4D4KNO4S
  • MW: 205.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Levanase

Levanase is a slime-dissolving enzyme of Rhodotorula species. Levanase performs random hydrolysis of β-2,6 fructofuranosyl linkages in β-2,6 fructans containing more than 3 fructose units[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tri-p-tolylamine-d21

Tri-p-tolylamine-d21 is the deuterium labeled Tri-p-tolylamine[1].

  • CAS Number: 201944-90-3
  • MF: C21D21N
  • MW: 308.52800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cholera autoinducer 1

Cholera autoinducer 1 is Vibrio cholerae autoinducer (S)-3-hydroxytridecan-4-one. Cholera autoinducer 1 influences chemotaxis in C. elegans[1].

  • CAS Number: 1004296-82-5
  • MF: C13H26O2
  • MW: 214.34400
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 251.0±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 103.4±11.0 °C

BAPTA tetrapotassium salt

BAPTA tetrapotassium is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+. BAPTA tetrapotassium is a valuable tool to study the role of calcium in cell signaling[1][2].

  • CAS Number: 73630-08-7
  • MF: C22H20K4N2O10
  • MW: 628.795
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 766.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 417.4ºC

2,2'-[[6,6,12,12-tetrakis(4-hexylphenyl)-s-indacenodithieno[3,2-b]thiophene]methylidyne(3-oxo-1H-indene-2,1(3H)-diylidene)]]bis(propanedinitrile)

ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes.ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.

  • CAS Number: 1664293-06-4
  • MF: C94H82N4O2S4
  • MW: 1427.94000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ala-Ser-OH

Ala-Ser is a biologically active peptide.

  • CAS Number: 3303-41-1
  • MF: C6H12N2O4
  • MW: 176.17000
  • Catalog: Others
  • Density: 1.354g/cm3
  • Boiling Point: 486.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 248.2ºC

AMARA peptide TFA

AMARA peptide is a substrate for SIK and AMPK.

  • CAS Number: 163560-19-8
  • MF: C62H115N27O17S
  • MW: 1542.81
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-620473

WAY-620473 is an active molecule.

  • CAS Number: 743451-55-0
  • MF: C17H20N4O3
  • MW: 328.371
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyproconazole

Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.In vitro: Cyproconazole has been shown to cause a dose dependent inhibition of progesterone production in human placental cells in vitro. cyproconazole exhibited the lowest capacity to increase CYP1A1 and were not able to activate the AhR in the transactivation assay. [1]In vivo: Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. In wild-type mice, 200 ppm cyproconazole caused liver hypertrophy, increased liver weight and cell proliferation, single-cell necrosis and fat vacuolation. [2]

  • CAS Number: 94361-06-5
  • MF: C15H18ClN3O
  • MW: 291.77600
  • Catalog: Bacterial
  • Density: 1.32
  • Boiling Point: >250ºC
  • Melting Point: 106.2-106.9ºC
  • Flash Point: >100 °C

Ethyl trans-2-decenoate

Ethyl trans-2-Decenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 7367-88-6
  • MF: C12H22O2
  • MW: 198.30200
  • Catalog: Others
  • Density: 0.88 g/mL at 25 °C(lit.)
  • Boiling Point: 251 °C(lit.)
  • Melting Point: N/A
  • Flash Point: 195 °F

Isoanhydroicaritin

Isoanhydroicaritin is a flavonoid isolated from the dried root of S. flavescens[1].

  • CAS Number: 28610-30-2
  • MF: C21H20O6
  • MW: 368.380
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 610.4±55.0 °C at 760 mmHg
  • Melting Point: 275 ºC
  • Flash Point: 217.9±25.0 °C

Phenyl isopropylcarbamate-d7

Phenyl isopropylcarbamate-d7 isopropylcarbamate-d7 is the deuterium labeled Phenyl isopropylcarbamate[1].

  • CAS Number: 1329835-22-4
  • MF: C10H6D7NO2
  • MW: 186.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kushenol I

Kushenol I is a natural compound isolated from the roots of Sophora flavescens[1].

  • CAS Number: 99119-69-4
  • MF: C26H30O7
  • MW: 438.470
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 676.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 230.9±25.0 °C

Sanggenone N

Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC50 of 23.45 μM[1].

  • CAS Number: 92280-12-1
  • MF: C25H26O6
  • MW: 422.47
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 592.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.2±23.6 °C

5-Pyrrolidinomethyluridine

5-Pyrrolidinomethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 1613530-41-8
  • MF: C14H21N3O6
  • MW: 327.33
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ATX inhibitor 11

ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].

  • CAS Number: 2485779-27-7
  • MF: C32H35N5O6
  • MW: 585.65
  • Catalog: Phosphodiesterase (PDE)
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-octadecanoyl-nile blue

Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble[1].

  • CAS Number: 125829-24-5
  • MF: C38H53N3O2
  • MW: 583.84600
  • Catalog: Others
  • Density: 1.06 g/cm3
  • Boiling Point: 680.824ºC at 760 mmHg
  • Melting Point: 91-93ºC(lit.)
  • Flash Point: 365.549ºC

UNII:C19D0413EL

a-Hydroxymetoprolol is a metabolite of metoprolol. The adrenoreceptor blocking effect of a-Hydroxymetoprolol on metoprolol is almost zero[1].

  • CAS Number: 56392-16-6
  • MF: C15H25NO4
  • MW: 283.363
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 437.6±45.0 °C at 760 mmHg
  • Melting Point: 65-67ºC
  • Flash Point: 218.4±28.7 °C

exo-BCN-NHS carbonate

exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

  • CAS Number: 1493802-77-9
  • MF: C15H17NO5
  • MW: 291.30
  • Catalog: Others
  • Density: 1.35±0.1 g/cm3(Predicted)
  • Boiling Point: 412.8±28.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

H-Val-Arg-OH

H-Val-Arg-OH is a dipeptide consisting of valine and arginine, used in biochemical research[1].

  • CAS Number: 37682-75-0
  • MF: C11H23N5O3
  • MW: 273.33200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PRMT5-IN-10

PRMT5-IN-10 has promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex.

  • CAS Number: 2567564-23-0
  • MF: C13H17N5O4
  • MW: 307.31
  • Catalog: Histone Methyltransferase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyrromethene 650

Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.

  • CAS Number: 157410-23-6
  • MF: C16H18BF2N3
  • MW: 301.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 255 °C
  • Flash Point: N/A