Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Periplanetin

Periplanetin, a 1-benzoyl-β-d-glucose, can be isolated from the secretion of the laterocervical organ of Periplaneta americana L. and Blatta orientalis L[1].

  • CAS Number: 21056-52-0
  • MF: C13H16O7
  • MW: 284.26
  • Catalog: Others
  • Density: 1.5g/cm3
  • Boiling Point: 507.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.1ºC

(+)-N-Formylnorglaucine

(+)-N-Formylnorglaucine is an aporphine alkaloid isolated from the leaves of Unonopsis stipitata. (+)-N-Formylnorglaucine contains a formyl group linked to the heterocyclic nitrogen[1].

  • CAS Number: 371196-16-6
  • MF: C21H23NO5
  • MW: 369.417
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3β-Hydroxy-5-cholestenoic acid-d5

3β-Hydroxy-5-cholestenoic acid-d5 is deuterium labeled 3β-Hydroxy-5-cholestenoic acid.

  • CAS Number: 1620239-03-3
  • MF: C27H39D5O3
  • MW: 421.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

mSIRK

mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange[1].

  • CAS Number: 593267-11-9
  • MF: C93H150N20O25
  • MW: 1948.31
  • Catalog: ERK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LEVOBETAXOLOL

Levobetaxolol is a potent and high affinity β-adrenergic antagonist with IC50 values of 33.2, 2970, 709 nM for guinea pig atrial β1, tracheal β2 and rat colonic β3 receptors, respectively. Levobetaxolol reduces IOP (intraocular pressure). Levobetaxolol exhibits a micromolar affinity for L-type Ca21-channels. Levobetaxolol decreases the effects of ischaemia/reperfusion injury in rats. Levobetaxolol has the potential for the research of glaucoma[1][2].

  • CAS Number: 93221-48-8
  • MF: C18H29NO3
  • MW: 307.42800
  • Catalog: Adrenergic Receptor
  • Density: 1.067g/cm3
  • Boiling Point: 448ºC at 760 mmHg
  • Melting Point: 71-72ºC
  • Flash Point: 224.7ºC

UNII:DPY9K1927C

3,7-Dimethyloctan-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 106-21-8
  • MF: C10H22O
  • MW: 158.281
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 212.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 95.0±0.0 °C

L-Lysine-d9 dihydrochloride

L-Lysine-d9 (dihydrochloride) is the deuterium labeled Boc-L-Ala-OH[1].

  • CAS Number: 2483831-52-1
  • MF: C6H7D9Cl2N2O2
  • MW: 228.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TRP-601

TRP-601 is a caspase inhibitor.

  • CAS Number: 1094569-02-4
  • MF: C40H48F2N6O11
  • MW: 826.852
  • Catalog: Bcl-2 Family
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

neoschaftoside

Neoschaftoside is a natural product that can be isolated from Viola yedoensis[1].

  • CAS Number: 61328-41-4
  • MF: C26H28O14
  • MW: 564.49200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SPHINX31

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), which is a SRPK1 substrate. SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].

  • CAS Number: 1818389-84-2
  • MF: C27H24F3N5O2
  • MW: 507.51
  • Catalog: SRPK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2',2'-Dimethyl-2H,2'H-3,8'-bichromene-5',7-diol

Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM[1][2].

  • CAS Number: 60008-03-9
  • MF: C20H18O4
  • MW: 322.354
  • Catalog: Tyrosinase
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 536.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.2±30.1 °C

2,4-Hexadienoic acid,methyl ester

Methyl hexa-2,4-dienoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 1515-80-6
  • MF: C7H10O2
  • MW: 126.15300
  • Catalog: Others
  • Density: 0.935g/cm3
  • Boiling Point: 180ºC(lit.)
  • Melting Point: 8ºC
  • Flash Point: 63.1ºC

Ethoxylated hydrogenated castor oil

Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1].

  • CAS Number: 61788-85-0
  • MF: C21H23ClFNO2
  • MW: 375.864
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 529.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 273.8±30.1 °C

(2S,4R)-Fmoc-L-Pro(4-N3)-OH

(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide[1].

  • CAS Number: 702679-55-8
  • MF: C20H18N4O4
  • MW: 378.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-β-homoserine

(S)-3-Amino-4-hydroxybutanoic acid is a serine derivative[1].

  • CAS Number: 16504-57-7
  • MF: C4H9NO3
  • MW: 119.119
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 374.5±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 180.3±25.1 °C

H-Lys-Ala-OH hydrobromide salt

H-Lys-Ala-OH is adipeptide.

  • CAS Number: 17043-71-9
  • MF: C9H19N3O3
  • MW: 217.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ser-Phe-OH

H-Ser-Phe-OH is a biologically active peptide.

  • CAS Number: 16875-28-8
  • MF: C12H16N2O4
  • MW: 252.26600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GLPG2938

GLPG2938 is a potent and selective S1P2 antagonist. GLPG2938 can be used for the research of idiopathic pulmonary fibrosis[1].

  • CAS Number: 2130996-00-6
  • MF: C20H19F6N7O2
  • MW: 503.4
  • Catalog: LPL Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secoxyloganin methyl ester

Dimethyl secologanoside (compound 2) is an e iridoid isolated from the leaves of Khaya senegalensis[1].

  • CAS Number: 74713-15-8
  • MF: C18H26O11
  • MW: 418.39
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 586.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 204.1±23.6 °C

Pinacidil hydrate

Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator.

  • CAS Number: 85371-64-8
  • MF: C13H21N5O
  • MW: 263.34
  • Catalog: Potassium Channel
  • Density: N/A
  • Boiling Point: 356.7ºC at 760 mmHg
  • Melting Point: 164-165ºC
  • Flash Point: 169.5ºC

N-BENZYLGLYCINE TERT-BUTYL ESTER

tert-Butyl benzylglycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 7662-76-2
  • MF: C13H19NO2
  • MW: 221.29500
  • Catalog: Others
  • Density: 1.019±0.06 g/cm3(Predicted)
  • Boiling Point: 151-152 °C(Press: 12 Torr)
  • Melting Point: N/A
  • Flash Point: N/A

Tween 80

Tween 80 is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation.

  • CAS Number: 9005-65-6
  • MF: C46H52N5O8P
  • MW: 833.907
  • Catalog: Biochemical Assay Reagents
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 695.8±55.0 °C at 760 mmHg
  • Melting Point: -21ºC
  • Flash Point: 207.1±25.0 °C

Acetylcholine Bromide

Acetylcholine (bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 66-23-9
  • MF: C7H16BrNO2
  • MW: 226.111
  • Catalog: CDK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 140-143 °C(lit.)
  • Flash Point: N/A

Potassium hydrogen phosphate hydrate (2:1:3)

Dipotassium hydrogen phosphate trihydrate affects pH level in liquid. Dipotassium hydrogen phosphate (trihydrate) can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 16788-57-1
  • MF: H7K2O7P
  • MW: 228.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium

1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 (sodium) is deuterium labeled 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

  • CAS Number: 2342575-18-0
  • MF: C25H45D5NNaO9P
  • MW: 567.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Brilliant Blue FCF

Brilliant Blue FCF has the appearance of a reddish-blue powder. It is soluble in water, and the solution has a maximum absorption at about 628 nanometers. It is a synthetic dye produced using aromatic hydrocarbons from petroleum, is a colorant for foods and other substances.

  • CAS Number: 3844-45-9
  • MF: C37H34N2Na2O9S3
  • MW: 792.848
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 283 °C (dec.)(lit.)
  • Flash Point: N/A

1,3,6,8-PYRENETETRASULFONIC ACID TETRASODIUM SALT

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO2 release[1][2][3].

  • CAS Number: 59572-10-0
  • MF: C16H6Na4O12S4
  • MW: 610.43100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 102-104 °C(lit.)
  • Flash Point: N/A

Melittoside

Melittoside is a natural compound.

  • CAS Number: 19467-03-9
  • MF: C21H32O15
  • MW: 524.470
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 890.0±65.0 °C at 760 mmHg
  • Melting Point: 167-168 ºC
  • Flash Point: 492.1±34.3 °C

Cyclo(Ile-Ala)

Cyclo(Ile-Ala) is found in marine actinomycete 11014 I.[1].

  • CAS Number: 90821-99-1
  • MF: C9H16N2O2
  • MW: 184.24
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 432.0±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.2±26.9 °C

D-Sorbitol-d4

D-Sorbitol-d4 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet

  • CAS Number: 2714472-87-2
  • MF: C6H10D4O6
  • MW: 186.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A