Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Endo-1,5-α-arabinanase

Endo-1,5-α-arabinanase (Endo-1,5-arabinanase) belongs to CAZy family 43 of the glycoside hydrolase (GH). Endo-1,5-α-arabinanase mainly shorts arabinooligosaccharides and arabinose from debranched arabinan[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R,4S)-1-BOC-4-AMINO-PYRROLIDINE-2-CARBOXYLIC ACID

(4S)-1-Boc-4-amino-D-proline is an amino acid derivative that can be used for compound synthesis[1].

  • CAS Number: 132622-78-7
  • MF: C10H18N2O4
  • MW: 230.26100
  • Catalog: Others
  • Density: 1.233g/cm3
  • Boiling Point: 371.073ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 178.219ºC

Erythrabyssin II

Erythrabyssin II is a natural product that can be isolated from the stem bark of Erythrina crista-galli[1].

  • CAS Number: 77263-06-0
  • MF: C25H28O4
  • MW: 392.49
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 541.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 281.4±30.1 °C

(2α,3β)-Olean-12-ene-2,3-diol

(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton[1].

  • CAS Number: 26926-98-7
  • MF: C30H50O2
  • MW: 442.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methiocarb sulfone-d3

Methiocarb sulfone-d3 is the deuterium labeled Methiocarb sulfone[1].

  • CAS Number: 2733969-33-8
  • MF: C11H12D3NO4S
  • MW: 260.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mifamurtide sodium hydrate

Mifamurtide (sodium hydrate) (MTP-PE (sodium hydrate); L-MTP-PE (sodium hydrate); CGP 19835 (sodium hydrate)) is the sodium hydrate of mifamurtide. Mifamurtide is a nonspecific immunomodulator that acts by stimulating immune responses by activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and is used as an insulin sensitizer and may also be used in osteosarcoma research[1][2][3].

  • CAS Number: 838853-48-8
  • MF: C59H110N6NaO20P
  • MW: 1277.496
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ent-16β,17-Dihydroxykauran-19-oic acid

ent-16β,17-Dihydroxykauran-19-oic acid is an anti-inflammatory agent, which can be isolated from Siegesbeckia pubescens herb. ent-16β,17-Dihydroxykauran-19-oic acid inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia[1].

  • CAS Number: 3301-61-9
  • MF: C20H32O4
  • MW: 336.47
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 505.6±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 273.6±22.4 °C

3-Methylsalicylic acid

3-Methylsalicylic acid is a salicylic acid derivative compound with marked fibrinolytic activity in human plasma by activating its fibrinolytic system.

  • CAS Number: 83-40-9
  • MF: C8H8O3
  • MW: 152.147
  • Catalog: Cardiovascular Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 293.2±28.0 °C at 760 mmHg
  • Melting Point: 98-100 °C(lit.)
  • Flash Point: 145.4±20.5 °C

4-[6-[16-[2-(2,4-dicarboxyphenyl)-5-methoxy-1-benzofuran-6-yl]-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]-5-methoxy-1-benzofuran-2-yl]benzene-1,3-dicarboxylic acid

PBFI is the fluorescent indicator that is widely used for the determination of intracellular concentrations of K+[1].

  • CAS Number: 124549-11-7
  • MF: C46H46N2O16
  • MW: 882.86100
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nicotinyl alcohol

3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent[1][2].

  • CAS Number: 100-55-0
  • MF: C6H7NO
  • MW: 109.126
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 266.0±0.0 °C at 760 mmHg
  • Melting Point: -7 °C
  • Flash Point: 97.5±20.4 °C

savinin

Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].

  • CAS Number: 493-95-8
  • MF: C20H16O6
  • MW: 352.34
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 573.5±39.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 254.5±27.1 °C

Mast Cell Degranulating (MCD) Peptide HR-2

Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release[1].

  • CAS Number: 80388-04-1
  • MF: C77H135N17O14
  • MW: 1523.00
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-His(Trt)-OH

Boc-His(Trt)-OH is a histidine derivative[1].

  • CAS Number: 32926-43-5
  • MF: C30H31N3O4
  • MW: 497.585
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 667.5±55.0 °C at 760 mmHg
  • Melting Point: ~130 °C (dec.)
  • Flash Point: 357.5±31.5 °C

10,11-Dihydro-24-hydroxyaflavinine

10,11-Dihydro-24-hydroxyaflavinine (10,23,24,25-tetrahydro-24-hydroxyaflavinine), an aflavinine analog, is a natural product that can be isolated from Ascostromata of Eupenicillium crustaceum[1].

  • CAS Number: 171569-81-6
  • MF: C28H41NO2
  • MW: 423.63
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 589.6±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 310.4±24.6 °C

Polyphyllin E

Polyphyllin E is a steroidal saponin that can be isolated from Paris polyphylla[1].

  • CAS Number: 76296-73-6
  • MF: C51H82O20
  • MW: 1015.185
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(±)-2-Methylbutyryl chloride-d9

(±)-2-Methylbutyryl chloride-d9 is the deuterium labeled (±)-2-Methylbutyryl chloride[1].

  • CAS Number: 1219795-10-4
  • MF: C5ClD9O
  • MW: 129.63
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

UDP-GalNAz.2Na

UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor[1].

  • CAS Number: 653600-61-4
  • MF: C17H24N6O17P2Na2
  • MW: 692.05
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methyl-2-cyclohexen-1-ol

3-Methylcyclohex-2-en-1-ol, isolated fromDendroctonus, is a potent antiaggregative pheromone[1].

  • CAS Number: 21378-21-2
  • MF: C7H12O
  • MW: 112.17000
  • Catalog: Others
  • Density: 0.977g/cm3
  • Boiling Point: 199ºC at 760mmHg
  • Melting Point: 56 °C/1 mmHg (lit.)
  • Flash Point: 71.7ºC

Semicarbazide hydrochloride

Semicarbazide hydrochloride, a derivative of urea, possesses antiviral, antiinfective and antineoplastic through binding to copper or iron in cells[1].

  • CAS Number: 563-41-7
  • MF: CH6ClN3O
  • MW: 111.531
  • Catalog: Infection
  • Density: 1.286g/cm3
  • Boiling Point: 235.3ºC at 760 mmHg
  • Melting Point: 175-177 °C (dec.)(lit.)
  • Flash Point: 66.5ºC

H-Gly-His-Arg-Pro-NH2 acetate salt

H-Gly-His-Arg-Pro-NH is a biologically active polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of drug research and development[1].

  • CAS Number: 209623-54-1
  • MF: C19H32N10O4
  • MW: 464.522
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ACTH (4-9)

ACTH (4-9) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (4-9) is the 4-9 sequence fragment of ACTH[1][2].

  • CAS Number: 56236-83-0
  • MF: C42H56N12O9S
  • MW: 905.03400
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PTGR2-IN-1

PTGR2-IN-1 is a potent PTGR2 inhibitor with an IC50 of ~0.7 μM. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells[1].

  • CAS Number: 349093-44-3
  • MF: C19H22N2O2
  • MW: 310.390
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 512.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.0±30.1 °C

Tau Peptide (255-314) (Repeat 2 Domain) (human) trifluoroacetate salt

Tau Peptide (255-314) (Repeat 2 Domain) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 2022995-68-0
  • MF: C277H467N83O86S
  • MW: 6368.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clopidogrel-d3 hydrochloride

Clopidogrel-d3 (hydrochloride) is the deuterium labeled Clopidogrel hydrochloride[1].

  • CAS Number: 2140305-74-2
  • MF: C16H14D3Cl2NO2S
  • MW: 361.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LSTc

LSTc (LS-tetrasaccharide c) is a human lactooligosaccharide presents on glycoproteins and glycolipids. LSTc is also a specific human JC polyomavirus (JCV) recognition motif. LSTc has good potential for the study of progressive multifocal leukoencephalopathy (PML)[1].

  • CAS Number: 64003-55-0
  • MF: C37H62N2O29
  • MW: 998.88400
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Butylaniline-d9

4-Butylaniline-d9 is the deuterium labeled 4-Butylaniline[1].

  • CAS Number: 1219794-78-1
  • MF: C10H15N
  • MW: 149.233
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 261.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 101.7±0.0 °C

Apigenin-7-O-sophrosideApigenin-7-O-β-D-sophoroside

Apigenin 7-O-sophoroside is a flavonoid glycoside isolated from Lonicera gracilipes var. glandulosa[1].

  • CAS Number: 52073-83-3
  • MF: C27H30O15
  • MW: 594.52
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 965.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 320.7±27.8 °C

(2,2,3,3-2H4)Cyclopropanamine

Cyclopropyl-2,2,3,3-amine-d4 is the deuterium labeled Cyclopropanamine[1].

  • CAS Number: 1051418-97-3
  • MF: C3H3D4N
  • MW: 61.119
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 49.3±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: -25.6±0.0 °C

Virstatin

Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT[1][2].

  • CAS Number: 88909-96-0
  • MF: C16H13NO4
  • MW: 283.28
  • Catalog: Infection
  • Density: 1.403g/cm3
  • Boiling Point: 536.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.3ºC

Sec61-IN-2

Sec61-IN-2 (A347) is a protein secretion inhibitor (extracted from patent WO2020176863)[1].

  • CAS Number: 2484865-72-5
  • MF: C22H19N5OS
  • MW: 401.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A