Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

GALA

GALA is a biological active peptide. (GALA, a pH-sensitive fusogenic peptide, is a promising method to accelerate this step in order to enhance the expression of the desired proteins.)

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Perlolyrin

Perlolyrin (Tribulusterine) is an alkaloid that can be isolated from dried fruits of Tribulus terrestris[1].

  • CAS Number: 29700-20-7
  • MF: C16H12N2O2
  • MW: 264.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Praeroside II

Praeroside II is an angular-type pyranocoumarm glycoside. Praeroside II can be isolated from the n-butanol-extracts of P. praeruptorum Dunn. Praeroside II can be used for pharmacological study[1].

  • CAS Number: 86940-46-7
  • MF: C20H24O10
  • MW: 424.399
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 670.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.4±25.0 °C

Hexidium iodide

Hexidium iodide, a fluorescent nucleic binding acid stain (excitation/emission ~ 518/600 nm), permeants to mammalian cells and selectively stains almost all gram-positive bacteria. Hexidium iodide can bind to the DNA of all bacteria after permeabilization by EDTA[1][2].

  • CAS Number: 211566-66-4
  • MF: C25H28IN3
  • MW: 497.41400
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Epetraborole hydrochloride

Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of infections caused by Gram-negative bacteria. Epetraborole hydrochloride is a bacteriostatic compound that can against a wide range of anaerobic and Gram-negative bacteria, including multidrug-resistant pathogens, such as extended-spectrum-β-lactamase-, metallo-β-lactamase-, and carbapenemase-producing organism.

  • CAS Number: 1234563-16-6
  • MF: C11H17BClNO4
  • MW: 273.521
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

torachrysone

Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L[1].

  • CAS Number: 22649-04-3
  • MF: C14H14O4
  • MW: 246.259
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 457.1±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 176.3±20.8 °C

Androstenediol 17-acetate

Androstenediol 17-acetate is a synthetic anabolic-androgenic steroid and an androgen ester.

  • CAS Number: 5937-72-4
  • MF: C21H32O3
  • MW: 332.47700
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Ile-Glu-Pro-Phe-Ome

CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a human chymase inhibitor.

  • CAS Number: 252557-97-4
  • MF: C34H44N4O9
  • MW: 652.735
  • Catalog: Peptides
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 928.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 515.3±34.3 °C

Glycerol derivative 1

Glycerol derivative 1 is a Glycerol derivative extracted from patent EP 672415 A1, compound (1).

  • CAS Number: 128400-55-5
  • MF: C46H73ClN4O9
  • MW: 861.55
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

coniferyl aldehyde

Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

  • CAS Number: 458-36-6
  • MF: C10H10O3
  • MW: 178.185
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 338.8±27.0 °C at 760 mmHg
  • Melting Point: 80-82ºC(lit.)
  • Flash Point: 136.8±17.2 °C

5-Deoxystrigol

5-Deoxystrigol is a potent striga germination stimulant[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Simetryn

Simetryn is a herbicide with the LC50 of 16.9-3.70 mg/L (79.3-17.4 microM.

  • CAS Number: 1014-70-6
  • MF: C8H15N5S
  • MW: 213.303
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 302.5±25.0 °C at 760 mmHg
  • Melting Point: 82-83°C
  • Flash Point: 136.8±23.2 °C

4-(Trifluoromethyl)benzoic acid-13C6

4-(Trifluoromethyl)benzoic acid-13C6 is the 13C labeled 4-(Trifluoromethyl)benzoic acid[1].

  • CAS Number: 2731552-41-1
  • MF: C213C6H5F3O2
  • MW: 196.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2,3-Propanetriyl tri(2H29)pentadecanoate

pentadecanoate-d29 is the deuterium labeled pentadecanoate.

  • CAS Number: 352431-43-7
  • MF: C48H5D87O6
  • MW: 852.78
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 732.1±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.7±23.8 °C

GT-1

GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.

  • CAS Number: 1401527-90-9
  • MF: C29H30ClN11O11S2
  • MW: 808.20
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clemaphenol A

Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora[1].

  • CAS Number: 362606-60-8
  • MF: C20H22O6
  • MW: 358.385
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 560.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 292.5±30.1 °C

Acetylleucine

Acetylleucine is a drug used in the treatment of vertigo.

  • CAS Number: 99-15-0
  • MF: C8H15NO3
  • MW: 173.210
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 369.6±25.0 °C at 760 mmHg
  • Melting Point: 160ºC
  • Flash Point: 177.4±23.2 °C

H-Gly-Ala-Tyr-OH

Ala-Gly-Tyr is a tripeptide composed of L-alanine, glycine, and L-tyrosine joined in sequence by peptide linkages. Ala-Gly-Tyr has a role as a metabolite. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine.

  • CAS Number: 92327-84-9
  • MF: C14H19N3O5
  • MW: 309.31800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 705.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 380.1±32.9 °C

Auriculin A

Auriculin A is a synthetic atrial natriuretic factor (ANF) with hemodynamic effect. Auriculin A antagonizes renal vasoconstriction in the dog, and influences on arterial baroreflex control of heart rate, systemic blood pressure, and perfusion pressure in the hind limb (perfused at constant flow) in rabbits[1][2].

  • CAS Number: 91421-87-3
  • MF: C104H168N38O33S2
  • MW: 2542.81000
  • Catalog: Cardiovascular Disease
  • Density: 1.56
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-acetyl-s-benzyl-dl-cysteine

N-Acetyl-S-benzyl-DL-cysteine is a cysteine derivative[1].

  • CAS Number: 19538-71-7
  • MF: C12H15NO3S
  • MW: 253.31700
  • Catalog: Others
  • Density: 1.246g/cm3
  • Boiling Point: 506.2ºC at 760mmHg
  • Melting Point: 156ºC
  • Flash Point: 259.9ºC

fluclorolone acetonide

Flucloronide (Fluclorolone acetonide) is a corticosteroid for topical, and has anti-inflammatory activity[1].

  • CAS Number: 3693-39-8
  • MF: C24H29Cl2FO5
  • MW: 487.38800
  • Catalog: Inflammation/Immunology
  • Density: 1.38g/cm3
  • Boiling Point: 598.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 315.6ºC

BCECF-AM

BCECF-AM is a cell membrane permeable compound, widely used as a fluorescent indicator for intracellular pH.

  • CAS Number: 117464-70-7
  • MF: C40H36O19
  • MW: 820.70
  • Catalog: Dye Reagents
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 939.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 368.9±34.3 °C

1,4,5,6-Tetrahydroxy-7-prenylxanthone

1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone is a nature product that could be isolated from the stem barks of Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone has antiproliferative active. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone can be used in research of cancer[1].

  • CAS Number: 1001424-68-5
  • MF: C18H16O6
  • MW: 328.32
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 561.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.4±23.6 °C

Cyperenone

Cyperotundone is a sesquiterpene isolated from Nagarmotha (Cyperus rotundus)[1][2].

  • CAS Number: 3466-15-7
  • MF: C15H22O
  • MW: 218.33500
  • Catalog: Others
  • Density: 1.03±0.1 g/cm3
  • Boiling Point: 318.7±9.0℃ at 760 mmHg
  • Melting Point: 48 ºC
  • Flash Point: N/A

abecomotide

Abecomotide is a biological active peptide. (an immunological agent for active immunization)

  • CAS Number: 907596-50-3
  • MF: C45H79N13O16
  • MW: 1058.19
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1579.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 909.1±34.3 °C

AP-C3

AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1].

  • CAS Number: 682795-78-4
  • MF: C22H23N3O4
  • MW: 393.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-[3,4-Bis(benzyloxy)phenyl](2H3)ethanone

3′,4′-Dibenzyloxyaceto-phenone-d3 is the deuterium labeled 3′,4′-Dibenzyloxyaceto-phenone[1].

  • CAS Number: 344299-53-2
  • MF: C22H17D3O3
  • MW: 335.411
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 495.0±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 245.4±12.4 °C

1-Isomangostin

1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity[1].

  • CAS Number: 19275-44-6
  • MF: C24H26O6
  • MW: 410.46
  • Catalog: Metabolic Disease
  • Density: 1.257g/cm3
  • Boiling Point: 613.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 211.5ºC

bianfugenine

Dauriporphine, an alkaloid, can be isolated from the vines of Menispermum dauricum DC[1].

  • CAS Number: 88142-60-3
  • MF: C20H17NO5
  • MW: 351.35300
  • Catalog: Others
  • Density: 1.31g/cm3
  • Boiling Point: 602.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 318.3ºC

Cyclo(-D-Leu-D-Pro)

Cyclo(D-Leu-D-Pro) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 274680-11-4
  • MF: C11H18N2O2
  • MW: 210.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A