Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Boc-L-cyclopropylglycine

(S)-Butoxycarbonylamino-cyclopropyl-acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 155976-13-9
  • MF: C10H17NO4
  • MW: 215.246
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 364.7±25.0 °C at 760 mmHg
  • Melting Point: 112 °C
  • Flash Point: 174.4±23.2 °C

Norbornene-methyl-NHS

Norbornene-methyl-NHS is a click chemistry reagent containing a TCO group. Dienophile for conjugation via Diels-Alder-reaction, i.e. copper-free click reaction with tetrazines[1].

  • CAS Number: 1986791-87-0
  • MF: C13H15NO5
  • MW: 265.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

  • CAS Number: 326495-39-0
  • MF: C44H9D79NO8P
  • MW: 869.63
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,5-Dihydroxy-4-methoxyacetophenone

2,5-Dihydroxy-4-methoxyacetophenone (compounds 3) can be isolated from the 80% methanol extract of roots of Cynanchum paniculatum Kitagawa. 2,5-Dihydroxy-4-methoxyacetophenone inhibits glutamate-induced cytotoxicity in hippocampal HT22 cell line[1].

  • CAS Number: 22089-12-9
  • MF: C9H10O4
  • MW: 182.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secoxyloganin

Secoxyloganin, isolated from Lonicera japonica Thunb, inhibits the blood flow (BF) decrease. Secoxyloganin has allergy-preventive activity[1].

  • CAS Number: 58822-47-2
  • MF: C17H24O11
  • MW: 404.366
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 649.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 231.8±25.0 °C

Menbutone

Menbutone is an oxobutyric acid derivative, and is a choleretic.Menbutone has a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.

  • CAS Number: 3562-99-0
  • MF: C15H14O4
  • MW: 258.26900
  • Catalog: Inflammation/Immunology
  • Density: 1.249 g/cm3
  • Boiling Point: 511.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.6ºC

Cararosinol A

Cararosinol A is a compound isolated from the roots of Caragana sinica[1].

  • CAS Number: 651733-57-2
  • MF: C56H42O13
  • MW: 922.92
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Darutoside

Darutoside is a diterpenoid isolated from Siegesbeckia[1].

  • CAS Number: 59219-65-7
  • MF: C26H44O8
  • MW: 484.623
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 667.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 357.2±31.5 °C

Lurasidone Inactive Metabolite 14283

Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone. Lurasidone is a FDA approved drug for the treatment of schizophrenia.

  • CAS Number: 186204-32-0
  • MF: C28H37ClN4O3S
  • MW: 545.13600
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FSBA

FSBA? hydrochloride is a useful reagent for the affinity labeling of adenine nucleotide binding proteins and is mainly applied in the study of purified The labeling and subsequent detection of? these proteins can be blocked by including an excess of MgATP, which competes with FSBA for nucleotidebinding sites[1].

  • CAS Number: 78859-42-4
  • MF: C17H17ClFN5O7S
  • MW: 489.863
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Xipamide

Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1].

  • CAS Number: 14293-44-8
  • MF: C15H15ClN2O4S
  • MW: 354.809
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 255-256ºC
  • Flash Point: N/A

Boc-D-Glutamine

5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid is a glutamine derivative[1].

  • CAS Number: 61348-28-5
  • MF: C10H18N2O5
  • MW: 246.260
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 509.1±45.0 °C at 760 mmHg
  • Melting Point: 117-119ºC
  • Flash Point: 261.7±28.7 °C

CYCLO(-ASP-ASP)

Cyclo(Asp-Asp) is aCyclic dipeptide.

  • CAS Number: 35309-53-6
  • MF: C8H10N2O6
  • MW: 230.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine

N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

  • CAS Number: 2243974-78-7
  • MF: C35H38N6O6
  • MW: 638.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Podophyllotoxin β-D-glucoside

Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects[1].

  • CAS Number: 16481-54-2
  • MF: C28H32O13
  • MW: 576.546
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 781.3±60.0 °C at 760 mmHg
  • Melting Point: 152-154℃
  • Flash Point: 258.2±26.4 °C

[18F]-Labeled L-dopa precursor

[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa extracted from patent WO2014095739A1, example 8[1].

  • CAS Number: 1614253-58-5
  • MF: C35H36N2O7
  • MW: 596.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dihydrocurcumenone

Dihydrocurcumenone is a carabrane-type sesquiterpene. Dihydrocurcumenone can be isolated from Curcuma zedoaria, and the common form is 4-dihydrocurcumenone. Curcuma zedoaria sesquiterpene has vascular relaxation activity. 4-dihydrocurcumenone can inhibit the high concentration of K+ induced constriction of isolated rat aortic strips[1].

  • CAS Number: 142717-57-5
  • MF: C15H24O2
  • MW: 236.35000
  • Catalog: Cardiovascular Disease
  • Density: 1.042g/cm3
  • Boiling Point: 349.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 148.9ºC

Baloramotide

Baloramotide is a recombinant NY-ESO-1 protein containing 182 amino acids. Baloramotide increases the immune response against tumors[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Aspartic acid,N-benzoyl

N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins[1].

  • CAS Number: 4631-12-3
  • MF: C11H11NO5
  • MW: 237.20900
  • Catalog: Others
  • Density: 1.404g/cm3
  • Boiling Point: 502ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 257.4ºC

Azapropazone

Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID). Azapropazone can be used for the research of rheumatoid arthritis and other rheumatoid conditions[1].

  • CAS Number: 13539-59-8
  • MF: C16H20N4O2
  • MW: 300.36
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 438.0±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.7±26.8 °C

1,10-Phenanthroline

o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].

  • CAS Number: 66-71-7
  • MF: C12H8N2
  • MW: 180.205
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 365.1±15.0 °C at 760 mmHg
  • Melting Point: 114-117 °C(lit.)
  • Flash Point: 164.8±11.7 °C

MM-589

MM-589 is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) interaction. MM-589 binds to WDR5 with an IC50 of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12.7 nM[1].

  • CAS Number: 2097887-20-0
  • MF: C28H44N8O5
  • MW: 572.70
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tavolixizumab

Tavolixizumab (MEDI 0562; Tavolimab) is a human monoclonal antibody to TNFRSF4 (TNF receptor superfamily member 4) for use in cancer immunology research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(D-Trp6)-LHRH (1-6) amide

(D-Trp6)-LHRH (1-6) amide is a biologically active peptide.

  • CAS Number: 1217367-73-1
  • MF: C45H49N11O9
  • MW: 887.939
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1570.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 903.3±34.3 °C

7-Amino-4-methylcoumarin-3-acetic acid

7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm)[1].

  • CAS Number: 106562-32-7
  • MF: C12H11NO4
  • MW: 233.22000
  • Catalog: Others
  • Density: 1.391g/cm3
  • Boiling Point: 512.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 263.6ºC

Gardneramine

Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines[1].

  • CAS Number: 34274-91-4
  • MF: C23H28N2O5
  • MW: 412.479
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 570.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 298.7±32.9 °C

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate) is an antagonist for Substance P (HY-P0201) and Bombesin (HY-P0195) that has effects on ocular inflammatory responses to antidromic trigeminal nerve stimulation[1].

  • CAS Number: 143077-65-0
  • MF: C77H112N20O15
  • MW: 1557.84000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

17:0-16:1 PC-d5

17:0-16:1 PC-d5 is deuterium labeled 17:0-16:1 PC.

  • CAS Number: 2342575-79-3
  • MF: C41H75D5NO8P
  • MW: 751.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MAT2A inhibitor

MAT2A inhibitor is a methionine adenosyltransferase 2A (MATA2 ) inhibitor extracted from patent US20180079753, compound example 196 (4).

  • CAS Number: 2201057-10-3
  • MF: C31H22N6OS
  • MW: 526.61
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-[(Benzyloxy)carbonyl]-2-methylalanine

Z-Aib-OH is an alanine derivative[1].

  • CAS Number: 15030-72-5
  • MF: C4H9NO2
  • MW: 103.120
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 204.4±23.0 °C at 760 mmHg
  • Melting Point: 65-69ºC(lit.)
  • Flash Point: 77.4±22.6 °C