Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.
Nα-p-Tosyl-L-lysine methyl ester hydrochloride is a lysine derivative[1].
Morusignin L is an active compound that shows anti-osteoporosis activities[1][2].
Jatrophane 2 is a kind of jatrophane diterpene polyester obtained from the highly irritant extract of whole fresh plants of E. peplus L. (Euphorbiaceae)[1].
Blu667 is a highly potent and selective RET inhibitor with an IC50 of 0.4 nM for wild type RET kinase.
Simufilam (PTI-125) dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restores receptor and synaptic activities, reduces its a7nAChR/TLR4 associations and downstream pathologies. Simufilam dihydrochloride can be used for the research of Alzheimer's disease[1].
Bifikafusp alfa (L19-IL2) is an immunotherapy fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity[1].
Tyr-ACTH (4-9) is a behaviorally active peptide. Tyr-ACTH (4-9) can be used for research of learned behavior extinction in the rat[1].
Methyl α-D-glucopyranoside-13C is the 13C labeled Methyl α-D-glucopyranoside[1].
Big Endothelin-2 (1-38), human is a polypeptide.
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents[1][2].
Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.
Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone is a neuroprotective agent[1]. Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cell[1].
Biotin-Gastrin-1, human (1-17) is a biological active peptide. (Biotin-labeled HY-P1097)
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties[1].
Isorauhimbine is an alkaloid, can be isolated from R. serpentina[1].
Gamma-linolenic acid is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from human milk and several botanical seed oils. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease[1].
Isotocin ((Ser4,Ile8)-Oxytocin) is a biologically active peptide.
Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment[1].
p-Azoxyanisole-d6 is the deuterium labeled p-Azoxyanisole[1].
Carpalasionin is a natural product derived from Rabdosia serra. Rabdosia serra is an important component of Chinese herbal teas, traditionally used to treat hepatitis, jaundice, cholecystitis and colitis[1].
GBT 440 (Voxelotor) is an orally bioavailable modulator of sickle cell hemoglobin.
Parvisoflavanone is an isoflavanone that can be isolated from Mucuna pruriens[1].
Tetramethyl-ammonium Bromide-d12 is the deuterium labeled TMAB[1].
Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab (MCLA-117) kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research[1].
Monoethyl phthalate-d4 is the deuterium labeled Monoethyl phthalate[1]. Monoethyl phthalate is a metabolite of diethyl phthalate. Monoethyl phthalate acts as a urinary biomarker of phthalates exposure indicating the risks of thyroid cancer and benign nodule[2][3].
Tetradecyl sulfate sodium, a detergent sclerosant, is widely used agent for esophageal varices and varicose veins[1].
Fmoc-Pro-Pro-OH is a proline derivative[1].