Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

beflubutamid

Beflubutamid is a chiral soil herbicide against dicotyledonous weeds in cereals[1].

  • CAS Number: 113614-08-7
  • MF: C18H17F4NO2
  • MW: 355.327
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 496.6±45.0 °C at 760 mmHg
  • Melting Point: 75 °C
  • Flash Point: 254.1±28.7 °C

Methyl D-alanylglycinate

Methyl D-alanylglycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 67706-14-3
  • MF: C6H12N2O3
  • MW: 160.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7'-Hydroxy ABA-d2

7'-Hydroxy ABA-d2 is the deuterium labeled 7'-Hydroxy ABA[1].

  • CAS Number: 865875-19-0
  • MF: C15H18D2O5
  • MW: 282.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sinapultide

Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement[1].

  • CAS Number: 138531-07-4
  • MF: C126H238N26O22
  • MW: 2469.399
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 2047.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1191.9±34.3 °C

Skimmin

Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].

  • CAS Number: 93-39-0
  • MF: C15H16O8
  • MW: 324.28
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 632.0±55.0 °C at 760 mmHg
  • Melting Point: 221-222ºC
  • Flash Point: 239.3±25.0 °C

Ac-Ile-Tyr(PO3H2)-Gly-Glu-Phe-NH2 ammonium salt

p60c-src substrate II, phosphorylated is a pentapeptide. p60c-src substrate II, phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations[1].

  • CAS Number: 284660-72-6
  • MF: C30H41N6O10P
  • MW: 676.65500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Valrocemide

Valrocemide (TV1901) is a promising antiepileptic drug candidate that shows a broad spectrum of anticonvulsant activity.

  • CAS Number: 92262-58-3
  • MF: C10H20N2O2
  • MW: 200.27800
  • Catalog: Neurological Disease
  • Density: 0.997
  • Boiling Point: 417.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 206.3ºC

Mesembrenone

Mesembrenone is an alkaloid compound isolated from Narcissus Pallidulus[1].

  • CAS Number: 468-54-2
  • MF: C17H21NO3
  • MW: 287.35
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 383.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 186.0±27.9 °C

Phosphorylase b

Phosphorylase b is one of the two forms of phosphorylase present in skeletal muscle. The other is Phosphorylase a, which can be transformed into one another. The conversion process requires the addition of divalent metal ions and ATP[1].

  • CAS Number: 9012-69-5
  • MF: C8H8O3
  • MW: 152.147
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 308.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 123.3±13.3 °C

1-Methyl-2, 8-dihydroxy3-carboxy-9, 10-anthraquinone

1-Methyl-2, 8-dihydroxy3-carboxy-9, 10-anthraquinone (compound 2) is compound isolated from the roots of Rheum palmatum[1].

  • CAS Number: 1401414-53-6
  • MF: C16H10O6
  • MW: 298.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Notoginsenoside T5

Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng[1].

  • CAS Number: 769932-34-5
  • MF: C41H68O12
  • MW: 752.971
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 857.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 472.2±34.3 °C

GR148672X

GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2.

  • CAS Number: 263890-70-6
  • MF: C15H11F3N2O2S
  • MW: 340.320
  • Catalog: Cardiovascular Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 394.6±52.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.4±30.7 °C

Z-Phe-Arg-AMC · HCl

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].

  • CAS Number: 65147-22-0
  • MF: C33H36N6O6
  • MW: 612.68
  • Catalog: Others
  • Density: 1.32 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Custirsen

Custirsen is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.

  • CAS Number: 890056-27-6
  • MF: C231H312N78O119P20S20
  • MW:
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Epoprostenol sodium

Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH)[1]. Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation[2].

  • CAS Number: 61849-14-7
  • MF: C20H31NaO5
  • MW: 374.447
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: 530.2ºC at 760mmHg
  • Melting Point: 168-170 °C
  • Flash Point: 182.1ºC

Alteplase

Alteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters[1].

  • CAS Number: 105857-23-6
  • MF:
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GRK6-IN-2

GRK6-IN-2 (compound 10a) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) with an IC50 of 120 nM. GRK6 is a critical kinase required for the survival of multiple myeloma (MM) cells. GRK6-IN-2 has the potential for the research of multiple myeloma[1].

  • CAS Number: 2677786-27-3
  • MF: C21H21FN6
  • MW: 376.43
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-(3',6'-bis(ethylaMino)-2',7'-diMethyl-3- oxospiro[isoindoline-1,9'-xanthene]-2-yl)-3- phenylurea

1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea (compound 1a) can be used as a fast-responsive fluorescent gold ion probe for detection of gold ions in water and synthetic products[1].

  • CAS Number: 957493-98-0
  • MF: C33H33N5O3
  • MW: 547.64682
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Flavanone hydrazone

Flavanone hydrazine is a potent non-steroidal anti-inflammatory agent. Flavanone hydrazine effectively inhibits lens protein-induced ocular inflammation[1].

  • CAS Number: 1692-46-2
  • MF: C15H14N2O
  • MW: 238.28400
  • Catalog: Inflammation/Immunology
  • Density: 1.21g/cm3
  • Boiling Point: 425.2ºC at 760 mmHg
  • Melting Point: 110-112ºC
  • Flash Point: 210.9ºC

tribenuron

Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed[1].

  • CAS Number: 106040-48-6
  • MF: C14H15N5O6S
  • MW: 381.36400
  • Catalog: Others
  • Density: 1.513 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

29-Nor-20-oxolupeol

29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM[1].

  • CAS Number: 19891-85-1
  • MF: C29H48O2
  • MW: 428.690
  • Catalog: Neurological Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 503.5±23.0 °C at 760 mmHg
  • Melting Point: 237-239℃
  • Flash Point: 213.3±15.2 °C

Fmoc-Lys(Z)-OH

Fmoc-Lys(Z)-OH is a lysine derivative[1].

  • CAS Number: 86060-82-4
  • MF: C29H30N2O6
  • MW: 502.558
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 751.2±60.0 °C at 760 mmHg
  • Melting Point: 105-115ºC
  • Flash Point: 408.1±32.9 °C

Boc-Gly-OH

Boc-Glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 4530-20-5
  • MF: C7H13NO4
  • MW: 175.182
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 315.9±25.0 °C at 760 mmHg
  • Melting Point: 86-89 °C(lit.)
  • Flash Point: 144.9±23.2 °C

N-Demethyl-α-obscurine

N-Demethyl-α-obscurine, a lycodine-type Lycopodium alkaloid, is isolated from Lycopodii Herba[1].

  • CAS Number: 34399-44-5
  • MF: C16H24N2O
  • MW: 260.375
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 488.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.7±28.9 °C

Fmoc-Gln-OH

Fmoc-L-glutamine is a glutamine derivative[1].

  • CAS Number: 71989-20-3
  • MF: C20H20N2O5
  • MW: 368.383
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 699.8±55.0 °C at 760 mmHg
  • Melting Point: 220 °C (dec.)(lit.)
  • Flash Point: 377.1±31.5 °C

Tirapazamine

Tirapazamine is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death.

  • CAS Number: 27314-97-2
  • MF: C7H6N4O2
  • MW: 178.148
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 493.6±28.0 °C at 760 mmHg
  • Melting Point: 220ºC
  • Flash Point: 252.3±24.0 °C

Rhodiocyanoside A

Rhodiocyanoside A is found to show antiallergic activity in a passive cutaneous anaphylaxis test in rat[1].

  • CAS Number: 168433-86-1
  • MF: C11H17NO6
  • MW: 259.26
  • Catalog: Inflammation/Immunology
  • Density: 1.4g/cm3
  • Boiling Point: 533.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 276.3ºC

Fmoc-Asp-Obzl

Fmoc-Asp-Obzl is an aspartic acid derivative[1].

  • CAS Number: 86060-83-5
  • MF: C26H23NO6
  • MW: 445.464
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 683.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 367.3±31.5 °C

n-heptadecane-d36

N-heptadecane-d36 is the deuterium labeled N-heptadecane[1].

  • CAS Number: 39756-35-9
  • MF: C17D36
  • MW: 276.69000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AGI-25696

AGI-25696 is a methionine adenosyltransferase 2A (MATA2 ) inhibitors useful for treatment of cancer. AGI-25696 blocks growth of MTAP-deleted tumors in vivo.

  • CAS Number: 2201066-35-3
  • MF: C27H18N4O
  • MW: 414.46
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A