Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2,3,5-trimethylphenol-d11

2,3,5-Trimethylphenol-d11 is the deuterium labeled 2,3,5-Trimethylphenol[1].

  • CAS Number: 362049-46-5
  • MF: C9HD11O
  • MW: 147.25900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MK-6240

MK-6240 is a positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs.

  • CAS Number: 1841078-87-2
  • MF: C16H11FN4
  • MW: 278.28
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-CFDA,AM

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1].

  • CAS Number: 124412-00-6
  • MF: C28H20O11
  • MW: 532.45200
  • Catalog: Others
  • Density: 1.51g/cm3
  • Boiling Point: 737ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 312.7ºC

(+/-)-1,2-bis(palmitoyloxy)-3-(dimethylamino)propane

16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery[1].

  • CAS Number: 96326-74-8
  • MF: C37H73NO4
  • MW: 595.98000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1-(2H4)Cyclopropanedicarboxylic acid

Cyclopropane-1,1-dicarboxylic acid-d4 is the deuterium labeled Cyclopropane-1,1-dicarboxylic acid[1].

  • CAS Number: 136503-99-6
  • MF: C5H2D4O4
  • MW: 134.123
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 371.3±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.5±19.7 °C

Fucoxanthin

Fucoxanthin is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities.

  • CAS Number: 3351-86-8
  • MF: C42H58O6
  • MW: 676.922
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 786.5±60.0 °C at 760 mmHg
  • Melting Point: 166-168ºC
  • Flash Point: 228.5±26.4 °C

(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate

(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC50 value of 23.9 µg/mL. Antiobesity Effect[1].

  • CAS Number: 201012-14-8
  • MF: C17H16O5
  • MW: 300.31
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Thr(TBDMS)-OH

Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted therapy[1].

  • CAS Number: 146346-82-9
  • MF: C25H33NO5Si
  • MW: 455.61900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 577.2±50.0°C
  • Melting Point: N/A
  • Flash Point: N/A

F 16915

F 16915 is a docosahexaenoic acid derivative which can prevent heart failure-induced atrial fibrillation.

  • CAS Number: 92510-91-3
  • MF: C28H37NO2
  • MW: 419.60
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cauloside F

Cauloside F is a triterpenoid saponin isolated from Clematis akebioides.

  • CAS Number: 60451-47-0
  • MF: C59H96O27
  • MW: 1237.377
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dl-3-hydroxynorvaline

DL-3-Hydroxynorvaline is a valine derivative[1].

  • CAS Number: 2280-42-4
  • MF: C5H11NO3
  • MW: 133.14600
  • Catalog: Others
  • Density: 1.237g/cm3
  • Boiling Point: 328.4ºC at 760mmHg
  • Melting Point: 231.2℃
  • Flash Point: 152.4ºC

Escin IIb

Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals[1]. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions[2].

  • CAS Number: 158800-83-0
  • MF: C54H84O23
  • MW: 1101.231
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1111.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 305.5±27.8 °C

Diethyl 2,4-pyridinedicarboxylate

Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].

  • CAS Number: 41438-38-4
  • MF: C11H13NO4
  • MW: 223.23
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 330.9±22.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 153.9±22.3 °C

3'-Mant-GDP

3'-Mant-GDP is a nucleoside compound and a derivative of guanosine diphosphate[1].

  • CAS Number: 91828-87-4
  • MF: C18H22N6O12P2
  • MW: 576.34800
  • Catalog: Others
  • Density: 2.07g/cm3
  • Boiling Point: 978.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 545.6ºC

(R)-N-Boc-1-Naphthylalanine

(R)-2-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid is an alanine derivative[1].

  • CAS Number: 76932-48-4
  • MF: C18H21NO4
  • MW: 315.364
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 512.2±43.0 °C at 760 mmHg
  • Melting Point: 145-148 °C(lit.)
  • Flash Point: 263.6±28.2 °C

(5S,6S,7S,8R)-8-Chloro-5,6,7-trihydroxy-2-phenylethyl-5,6,7,8-tetrahydro-4H-chromen-4-one

8-Chloro-2-(2-phenylethyl)-5,6,7-trihydroxy-5,6,7,8-tetrahydrochromone, a chromone derivative, can be found in MeOH extract of withered wood of Aquilaria sinensis[1].

  • CAS Number: 626236-06-4
  • MF: C17H17O5Cl
  • MW: 336.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3-Dihydroxyacetone

1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol over Gluconobacter oxydans[1].

  • CAS Number: 96-26-4
  • MF: C3H6O3
  • MW: 90.078
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 213.7±15.0 °C at 760 mmHg
  • Melting Point: 75-80 °C
  • Flash Point: 97.3±16.9 °C

Digoxigenin

Digoxigenin is a hapten, a small molecule with high antigenicity, that is used in many molecular biology applications, as an alternative probe labeling for in situ hybridization

  • CAS Number: 1672-46-4
  • MF: C23H34O5
  • MW: 390.51300
  • Catalog: Inflammation/Immunology
  • Density: 1.297 g/cm3
  • Boiling Point: 589.4ºC at 760 mmHg
  • Melting Point: 222 °C(lit.)
  • Flash Point: 203ºC

4-Hydroxycoumarin

4-Hydroxycoumarin, a coumarin derivative, is one of the most versatile heterocyclic scaffolds and is frequently applied in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin derivatives are employed as the anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors and tyrosine kinase inhibitors[1].

  • CAS Number: 1076-38-6
  • MF: C9H6O3
  • MW: 162.142
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 352.4±42.0 °C at 760 mmHg
  • Melting Point: 211-213 °C(lit.)
  • Flash Point: 165.4±20.7 °C

H-Glu-Val-OH

H-Glu-Val-OH is a biologically active peptide.

  • CAS Number: 5879-06-1
  • MF: C10H18N2O5
  • MW: 246.26000
  • Catalog: Others
  • Density: 1.272g/cm3
  • Boiling Point: 550.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 286.8ºC

H-Nle-Arg-Phe-NH2 acetate salt

Nle-Arg-Phe-NH2 (acetate) is a tripeptide compound, usually in the form of acetate[1].

  • CAS Number: 104809-29-2
  • MF: C25H43N7O7
  • MW: 553.65
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PEG 12 cetostearyl ether

PEG 12 cetostearyl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 13149-83-2
  • MF: C40H82O13
  • MW: 771.07
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-hydroxy-3-(4-methoxyphenyl)-7-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxy-chromen-4-one

Kakkanin comes from the roots of O. henryi and can be used for the research of anti-inflammatory[1].

  • CAS Number: 63770-91-2
  • MF: C27H30O14
  • MW: 578.51900
  • Catalog: Inflammation/Immunology
  • Density: 1.66g/cm3
  • Boiling Point: 891.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 297ºC

Pyrithioxin dihydrochloride

Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

  • CAS Number: 10049-83-9
  • MF: C16H22Cl2N2O4S2
  • MW: 441.393
  • Catalog: Neurological Disease
  • Density: 1.448g/cm3
  • Boiling Point: 742.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 403ºC

Xanthinin

Xanthinin is a plant growth-regulating compound from Xanthium pennsylvanicum. I[1].

  • CAS Number: 153483-31-9
  • MF: C17H22O5
  • MW: 306.354
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 476.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.6±28.8 °C

Exo1

Exo1 is a chemical inhibitor of the exocytic pathway.

  • CAS Number: 75541-83-2
  • MF: C15H12FNO3
  • MW: 273.25900
  • Catalog: Others
  • Density: 1.298 g/cm3
  • Boiling Point: 333.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 155.8ºC

AV45

Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18[1].

  • CAS Number: 938435-69-9
  • MF: C20H25FN2O3
  • MW: 360.422
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 524.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 271.1±30.1 °C

(R)-ketorolac

(R)-Ketorolac is the R-enantiomer of Ketorolac, shows potent analgesic activity, reduces ulcerogenic potential. (R)-Ketorolac is inactive on COX[1].

  • CAS Number: 66635-93-6
  • MF: C15H13NO3
  • MW: 255.269
  • Catalog: Neurological Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 493.2±40.0 °C at 760 mmHg
  • Melting Point: 163-170°C
  • Flash Point: 252.1±27.3 °C

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma[1].

  • CAS Number: 98014-38-1
  • MF: C45H68NO8P
  • MW: 781.99700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Evonimine

Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis[1].

  • CAS Number: 41758-69-4
  • MF: C38H47NO18
  • MW: 805.77600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 148-153 °C
  • Flash Point: N/A