Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

N-Acetyl-4-hydroxy-L-proline

N-Acetyl-4-hydroxy-L-proline (cis- and trans- mixture) is a proline derivative[1].

  • CAS Number: 926905-71-7
  • MF: C7H11NO4
  • MW: 173.167
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 442.1±45.0 °C at 760 mmHg
  • Melting Point: 131 °C
  • Flash Point: 221.2±28.7 °C

Lemzoparlimab

Lemzoparlimab (TJ011133; TJC4) is a humanized anti-CD47 IgG4 antibody. Lemzoparlimab has a strong anti-tumor activity[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Competence-Stimulating Peptide-2 (CSP-2)

Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide produced by Streptococcus pneumoniae. ComD2 is a compatible receptor of Competence-Stimulating Peptide-2 (CSP-2) with an EC50 value of 50.7 nM[1].

  • CAS Number: 1174553-84-4
  • MF: C101H172N28O23S
  • MW: 2178.69
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Naringenin-4',7-diacetate

Naringenin-4',7-diacetate (compound 13) is a pyrrolidinoflavanne isolated from the fruits of Vocbysiaguianensis[1].

  • CAS Number: 18196-13-9
  • MF: C19H16O7
  • MW: 356.326
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 578.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.5±23.6 °C

4-Methoxy(O-2H5)phenol

Mequinol-d4 is the deuterium labeled Mequinol[1]. Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis. Mequinol is used for skin depigmentation[2].

  • CAS Number: 126840-02-6
  • MF: C7H3D5O2
  • MW: 129.168
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 243.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 120.8±4.8 °C

DMPA-d7

DMPA-d7 is the deuterium labeled DMPA[1].

  • CAS Number: 1219802-03-5
  • MF: C5H10O4
  • MW: 134.130
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 366.7±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.7±21.6 °C

Humantenmine

Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2].

  • CAS Number: 82354-38-9
  • MF: C19H22N2O3
  • MW: 326.390
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 463.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.2±31.5 °C

Fmoc-Ser(Ac)-OH

Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor[1].

  • CAS Number: 171778-17-9
  • MF: C20H19NO6
  • MW: 369.368
  • Catalog: Infection
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 611.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323.4±31.5 °C

Geoside

Geoside (Gein) is a natural compound isolated from stevia rebaudiana.

  • CAS Number: 585-90-0
  • MF: C21H30O11
  • MW: 458.45600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

C.I. 74240

Alcian Blue 8GX is a cationic copper phthalocyanine dye well-known to bind to glycoproteins and to glucosaminoglycans[1].

  • CAS Number: 33864-99-2
  • MF: C38H30CuN10S+
  • MW: 722.32300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 148ºC
  • Flash Point: N/A

β-Bisabolene

β-Bisabolene is a sesquiterpene isolated from opoponax (Commiphora guidotti). β-Bisabolene, an anti-cancer agent, can be used for the study of breast cancer[1].

  • CAS Number: 495-61-4
  • MF: C15H24
  • MW: 204.35100
  • Catalog: Others
  • Density: 0.854g/cm3
  • Boiling Point: 275.441ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 109.79ºC

Hemagglutinin (48-68)

Hemagglutinin (48-68) is the 48-68 fragment of influenza virus hemagglutinin. Hemagglutinin (48-68) can induce proliferation of the peptide specific T-cell clones[1].

  • CAS Number: 115721-95-4
  • MF: C97H163N29O32S2
  • MW: 2311.64
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Catalponol

Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].

  • CAS Number: 34168-56-4
  • MF: C15H18O2
  • MW: 230.302
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 369.8±31.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 157.8±17.4 °C

GK60

GK60 is a carboxyl nicotine hapten that can be used in the study of nicotine dependence[1].

  • CAS Number: 250683-13-7
  • MF: C13H14N2O2
  • MW: 230.26
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Amino-2-methylpropan-2-ol-d6

1-Amino-2-methylpropan-2-ol-d6 is the deuterium labeled 1-Amino-2-methylpropan-2-ol[1].

  • CAS Number: 1953176-77-6
  • MF: C4H5D6NO
  • MW: 95.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CyaonosideA

3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC50s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC50 of 20.4 μM[1].

  • CAS Number: 108352-70-1
  • MF: C16H14O4
  • MW: 270.28
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pheromonotropin (pseudaletia separata)

Pheromonotropin (Pseudaletia separata) (Pss-PT) is an armyworm (Pseudaletia separata) pheromone with the C-terminal pentapeptide FXPRL-amide. Pheromonotropin (Pseudaletia separata) belongs to the PK/PBAN family and stimulates sex pheromone biosynthesis in moths, mediating feeding (intestinal muscle contraction), development (embryonic diapause, pupal diapause, and pupation), and defense against natural enemy insects wait[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Somatostatin-28 (1-12)

Somatostatin-28 (1-12) is a somatostatin fragment that is monitored in brain tissue to track processing of somatostatin.

  • CAS Number: 81286-16-0
  • MF: C49H81N17O19S
  • MW: 1244.335
  • Catalog: Peptides
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Bromo-3-indolyl β-D-galactopyranoside

5-Bromo-3-indolyl β-D-galactopyranoside (Bluo-Gal) is a chromogenic substrate to detect bacterial β-D-galactosidase activity. 5-Bromo-3-indolyl β-D-galactopyranoside is used both to recognize labelled myofibers, and beta-gal positive organelles inside single myofibers[1].

  • CAS Number: 97753-82-7
  • MF: C14H16BrNO6
  • MW: 374.184
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 646.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 344.9±31.5 °C

Z-Asp(OBzl)-OH

Z-Asp(OBzl)-OH is an aspartic acid derivative[1].

  • CAS Number: 3479-47-8
  • MF: C19H19NO6
  • MW: 357.357
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 587.4±50.0 °C at 760 mmHg
  • Melting Point: 105-107ºC
  • Flash Point: 309.1±30.1 °C

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

  • CAS Number: 97337-37-6
  • MF: C11H12ClN3O3
  • MW: 269.68428
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aucuparin

Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (BLM)-induced lung fibrosis mouse model. Anti-inflammatory activity[1][2].

  • CAS Number: 3687-28-3
  • MF: C14H14O3
  • MW: 230.25900
  • Catalog: Inflammation/Immunology
  • Density: 1.144g/cm3
  • Boiling Point: 349.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.1ºC

N-Boc-D-methionine

Boc-D-Met-OH is a Methionine (HY-13694) derivative[1].

  • CAS Number: 5241-66-7
  • MF: C10H19NO4S
  • MW: 249.327
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 415.5±40.0 °C at 760 mmHg
  • Melting Point: 47-50ºC
  • Flash Point: 205.1±27.3 °C

1,1-Dioxothiolan-d8

1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan[1].

  • CAS Number: 51219-88-6
  • MF: C4D8O2S
  • MW: 128.21900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 283-285ºC
  • Melting Point: 25-27ºC
  • Flash Point: 177ºC

nalpha-fmoc-l-serine tert-butyl ester

Fmoc-Ser-OtBu is a serine derivative[1].

  • CAS Number: 110797-35-8
  • MF: C22H25NO5
  • MW: 383.43800
  • Catalog: Others
  • Density: 1.217g/cm3
  • Boiling Point: 588.356ºC at 760 mmHg
  • Melting Point: 127ºC
  • Flash Point: 309.627ºC

Sorbinicate

Sorbinicate, a derivative of nicotinic acid, exerts a favourable influence on blood rheology and platelet function[1].

  • CAS Number: 6184-06-1
  • MF: C42H32N6O12
  • MW: 812.73600
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: 965.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 537.7ºC

4-(3-Hydroxyprop-1-en-1-yl)phenol

p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. p-Coumaryl alcohol has inhibitory effect during the autoxidation of methyl linoleate[1][2].

  • CAS Number: 3690-05-9
  • MF: C9H10O2
  • MW: 150.17
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 323.5±22.0 °C at 760 mmHg
  • Melting Point: 124°C(lit.)
  • Flash Point: 162.7±16.9 °C

Camptothecin analog-1

Camptothecin analog-1 (Comp 166) is a camptothecin analog[1].

  • CAS Number: 2873460-51-4
  • MF: C23H23FN4O6S
  • MW: 502.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Caspase-3 Substrate

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.

  • CAS Number: 958001-92-8
  • MF: C30H38N6O12
  • MW: 674.656
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1211.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 686.3±34.3 °C

Taxuyunnanine

Paclitaxel C is a compound that can be found in taxus cutting[1].

  • CAS Number: 153415-45-3
  • MF: C46H57NO14
  • MW: 847.94
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 932.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 517.6±34.3 °C