Goniotriol(compound 2) is a styrylpyronethat can be found in Goniothalamus amuyon. Goniotriolshows cytotoxicity[1].
Isotachioside is a aromatic glucoside that can be found in Berchemia racemosa[1].
PAT-1251 is a potent, selective and oral Lysyl Oxidase-Like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 has entered clinical development with the potential to treat a number of fibrotic diseases.
Dihydrobaicalin is a flavonoid glycoside, which can be isolated from American skullcap (Scutellaria lateriflora L.)[1].
Aceratioside, a tetralin glucoside, is a weakly cytostatic constituent. Aceratioside is an antineoplastic agent[1].
N-(3-Nitro-2-pyridinesulfenyl)-L-aspartic acid β-t-butyl ester is an aspartic acid derivative[1].
MRT-2359 is an orally active and potent degrader of GSPT1 with anti-tumor activity. MRT-2359 also inhibits the growth of resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells. MRT-2359 exhibits preferential activity in MYC-driven cell lines, such as N- and L-MYC high NSCLC and SCLC patient-derived xenografts (PDXs)[1].
TMPA is an antagonist of nuclear receptor Nur77 and LKB1 interaction.
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish[1].
(1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum[1].
Benzyl lactate is a kind lactate ester[1].
Isolugrandoside is a nature product. Isolugrandoside can be isolated from Digitalis davisiana Heywood[1].
KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule[1][2].
1,4-Dibromo-butane-1,1,2,2,3,3,4,4-d8 is the deuterium labeled 1,4-Dibromo-butane[1].
N-ε-propargyloxycarbonyl-L-lysine hydrochloride is a modified amino acid (L-lysine) for cancer therapy development[1].
RXFP1 receptor agonist-6 (Example 7) is a RXFP1 receptor agonist. RXFP1 receptor agonist-6 inhibits cAMP production in HEK293 cells stably expressing human RXFP1, with an EC50 value of 12 nM[1].
Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy[1].
DPLG3 is a specific chymotryptic-like β5i subunits inhibitor. DPLG3 inhibits mouse i-20S with IC50 of 9.4 nM. DPLG3 can be used for immune disease research[1].
Angiotensinogen (1-14) porcine is a polypeptide, which is the N-terminal fragment of angiotensinogen, including amino acid residues 1 to 14[1].
Iodochloromethane-d2 is the deuterium labeled Iodochloromethane[1].
4-Hydroxyacetophenone (P-hydroxyacetophenone) is a key hepatoprotective and choleretic compound in Artemisia capillaris and A. morrisonensis, also has an anti-hepatitis B virus effect and anti-inflammatory effect[1].
Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46[1][2][3].
T807 a novel tau positron emission tomography (PET) tracer.
Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, sedative, and tranquilizing agent[1].
(tert-Butoxycarbonyl)-L-arginine hydrochloride is an arginine derivative[1].
(Rac)-CPI-203 is a racemate of CPI-203 (HY-15846) (BET bromodomain inhibitor)[1]
Boc-Met-OSu is a Methionine (HY-13694) derivative[1].
Boc-Ala-Ala-pNA is a serine peptidase[1]
Methyl behenate (Methyl docosanoate) is a naturally fatty acid methyl ester isolated from the plant of Aspidopterys obcordata Lemsl[1].