Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

o-Orsellinic acid

Orsellinic acid is a compound produced by Lecanoric acid treated with alcohols. Lecanoric acid is a lichen depside isolated from a Parmotrema tinctorum specimen[1].

  • CAS Number: 480-64-8
  • MF: C8H8O4
  • MW: 168.147
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 391.4±22.0 °C at 760 mmHg
  • Melting Point: 173-174ºC
  • Flash Point: 204.7±18.8 °C

Ipfencarbazone

Ipfencarbazone is a substance being developed for the control of weeds such as watergrass in rice; herbicide agent.

  • CAS Number: 212201-70-2
  • MF: C18H14Cl2F2N4O2
  • MW: 427.23200
  • Catalog: Others
  • Density: 1.46g/cm3
  • Boiling Point: 494.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 252.8ºC

Phthalic acid bis(3,7-dimethyloctyl) ester-d4

Phthalic acid bis(3,7-dimethyloctyl) ester-d4 is the deuterium labeled Phthalic acid bis(3,7-dimethyloctyl) ester[1].

  • CAS Number: 1398065-81-0
  • MF: C28H42D4O4
  • MW: 450.687
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 398.8±10.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 212.4±8.5 °C

ARLAMOL(TM) E

Polyoxypropylene stearyl ether can be used as an excipient, such as surfactant, softener, lubricating, wetting, plasticizing, solubilizing and dispersing properties. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 25231-21-4
  • MF: (C3H6O)nC18H38O
  • MW: 328.57300
  • Catalog: Others
  • Density: 0.865g/cm3
  • Boiling Point: 423.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 157.1ºC

JHU395

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) prodrug. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST[1].

  • CAS Number: 2079938-92-2
  • MF: C22H29N3O7
  • MW: 447.48
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,7-dimethoxy-2,2-dimethylchromene

5,7-Dimethoxy-2,2-dimethylchromene is a synthetic precocenoid, has potential insect control function. 5,7-Dimethoxy-2,2-dimethylchromene induces loss of pigmentation in hatching larvae of shield bug (Eurgaster integriceps)[1][2].

  • CAS Number: 21421-66-9
  • MF: C13H16O3
  • MW: 220.26400
  • Catalog: Others
  • Density: 1.063g/cm3
  • Boiling Point: 325.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Fargesin

Fargesin is a bioactive neolignan isolated from magnolia plants,with antihypertensive and anti-inflammatory effects[1][2][3].

  • CAS Number: 31008-19-2
  • MF: C21H22O6
  • MW: 370.396
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 506.4±50.0 °C at 760 mmHg
  • Melting Point: 132.0 to 136.0 °C
  • Flash Point: 208.9±30.0 °C

P-BP-SFAC

P-BP-SFAC is a fluorescence molecule. P-BP-SFAC exhibits an apparent absorption band with a peak at about 377 nm, indicative of a stronger ICT effect[1].

  • CAS Number: 2247391-82-6
  • MF: C38H25NO
  • MW: 511.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Butibufen

Butibufen is a non-steroidal compound. Butibufen shows analgesic and antipyretic properties. Butibufen can be used for the research of inflammation[1][2].

  • CAS Number: 55837-18-8
  • MF: C14H20O2
  • MW: 220.30700
  • Catalog: Inflammation/Immunology
  • Density: 1.015g/cm3
  • Boiling Point: 335.1ºC at 760mmHg
  • Melting Point: 51-53°
  • Flash Point: 232.1ºC

H-Ser-Gln-OH

H-Ser-Gln-OH is a biologically active peptide.

  • CAS Number: 94421-66-6
  • MF: C8H15N3O5
  • MW: 233.22200
  • Catalog: Others
  • Density: 1.423±0.06 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: 749.7±60.0 °C (760 mmHg)
  • Melting Point: N/A
  • Flash Point: N/A

Brevianamide F

Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.Brevianamide F possess interesting breast cancer resistance protein inhibitory activity.[1] brevianamide F once used as aromatic substrate. [2]

  • CAS Number: 38136-70-8
  • MF: C16H17N3O2
  • MW: 283.32500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 633.2°C
  • Melting Point: N/A
  • Flash Point: N/A

Milpocitide

Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1)[1].

  • CAS Number: 2643306-81-2
  • MF: C255H413N63O86S6
  • MW: 5929.75
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Keto petromyzonol

3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey[1].

  • CAS Number: 359436-56-9
  • MF: C24H40O4
  • MW: 392.572
  • Catalog: Endocrinology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 543.7±50.0 °C at 760 mmHg
  • Melting Point: 195ºC
  • Flash Point: 296.7±26.6 °C

Dimethyl pimelate-d4

Dimethyl pimelate-d4 is the deuterium labeled Dimethyl pimelate[1].

  • CAS Number: 120811-82-7
  • MF: C9H12D4O4
  • MW: 192.246
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 250.3±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 105.4±16.9 °C

α-Lactose

α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate[1][2].

  • CAS Number: 14641-93-1
  • MF: C12H22O11
  • MW: 342.29600
  • Catalog: Others
  • Density: 1.76 g/cm3
  • Boiling Point: 667.9ºC at 760 mmHg
  • Melting Point: 201-202ºC
  • Flash Point: 357.8ºC

Terbutryn-d5

Terbutryn-d5 is the deuterium labeled Terbutryn[1].

  • CAS Number: 1219804-47-3
  • MF: C10H14D5N5S
  • MW: 246.387
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 401.1±28.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.4±24.0 °C

Uridylate kinase

Uridylate kinase is a member of the nucleoside mono-phosphate (NMP) kinase family and catalyzes the reaction ATP+NMP?ADP+NDP with moderate specificity for UMP[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Antioxidantagent-4

Antioxidant agent-4 (Compound 2) is an effective antioxidant molecule with antilipid peroxidative activity[1].

  • CAS Number: 50901-34-3
  • MF: C8H8O4
  • MW: 168.14700
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Polzastobart

Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor[1].

  • CAS Number: 2640981-19-5
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nitrilotriacetic acid-d9

Nitrilotriacetic acid-d9 is the deuterium labeled Nitrilotriacetic acid[1]. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[2].

  • CAS Number: 807630-34-8
  • MF: C6H9NO6
  • MW: 191.13900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Futoquinol

Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities[1].

  • CAS Number: 28178-92-9
  • MF: C21H22O5
  • MW: 354.396
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 515.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 225.5±30.2 °C

1-(Triphenylmethyl)-L-histidine methyl ester monohydrochloride

H-His(trt)-OMe hydrochloride is a histidine derivative[1].

  • CAS Number: 32946-56-8
  • MF: C26H26ClN3O2
  • MW: 447.957
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GPRP acetate

GPRP acetate is fibrinogen-related peptide, which inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Sequence: Gly-Pro-Arg-Pro.

  • CAS Number: 157009-81-9
  • MF: C20H35N7O7
  • MW: 485.535
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Membrane-Permeable Sequence, MPS

Membrane-Permeable Sequence, MPS is a cell-penetrating peptide (CPP). Membrane-Permeable Sequence, MPS can be used for the research of membrane crossing mechanism[1].

  • CAS Number: 1231898-22-8
  • MF: C75H135N17O17
  • MW: 1546.98
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Tyr(Propargyl)-OH

H-D-Tyr(Propargyl)-OH is a click chemistry reagent containing an Azide[1].

  • CAS Number: 1170674-20-0
  • MF: C12H13NO3
  • MW: 219.236
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 396.0±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.3±27.9 °C

5-(N-Methyl-N-trifluoroacetyl)aminomethyl uridine

5-(N-Methyl-N-trifluoroacetyl)aminomethyl uridine is a nucleoside compound[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lethedioside A

Lethedioside A is an Enhancer of split 1 (Hes1) dimer inhibitor with an IC50 value of 9.5 μM[1].

  • CAS Number: 221289-31-2
  • MF: C29H34O15
  • MW: 622.57
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 890.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 290.5±27.8 °C

11β-HSD1-IN-1

11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain.

  • CAS Number: 1203956-47-1
  • MF: C18H14ClF4N3O
  • MW: 399.77
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Incensole

Incensole, a 14-membered diterpenoid, is isolated from both essential oils and resins of frankincense. Incensole has shown anti-inflammatory and anti-depression activities due to their ability to activate ion channels in the brain to alleviate anxiety or depression[1].

  • CAS Number: 22419-74-5
  • MF: C20H34O2
  • MW: 306.48300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bz-Arg-OEt��HCl

N-Benzoyl-L-arginine ethyl ester hydrochloride is an arginine derivative[1].

  • CAS Number: 2645-08-1
  • MF: C15H23ClN4O3
  • MW: 342.821
  • Catalog: Others
  • Density: 1.23g/cm3
  • Boiling Point: N/A
  • Melting Point: 128-130 °C
  • Flash Point: N/A