Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fmoc-Dap(Alloc)-OH

Fmoc-Dap(Alloc)-OH is an alanine derivative[1].

  • CAS Number: 188970-92-5
  • MF: C22H22N2O6
  • MW: 410.420
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 658.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 352.1±31.5 °C

Anti-inflammatory agent 30

Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity[1].

  • CAS Number: 2573174-21-5
  • MF: C25H26O12
  • MW: 518.47
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6'-O-β-D-Apiofuranosylsweroside

6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall[1].

  • CAS Number: 266678-59-5
  • MF: C21H30O13
  • MW: 490.455
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 800.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 276.6±27.8 °C

Dibromochloroacetaldehyde

Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity[1].

  • CAS Number: 64316-11-6
  • MF: C2HBr2ClO
  • MW: 236.29000
  • Catalog: Others
  • Density: 2.444g/cm3
  • Boiling Point: 129.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 32.3ºC

ADOS

ADOS(82692-96-4) is a biochemical reagent/chromogenic reagent.Molar absorptivity(pH10): ≥8,200(around 255 nm)Appearance: White or slightly brown powder

  • CAS Number: 82692-96-4
  • MF: C12H18NNaO5S
  • MW: 311.33
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 144 °C
  • Flash Point: N/A

(S)-Methyl 3-aMino-2-((tert-butoxycarbonyl)aMino)propanoate hydrochloride

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride is an alanine derivative[1].

  • CAS Number: 181228-33-1
  • MF: C9H19ClN2O4
  • MW: 254.71100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Octacosanol

1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function[1].

  • CAS Number: 557-61-9
  • MF: C28H58O
  • MW: 410.759
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 428.1±8.0 °C at 760 mmHg
  • Melting Point: 81-83°C
  • Flash Point: 135.3±6.0 °C

Malaoxon

Malaoxon is a pesticide metabolite. Malaoxon can induce cellular death in cultured human pulmonary cells. Malaoxon can be used for the research of pulmonary toxicity[1].

  • CAS Number: 1634-78-2
  • MF: C10H19O7PS
  • MW: 314.292
  • Catalog: Infection
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 376.0±52.0 °C at 760 mmHg
  • Melting Point: <20℃
  • Flash Point: 181.2±30.7 °C

IRF5-IN-1

IRF5-IN-1 (compound C5) is an IRF5 pathway-specific inhibitor. IRF5-IN-1 significantly reduces IRF5 nuclear translocation without affecting the activation of NF-κB p65. IRF5-IN-1 acts through SLC15A4 to selectively inhibit TLR7/8-induced IRF5 responses in cells[1].

  • CAS Number: 689270-18-6
  • MF: C27H33N3O2
  • MW: 431.57
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-O-(α-D-galactosyl)-N-hexacosanoylphytosphingosine

α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor)[1][2][3][4].

  • CAS Number: 158021-47-7
  • MF: C50H99NO9
  • MW: 858.322
  • Catalog: Cancer
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 939.8±65.0 °C at 760 mmHg
  • Melting Point: 190 °C
  • Flash Point: 522.2±34.3 °C

Boc-D-serine

(tert-Butoxycarbonyl)-D-serine is a serine derivative[1].

  • CAS Number: 6368-20-3
  • MF: C8H15NO5
  • MW: 205.208
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 385.1±37.0 °C at 760 mmHg
  • Melting Point: 91-95 ℃(lit.)
  • Flash Point: 186.7±26.5 °C

Rovanersen

Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cresyl Violet perchlorate

Cresyl Violet perchlorate is a red fluorescent stain, which can be used to stain neurons.

  • CAS Number: 41830-80-2
  • MF: C16H12ClN3O5
  • MW: 361.73700
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: 482.3ºC at 760mmHg
  • Melting Point: 331 - 333ºC
  • Flash Point: 245.5ºC

Fmoc-D-Arg(pbf)-OH

Fmoc-D-Arg(Pbf)-OH is an arginine derivative[1].

  • CAS Number: 187618-60-6
  • MF: C34H40N4O7S
  • MW: 648.769
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 94 to 98ºC
  • Flash Point: N/A

Arborescosidic acid

Arborescosidic acid (Deacetylalpinoside) is a carboxylated iridoid glucoside, that can be isolated from Veronica beccabunga (brooklime)[1].

  • CAS Number: 325798-51-4
  • MF: C16H22O10
  • MW: 374.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NH-3

NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment[1][2][3].

  • CAS Number: 447415-26-1
  • MF: C28H27NO6
  • MW: 473.52
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Trp-Ser-OH

N-L-Tryptophylserine is a biologically active peptide.

  • CAS Number: 133101-40-3
  • MF: C14H17N3O4
  • MW: 291.30200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CLIP 86-100

CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].

  • CAS Number: 648881-58-7
  • MF: C72H128N20O19S3
  • MW: 1674.10
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-O-B-D-GALACTOPYRANOSYL-D-GALACTOSE

6-O-β-D-Galactopyranosyl-D-galactose, a disaccharide, is a part of the polysaccharide main chain with β-(1→6)-glycoside bonds with a side chain bonded to the main one by the β-(1→3) bond[1].

  • CAS Number: 5077-31-6
  • MF: C12H22O11
  • MW: 342.29600
  • Catalog: Others
  • Density: 1.68g/cm3
  • Boiling Point: 774.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 288.9ºC

Dehydro-ZINC39395747

Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].

  • CAS Number: 433248-87-4
  • MF: C12H9N3O2S2
  • MW: 291.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PAMP-12(human, porcine) TFA

PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1].

  • CAS Number: 196305-05-2
  • MF: C77H119N25O14
  • MW: 1618.93
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fesomersen sodium

Fesomersen (sodium) is an antisense oligonucleotide designed to inhibit the production of Factor XI.

  • CAS Number: 2380288-85-5
  • MF: C296H434N82O156P20S13Na20
  • MW: 9113.01
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-Erysotramidine

Erysotramidine is an alkaloid that can be isolated from the stem barks of Erythrina stricta[1].

  • CAS Number: 52358-58-4
  • MF: C19H21NO4
  • MW: 327.37
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 565.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 296.0±30.1 °C

IDR 1002

IDR 1002 is an IPO-38 antibody marker protein. IDR1002 catalyzes the conversion of arginine to citrulline. IDR 1002 can be usedto study the role of citrullinated modification of protein in cancer biology[1].

  • CAS Number: 1224095-25-3
  • MF: C79H130N26O13
  • MW: 1652.04
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nurr1 agonist 4

Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1].

  • CAS Number: 87645-58-7
  • MF: C12H10O4
  • MW: 218.21
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-Undecyl β-D-maltopyranoside

n-Undecyl β-D-maltopyranoside is a malted glycoside.

  • CAS Number: 253678-67-0
  • MF: C23H44O11
  • MW: 496.59
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 696.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 374.9±31.5 °C

Mangafodipir (trisodium)

Mangafodipir is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver.

  • CAS Number: 140678-14-4
  • MF: C22H27MnN4Na3O14P2
  • MW: 757.32300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 1049.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 588.3ºC

1'-Hydroxymidazolam-13C3

1'-Hydroxymidazolam-13C3 is the 13C labeled 1'-Hydroxymidazolam[1].

  • CAS Number: 1189677-14-2
  • MF: C1513C3H13ClFN3O
  • MW: 344.745
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16:0 (Rac)-PC-d80

16:0 (Rac)-PC-d80 is deuterium labeled 16:0 (Rac)-PC.

  • CAS Number: 100412-79-1
  • MF: C40D80NO8P
  • MW: 814.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LGD-2226

LGD-2226 is a selective and orally active androgen receptor modulator with an EC50 of 0.2 nM and a Ki of 1.5 nM for human androgen receptor. LGD-2226 shows tissue selectivity in animal models, with reduced effects on prostate compared to muscle. LGD-2226 can be used for muscle wasting, osteoporosis and sexual dysfunction[1][2].

  • CAS Number: 328947-93-9
  • MF: C14H9F9N2O
  • MW: 392.22000
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A