Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

D-Lyxono-1,4-lactone

d-Lyxono-1,4-lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 15384-34-6
  • MF: C5H8O5
  • MW: 148.11
  • Catalog: Others
  • Density: 1.668g/cm3
  • Boiling Point: 364.319ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 162.791ºC

ERKtide

ERKtide is a biological active peptide. (ERKtide is a peptide substrate for ERK2. Extracellular regulated protein kinase 2 (ERK2) is a eukaryotic protein kinase whose activity is regulated by mitogenic stimuli.)

  • CAS Number: 287721-17-9
  • MF: C58H93N19O16
  • MW: 1312.48
  • Catalog: ERK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyr-Arg-Thr-Lys-Arg-AMC trifluoroacetate salt

Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors[1].

  • CAS Number: 155575-02-3
  • MF: C37H57N13O9
  • MW: 827.93
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dalcinonacog alfa

Dalcinonacog alfa is a recombinant FIX factor that can be used in the study of Haemophilia B[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Myriceric acid C

Myriceric acid C, a saturated fatty acid, is a natural product that can be isolated from Myrica cerifera[1].

  • CAS Number: 162059-94-1
  • MF: C48H60O10
  • MW: 796.984
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 890.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.3±27.8 °C

JNJ-54119936

JNJ-54119936 is a novel RORC inverse agonist (Kd=5.3 nM)[1][2].

  • CAS Number: 1599531-55-1
  • MF: C34H33ClN4O3
  • MW: 581.10
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isofutoquinol A

Isofutoquinol A is a neolignan that can be found in Piper futokadzura[1].

  • CAS Number: 62499-70-1
  • MF: C21H22O5
  • MW: 354.39600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chlorindanol

Chlorindanol is a new antiseptic agent.

  • CAS Number: 145-94-8
  • MF: C9H9ClO
  • MW: 168.62000
  • Catalog: Others
  • Density: 1.308g/cm3
  • Boiling Point: 290ºC at 760mmHg
  • Melting Point: 91-93ºC
  • Flash Point: 129.2ºC

6-TET phosphoramidite

6-TET phosphoramidite (5′-Tetrachlorofluorescein phosphoramidite) is a fluorescent dye that can be used for labeling an oligonucleotide with fluorescein[1].

  • CAS Number: 877049-90-6
  • MF: C46H54Cl4N3O10P
  • MW: 981.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 895.1±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Desbutyl Lumefantrine D9

Desbutyl Lumefantrine D9 is the deuterium labeled euterium labeled, which is a metabolite of Lumefantrine.

  • CAS Number: 1346606-35-6
  • MF: C26H15D9Cl3NO
  • MW: 481.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 65-72°C
  • Flash Point: N/A

Oct-3-enoic acid

Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 1577-19-1
  • MF: C8H14O2
  • MW: 142.19600
  • Catalog: Others
  • Density: 0.955g/cm3
  • Boiling Point: 244ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 141.3ºC

Solanidiene

Solanidiene (Solanthrene) is isolated from the leaves of S. tuberosum[1].

  • CAS Number: 26516-51-8
  • MF: C27H41N
  • MW: 379.62100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LPA2 antagonist 2

LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM, which is >480-fold more selective than LPA3 (IC50 of 13.85 μM)[1].

  • CAS Number: 36840-10-5
  • MF: C20H16N2O6
  • MW: 380.35100
  • Catalog: LPL Receptor
  • Density: 1.444±0.06 g/cm3(Predicted)
  • Boiling Point: 758.0±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate

DiI (DiIC18(3)) is a lipophilic membrane dye that diffuses laterally to stain the entire cell. DiI is excited to emit orange-red fluorescence. The fluorescence is weak in water but strong and photostable when incorporated into membranes.

  • CAS Number: 41085-99-8
  • MF: C59H97ClN2O4
  • MW: 933.86500
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 68ºC (dec.)(lit.)
  • Flash Point: N/A

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine1-Methylethylester

(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate is an alanine derivative[1].

  • CAS Number: 1334513-02-8
  • MF: C18H17F5NO5P
  • MW: 453.297
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 442.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.5±31.5 °C

1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 5306-85-4
  • MF: C8H14O4
  • MW: 174.19
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 236.4±40.0 °C at 760 mmHg
  • Melting Point: -70°C
  • Flash Point: 108.3±0.0 °C

3-azidotyrosine

H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1].

  • CAS Number: 129960-90-3
  • MF: C9H10N4O3
  • MW: 222.20100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Decyl-N,N-dimethyldecan-1-aminium bromide

Didecyldimethylammonium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 2390-68-3
  • MF: C22H48BrN
  • MW: 406.527
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 149-151 °C(lit.)
  • Flash Point: N/A

Ginsenoside Rk2

Ginsenoside Rk2 is a dammarane glycoside isolated from the processed ginseng (SG; Sun Ginseng)[1].

  • CAS Number: 364779-14-6
  • MF: C36H60O7
  • MW: 604.857
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 693.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 373.5±31.5 °C

5-(Trifluoromethyl)cytidine

5-(Trifluoromethyl)cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 76514-02-8
  • MF: C10H12F3N3O5
  • MW: 311.21
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium diatrizoate

Sodium diatrizoate is an iodinated radiocontrast agent.

  • CAS Number: 737-31-5
  • MF: C11H8I3N2NaO4
  • MW: 635.895
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 614.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 325.2ºC

1,2-Propylene-d6 carbonate

1,2-Propylene-d6 carbonate is the deuterium labeled 1,2-Propylene carbonate[1].

  • CAS Number: 202480-74-8
  • MF: C4D6O3
  • MW: 108.12600
  • Catalog: Others
  • Density: 1.239 g/cm3
  • Boiling Point: 241.699ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 135.257ºC

AA-14

AA-14 is an orphan G protein-coupled receptor GPR101 agonist that partially restores the function of the GH/IGF-1 axis[1].

  • CAS Number: 723740-38-3
  • MF: C14H12F3N3S
  • MW: 311.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cy3-PEG2-endo-BCN

Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

  • CAS Number: 1663449-60-2
  • MF: C47H63ClN4O5
  • MW: 799.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

sodium borodeuteride

Sodium borodeuteride-d4 is the deuterium labeled Sodium borodeuteride[1].

  • CAS Number: 15681-89-7
  • MF: BD4Na
  • MW: 41.85720
  • Catalog: Others
  • Density: 1.07
  • Boiling Point: N/A
  • Melting Point: 300ºC
  • Flash Point: N/A

BDY FL-X,SE

BODIPY FL-X,SE is a fluorescent green dye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λabs: 504 nm; λem:510 nm[1].

  • CAS Number: 217190-09-5
  • MF: C24H29BF2N4O5
  • MW: 502.31900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Obeticholic acid

INT-747 is a potent and selective farnesoid X receptor (FXR) agonist with an EC50 of 99 nM.

  • CAS Number: 459789-99-2
  • MF: C26H44O4
  • MW: 420.625
  • Catalog: FXR
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 562.9±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 308.3±19.7 °C

Glucosinalbate

Glucosinalbate is a natural product isolated from Arabidopsis thaliana[1].

  • CAS Number: 19253-84-0
  • MF: C15H21NO9S2
  • MW: 425.43100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Leu-Gly-OH

H-D-Leu-Gly-OH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 997-05-7
  • MF: C8H16N2O3
  • MW: 188.22400
  • Catalog: Others
  • Density: 1.136g/cm3
  • Boiling Point: 410.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 202ºC

TSQ

TSQ is a fluorescent sensor for cellular zinc, can image zinc proteins (λmax ~470 nm)[1].

  • CAS Number: 109628-27-5
  • MF: C17H16N2O3S
  • MW: 328.38600
  • Catalog: Others
  • Density: 1.334g/cm3
  • Boiling Point: 518.8ºC at 760mmHg
  • Melting Point: 133–134 °C (lit.)
  • Flash Point: 267.5 °C - closed cup (lit.)