Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1-Bromotetradecane-d4

1-Bromotetradecane-d4 is the deuterium labeled 1-Bromotetradecane[1].

  • CAS Number: 1219798-81-8
  • MF: C14H29Br
  • MW: 277.284
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 307.5±5.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 127.3±10.5 °C
  • CAS Number: 32769-02-1
  • MF: C23H22O13
  • MW: 506.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Primulic acid I

Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid)[1].

  • CAS Number: 65312-86-9
  • MF: C54H88O23
  • MW: 1105.26
  • Catalog: Others
  • Density: 1.48±0.1 g/cm3 (20 ºC 760 Torr)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ethyl ethoxalylpropionate

Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release[1].

  • CAS Number: 759-65-9
  • MF: C9H14O5
  • MW: 202.204
  • Catalog: Opioid Receptor
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 249.9±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 111.3±22.7 °C

Ethyl 3-methylpentanoate

Ethyl 3-methylpentanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 5870-68-8
  • MF: C8H16O2
  • MW: 144.21100
  • Catalog: Others
  • Density: 0.87
  • Boiling Point: 158-159°C
  • Melting Point: N/A
  • Flash Point: 75°C/50mm

Sodium edetate

Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can also decrease the formation of disulfide bonds[1][2][3].

  • CAS Number: 64-02-8
  • MF: C10H12N2Na4O8
  • MW: 380.17
  • Catalog: Others
  • Density: 6.9 g/cm3
  • Boiling Point: 614.2ºC at 760 mmHg
  • Melting Point: >300 °C(lit.)
  • Flash Point: 325.2ºC

Jasmonic acid

Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of α-Linolenic acid (HY-N0728). Jasmonic acid signaling can also induce the MAP kinase cascade pathway, calcium channel, and many processes that interact with signaling molecules[1][2].

  • CAS Number: 6894-38-8
  • MF: C12H18O3
  • MW: 210.27000
  • Catalog: Others
  • Density: 1.061g/cm3
  • Boiling Point: 358.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 184.6ºC

α-Methyl-DL-methionine

α-Methyl-DL-methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 2749-07-7
  • MF: C6H13NO2S
  • MW: 163.23800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-Lactose monohydrate

α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes[1][2][3].

  • CAS Number: 5989-81-1
  • MF: C12H24O12
  • MW: 360.31
  • Catalog: Others
  • Density: 1.53 g/cm3
  • Boiling Point: 667.9ºC at 760 mmHg
  • Melting Point: 219ºC
  • Flash Point: 357.8ºC

Monofucosyllacto-N-hexaose I

Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide[1].

  • CAS Number: 341511-38-4
  • MF: C46H78N2O35
  • MW: 1219.10
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Dap(Fmoc)-OH

(S)-2,3-Bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid is an alanine derivative[1].

  • CAS Number: 201473-90-7
  • MF: C33H28N2O6
  • MW: 548.585
  • Catalog: Others
  • Density: 1.330
  • Boiling Point: 809.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 443.4±34.3 °C

Domiphen bromide

Domiphen bromide is a chemical antiseptic and a quaternary ammonium compound, used as a cationic surfactant.

  • CAS Number: 538-71-6
  • MF: C22H40BrNO
  • MW: 414.463
  • Catalog: Potassium Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 117-119 °C(lit.)
  • Flash Point: N/A

Fmoc-L-Lys(4-N3-Z)-OH

Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2].

  • CAS Number: 1446511-14-3
  • MF: C29H29N5O6
  • MW: 543.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S,S)-GNE 5729

(S,S)-GNE 5729 is a (S,S)-enantiomer of GNE 5729 (HY-107409)[1].

  • CAS Number: 2026636-06-4
  • MF: C17H10Cl2F3N5O
  • MW: 428.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Uniblue A sodium salt

Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM)[1].

  • CAS Number: 14541-90-3
  • MF: C22H15N2NaO7S2
  • MW: 506.48300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC(lit.)
  • Flash Point: N/A

Tyrosine Protein Kinase JAK 2 Phospho-Tyr8, 9

Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2.

  • CAS Number: 247171-44-4
  • MF: C88H138N20O34P2
  • MW: 2082.1
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Benzoylhistidine

Benzoyl-L-histidine Monohydrate is a histidine derivative[1].

  • CAS Number: 5354-94-9
  • MF: C13H13N3O3
  • MW: 259.261
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 662.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 354.3±30.1 °C

GNE-064

GNE-064 (compound 5) is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of drug synthesis[1].

  • CAS Number: 1997321-20-6
  • MF: C17H21N5O2
  • MW: 327.38
  • Catalog: Epigenetic Reader Domain
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DL-Ala-Gly-OMe

Methyl alanylglycinate is an amino acid derivative can synthesize peptides[1].

  • CAS Number: 438002-26-7
  • MF: C6H12N2O3
  • MW: 160.17100
  • Catalog: Others
  • Density: 1.135
  • Boiling Point: 296℃
  • Melting Point: 101-102℃
  • Flash Point: 133℃

2,4-DIFLUORORESORCINOL

2,4-Difluororesorcinol is a fluorinated building block[1].

  • CAS Number: 195136-71-1
  • MF: C6H4F2O2
  • MW: 146.09200
  • Catalog: Others
  • Density: 1.542±0.06 g/cm3(Predicted)
  • Boiling Point: 211.3±35.0 °C(Predicted)
  • Melting Point: 57-88ºC
  • Flash Point: N/A

Senkyunolide G

Senkyunolide G (3-Hydroxysenkyunolide A) is a natural product that can be isolated from Angelica sinensis[1].

  • CAS Number: 94530-85-5
  • MF: C12H16O3
  • MW: 208.254
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 424.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.0±20.1 °C

(D)-(-)-α-4-hydroxyphenyl glycine

D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190)[1].

  • CAS Number: 22818-40-2
  • MF: C8H9NO3
  • MW: 167.162
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 365.8±32.0 °C at 760 mmHg
  • Melting Point: 240 °C (dec.)(lit.)
  • Flash Point: 175.0±25.1 °C

Boc-O-tert-butyl-L-threonine

Boc-Thr(tBu)-OH is a threonine derivative[1].

  • CAS Number: 13734-40-2
  • MF: C13H25NO5
  • MW: 275.341
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 391.3±37.0 °C at 760 mmHg
  • Melting Point: 95-98ºC
  • Flash Point: 190.4±26.5 °C

11C-MK-3168

11C-MK-3168 is a potent, reversible and blood/brain barrier penetrated fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 1.0, 1.7 and 5.5 nM for human, rat and rhesus FAAH, respectively.

  • CAS Number: 1242441-58-2
  • MF: C2011CH21ClN4OS
  • MW: 411.94
  • Catalog: FAAH
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-(6)-Carboxy RhodFluor

Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement of intracellular pH[1].

  • CAS Number: 126208-12-6
  • MF: C27H19NO6
  • MW: 453.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-L-Lys(Nvoc)-OH

Fmoc-L-Lys(Nvoc)-OH is a lysine derivative[1].

  • Density: 1.326±0.06 g/cm3(Predicted)
  • Boiling Point: 848.4±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

BaccatinIV

Baccatin IV is a taxane diterpenoid. Baccatin IV can be isolated and identified from the root bark of Taxus mairei[1].

  • CAS Number: 57672-77-2
  • MF: C32H44O14
  • MW: 652.683
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 649.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.6±25.0 °C

L-Methionine-1-13C

L-Methionine-1-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

  • CAS Number: 81202-04-2
  • MF: C413CH11NO2S
  • MW: 150.204
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 273ºC (dec.)(lit.)
  • Flash Point: N/A

Fmoc-Val-OPfp

Fmoc-Val-Opfp is a valine derivative[1].

  • CAS Number: 86060-87-9
  • MF: C26H20F5NO4
  • MW: 505.43300
  • Catalog: Others
  • Density: 1.373g/cm3
  • Boiling Point: 587.1ºC at 760 mmHg
  • Melting Point: 121-122 °C
  • Flash Point: 308.8ºC

chlorantraniliprole

Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).

  • CAS Number: 500008-45-7
  • MF: C18H14BrCl2N5O2
  • MW: 483.146
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 526.6±50.0 °C at 760 mmHg
  • Melting Point: 208 - 210 °C
  • Flash Point: 272.3±30.1 °C