Angelol M,isolated from the roots of Angelica gigas Nakai, shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells[1].
Tryptophyltryptophan (NSC 524592) is a biologically active peptide.
(E)-4-(3,4-Dimethoxyphenyl)but-3-ene-1,2-diol is a phenylbutanoid compound[1].
(R)-2-Amino-4-methylpentanamide hydrochloride is a leucine derivative[1].
Demethylvestitol is a isoflavan compound that can be found in Baoyuan Decoction, a traditional Chinese medicine formula[1].
DPPC-d66 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
α-Methyl-DL-phenylalanine is a phenylalanine derivative[1].
TAPSO sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Spacer phosphoramidite C3 is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
CFSE is a fluorescent dye which can track the cell division.
DL-O-Tyrosine is a tyrosine derivative[1].
Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM[1].
Fmoc-L-Lys(Dde)-OH is a lysine derivative[1].
3-epi-Digitoxigenin is a triterpene isolated from the leaves and stems of Plumeria frangipani.
Perylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Ethyl (tert-Butoxycarbonyl)glycinate is a Glycine (HY-Y0966) derivative[1].
5-Hydroxy-7-acetoxy-8-methoxyflavone (compound F24) is a flavone[1].
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds[1].
H-His(Trt)-OH is a histidine derivative[1].
DHOG is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial therapy for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1].
p-Toluenesulfonic acid monohydrate, a strong organic acid, acts as organic catalyst used in organic synthesis [1][2].
Cholesteryl (pyren-1-yl)hexanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Phenyl α-D-Glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Noxa A BH3 is a biological active peptide. (BH3 domain of Noxa protein)
Piperidin-4-amine-d5 is the deuterium labeled Piperidin-4-amine[1].
(S)-NADH-d1 is the deuterium labeled (S)-NADH. NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle[1][2].
Gomisin O is isolated from the fruits of Schizandra chinensis[1].