Ethyl 3-oxoheptanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
3-Methyl-2-oxobutanoic acid-13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC)[1].
1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent[1].
KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].
rac-1,2-Distearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Erysotramidine is an alkaloid that can be isolated from the stem barks of Erythrina stricta[1].
2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
2-Ethyl-6-methylaniline-d13 is the deuterium labeled 2-Ethyl-6-methylaniline[1].
Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.Target: OthersBuflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. In the EU, buflomedil, a vasoactive agent, was indicated for treatment of PAOD symptoms, specifically in patients with stage II PAOD who experience severe pain when walking even relatively short distances. Buflomedil is not currently approved by the US Food and Drug Administration for use in the United States.
pTH (1-84) (dog) is a biologically active peptide.
Etioporphyrin I is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
BCECF is a duorescent dye with λexcitation of 420~520 nm and λemission of 530 nm.
Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Solvent Yellow 93 is an azomethine dye. Solvent Yellow 93 is used as a colorant of toner[1][2].
5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Methyl octanoate, a volatile compound, is an aroma component persimmon wine[1].
2-Amino-2-(4-(trifluoromethoxy)phenyl)acetic acid is a Glycine (HY-Y0966) derivative[1].
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.IC50 value: 200-1000 nM(EC50) [1]Target: PAR2 agonistNeither AC-55541 nor AC-264613 had activity at any of the other PAR receptor subtypes, nor did they have any significant affinity for over 30 other molecular targets involved in nociception. Visualization of EYFP-tagged PAR2 receptors showed that each compound stimulated internalization of PAR2 receptors. AC-55541 was well absorbed when administered intraperitoneally to rats, reaching micromolar peak plasma concentrations. AC-55541 was stable to metabolism by liver microsomes and maintained sustained exposure in rats, with elimination half-lives of 6.1 h. Intrapaw administration of AC-55541 or AC-264613 elicited robust and persistent thermal hyperalgesia and edema. Coadministration of either a tachykinin 1 (neurokinin 1) receptor antagonist or a transient receptor potential vanilloid (TRPV) 1 antagonist completely blocked these effects. Systemic administration of either AC-55541 or AC-264613 produced a similar degree of hyperalgesia as was observed when the compounds were administered locally.
(Rac)-H-Thr-OMe hydrochloride is the inactive isomer of H-Thr-OMe hydrochloride (HY-W008086), and can be used as an experimental control. H-Thr-OMe.HCl is a threonine derivative[1].
5-Methylpyridin-2(1H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Steviol is a major metabolite of the sweetening compound stevioside. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation[1].
Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops[1].
4-Nitrophenyl α-L-arabinofuranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Boc-L-Ala-OH-2-13C is a 13C-labeled H-Lys-OH.2HCl[1].
n-Undecyl β-D-maltopyranoside is a malted glycoside.
Mangafodipir is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver.
MMT-Hexylaminolinker Phosphoramidite is a cleavable linker. MMT-Hexylaminolinker Phosphoramidite can be used to syntheses oligonucleotide gapmers or other nucleic acid molecules[1][2].
Hydrophobic inducer of the degradation of stabilized proteins, degrading HaloTag2 fusion proteins
1'-Hydroxymidazolam-13C3 is the 13C labeled 1'-Hydroxymidazolam[1].