HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid. Ex: 490 nm; Em 527 nm[1].
N-(2-Hydroxyethyl)-2-phenylacetamide is a fluorescent dye[1].
Taxiphyllin (Compound 3) is a compound isolated from ethanol extract of the aerial parts of Hydrangea macrophylla[1].
5-Hydroxyseselin is a natural product isolated from Metrodorea flavida[1].
RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity[1].
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant[1][2][3].
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[1][4].
Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase[1].
Mono(3-carboxypropyl) phthalate-d4 (MCPP-d4) is a deuterium labeled Mono(3-carboxypropyl) phthalate (HY-133673). Mono(3-carboxypropyl) phthalate (MCPP) is a metabolite of Di-n-octyl phthalate. Di-n-octyl phthalate (DnOP) is a plasticizer used in polyvinyl chloride plastics, cellulose esters, and polystyrene resins[1][2].
(tert-Butoxycarbonyl)-D-histidine is a histidine derivative[1].
2,2′,3,4,5,5′-Hexachlorobiphenyl-3′,4′,6′-d3 is the deuterium labeled 2,2′,3,4,5,5′-Hexachlorobiphenyl[1].
N,N-dimethyl-4-(phenyldiazenyl)aniline-d5 is the deuterium labeled N,N-dimethyl-4-(phenyldiazenyl)aniline[1].
L-Fucitol (1-Deoxy-D-galactitol) is a sugar alcohol isolated from Nutmeg[1].
cis-2-Penten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.
4-Feruloylquinic acid may be a potential biomarker for food products[1].
Dehydronitrosonisoldipine is a calcium channel antagonist.
GLPG0492 is a novel selective androgen receptor modulator; exhibited anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate after oral dosing.IC50 value:Target: AR modulatorGLPG0492 has very good pharmacokinetic properties, including bioavailability in rat (F > 50%), and is currently under evaluation in phase I clinical trials [1]. GLPG0492 is a new non-steroidal selective androgen receptor modulator that is currently under development for musculo-skeletal diseases such as sarcopenia and cachexia. In acute exhaustion tests, a surrogate of the 6-min walking test used in DMD patients, GLPG0492 preserved running performance, whereas vehicle- or comparator-treated animals showed a significant increase in fatigue (30-50%) [2]. GLPG0492 treatment partially prevents immobilization-induced muscle atrophy with a trend to promote muscle fiber hypertrophy in a dose-dependent manner. Interestingly, GLPG0492 was found as efficacious as TP at reducing muscle loss while sparing reproductive tissues. Furthermore, gene expression studies performed on tibialis samples revealed that both GLPG0492 and TP were slowing down muscle loss by negatively interfering with major signaling pathways controlling muscle mass homeostasis [3].
(R)-2-formamido-4-methylpentanoic acid is a leucine derivative[1].
2"-O-Galloylquercitrin (Compound 6) is isolated from the natural Acer ginnala. 2"-O-Galloylquercitrinhas health benefits. 2"-O-Galloylquercitrin has the activity of free radical scavenger [1].
Efmitermant alfa (ACE-083) is a locally acting, follistatin-based fusion protein. Efmitermant alfa also is a muscle-promoting agent. Efmitermant alfa can be used for the research of muscle disorders[1][2].
3,4-Dihydro Naratriptan is a serotonin 5-HT1-receptor agonist. 3,4-Dihydro Naratriptan exhibits selective vasoconstrictor activity. 3,4-Dihydro Naratriptan can be used for migraine diseases research[1].
Methyl 2-amino-2-cyclopropylacetate hydrochloride is a Glycine (HY-Y0966) derivative[1].
Echinatine N-oxide is a pyrrolizidine alkaloid found in R. graeca[1].
1,4,7-Triazonane (1,4,7-Triazacyclononane), an intermediate in the synthesis of 1,4,7-trifunctionalized derivatives, is a possible reagent for compleximetric titrations with high cation-binding selectivity[1][2].
2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene (compound 4) is a neolignan, which can be isolated from the aerial parts of Rodgersia podophylla[1].
Dihydromollugin is a natural naphthoic acid ester[1].
Elucaine is a muscarinic acetylcholine receptor antagonist with anti-ulcerative activity.
D-Mannose isomerase is a carbohydrate isomerase catalyzing the reversible isomerization of d-mannose to d-fructose. D-Mannose isomerase belongs to the N-acylglucosamine 2-epimerase (AGE) superfamily along with AGE, cellobiose 2-epimerase (CE), and aldose-ketose isomerase (AKI)[1].