Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

CB1R Allosteric modulator 1

CB1R Allosteric modulator 1 (compound 11) is a potent CB1R allosteric modulator. CB1R Allosteric modulator 1 shows negatively affects the functional activity of orthosteric ligands (NAM) at CB1Rs[1].

  • CAS Number: 2513102-41-3
  • MF: C24H24ClN3O
  • MW: 405.92
  • Catalog: Cannabinoid Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tryptamine-d4 Hydrochloride

Tryptamine-d4 hydrochloride is the deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride, a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter[1].

  • CAS Number: 340257-60-5
  • MF: C10H9D4ClN2
  • MW: 200.70100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Niraparib metabolite M1

Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

  • CAS Number: 1476777-06-6
  • MF: C19H19N3O2
  • MW: 321.373
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 442.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.1±28.7 °C

(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11)

[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) also increases motor activity and induces recovery of cocaine-seeking behavior in rats[1][2][3].

  • CAS Number: 77128-69-9
  • MF: C43H61N9O9S
  • MW: 880.064
  • Catalog: Neurokinin Receptor
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1291.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 734.7±34.3 °C

Hydroxy Bezafibrate-d6

Hydroxy Bezafibrate-d6 is the deuterium labeled Hydroxy Bezafibrate[1].

  • CAS Number: 2673270-01-2
  • MF: C19H14D6ClNO5
  • MW: 383.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sephadex G 200

Sephadex G 200 is a hydrophilic gel that can be used as a gel filter filler (Particle size range: 40-120 μm; Sphere protein separation range: 5k-600k Da)[1].

  • CAS Number: 9041-36-5
  • MF: C120H98Cl2F6N16O19
  • MW: 2253.0
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CPP2

CPP2 is a cell-penetrating peptide, with a high intracellular translocation efficiency[1].

  • CAS Number: 1313390-49-6
  • MF: C97H135N23O24
  • MW: 2007.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-AMINO-3-ETHYL-PENTANOIC ACID

3-Ethylnorvaline (3-Ethyl-DL-norvaline) is a derivative of Norvaline, can be used to the synthesis of drugs or other compounds[1].

  • CAS Number: 14328-54-2
  • MF: C7H15NO2
  • MW: 145.19900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Levulinic acid

Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate.

  • CAS Number: 123-76-2
  • MF: C5H8O3
  • MW: 116.115
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 242.9±13.0 °C at 760 mmHg
  • Melting Point: 30-33 °C(lit.)
  • Flash Point: 137.8±0.0 °C

Fiduxosin

Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.

  • CAS Number: 208993-54-8
  • MF: C30H29N5O4S
  • MW: 555.64700
  • Catalog: Adrenergic Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY FL azide

BDP FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments[1].

  • CAS Number: 1379771-95-5
  • MF: C17H21BF2N6O
  • MW: 374.196
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

p-Dimethylaminobenzaldehyde

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].

  • CAS Number: 100-10-7
  • MF: C9H11NO
  • MW: 149.190
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 176-177 ºC (17 mmHg)
  • Melting Point: 72-75 °C(lit.)
  • Flash Point: 164 ºC

6-ROX hydrochloride

6-ROX (6-Carboxy-X-rhodamine) hydrochloride, a fluorescent marker of oligonucleotides, acts as a receptor coupled to 5-FAM and as a donor in FRET imaging. Excitation wavelength: 568 nm. Emission wavelength: 568 nm.

  • CAS Number: 1689512-96-6
  • MF: C33H31ClN2O5
  • MW: 571.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Dimethyl-2,3-diphenylbutane

2,3-Dimethyl-2,3-diphenylbutane is one of the decomposition of Dicumylperoxide (DCP). Diallyl orthophthalate (DAOP) is a reactive plasticizer initiated by 2,3-dimethyl-2,3-diphenylbutane for improving polyphenylene oxide (PPO) processing[1][2].

  • CAS Number: 1889-67-4
  • MF: C18H22
  • MW: 238.36700
  • Catalog: Others
  • Density: 0.95 g/cm3
  • Boiling Point: 306.1ºC at 760 mmHg
  • Melting Point: 90-110 °C
  • Flash Point: 142.7ºC

Shield-1

Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein[1][2].

  • CAS Number: 914805-33-7
  • MF: C42H56N2O10
  • MW: 748.90
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

15:0 SM (d18:1/15:0)-d9

15:0 SM (d18:1/15:0)-d9 is deuterium labeled 15:0 SM (d18:1/15:0).

  • CAS Number: 2315262-22-5
  • MF: C38H68D9N2O6P
  • MW: 698.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Delphinidin 3-diglucoside

Delphinidin 3-diglucoside (Delphinidol 3-sophoroside) is a phenolic compound that can be isolated from Punica granatum[1].

  • CAS Number: 59212-40-7
  • MF: C27H31ClO17
  • MW: 662.98
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[[[[(2S,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxola n-2-yl]amino]oxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid

5-Azacytidine 5′-triphosphate (5-aza-CMP) is a cytidine analog that inhibitss the incorporation of [3H]CTP, but not [3H]UTP, into RNA in the DNA-dependent RNA polymerase reaction[1].

  • CAS Number: 2226-74-6
  • MF: C8H15N4O14P3
  • MW: 484.14
  • Catalog: Others
  • Density: 2.66g/cm3
  • Boiling Point: 860.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 474.4ºC

quizalofop-ethyl

Quizalofop-ethyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 76578-14-8
  • MF: C19H17ClN2O4
  • MW: 372.80200
  • Catalog: Others
  • Density: 1.301 g/cm3
  • Boiling Point: 503.9ºC at 760 mmHg
  • Melting Point: 91.7-92.1ºC
  • Flash Point: 100ºC

1-(2H3)Methyl-1H-pyrrole

N-Methyl pyrrole-d3 is the deuterium labeled N-Methyl pyrrole[1].

  • CAS Number: 20687-13-2
  • MF: C5H4D3N
  • MW: 84.134
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 112.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 15.0±0.0 °C

D-Asparagine hydrate

(R)-2,4-diamino-4-oxobutanoic acid hydrate is an asparagine derivative[1].

  • CAS Number: 5794-24-1
  • MF: C4H10N2O4
  • MW: 150.133
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 408.5ºC at 760 mmHg
  • Melting Point: 275 °C (dec.)(lit.)
  • Flash Point: 200.9ºC

WAY-313318

WAY-313318 is an active molecule.

  • CAS Number: 351993-88-9
  • MF: C13H10Cl2N4
  • MW: 293.15
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 512.5±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 263.8±27.3 °C

Fmoc-N-Me-Val-OH

Fmoc-N-Me-Val-OH is a modified peptide.

  • CAS Number: 84000-11-3
  • MF: C21H23NO4
  • MW: 353.412
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 527.6±29.0 °C at 760 mmHg
  • Melting Point: 187-190ºC
  • Flash Point: 272.9±24.3 °C

Neurogranin Fragment 28-43

Neurogranin 28-43 is a biological active peptide. (selective PKC substrate)

  • CAS Number: 146554-17-8
  • MF: C78H134N28O19S
  • MW: 1800.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3,5,6-Tetrachloro-1,1'-biphenyl-d5

2,3,5,6-Tetrachloro-1,1'-biphenyl-d5 is the deuterium labeled 2,3,5,6-Tetrachloro-1,1'-biphenyl[1].

  • CAS Number: 1219794-80-5
  • MF: C12HD5Cl4
  • MW: 297.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Carbodenafil

Carbodenafil is a Sildenafil (UK-92480) related compound found in health foods. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM[1].

  • CAS Number: 944241-52-5
  • MF: C24H32N6O3
  • MW: 452.54900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Screen

Pyridate (CL 11344) is a herbicide, which is used in the agricultural management of cereals, maize and rape[1].

  • CAS Number: 55512-33-9
  • MF: C19H23ClN2O2S
  • MW: 378.92
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 544.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 283.3±32.9 °C

Methoxymethyl Trimethylsilane

Methoxymethyltrimethylsilane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 14704-14-4
  • MF: C5H14OSi
  • MW: 118.250
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 83.9±0.0 °C at 760 mmHg
  • Melting Point: <0ºC
  • Flash Point: -13.3±0.0 °C

5-FAM maleimide

5-FAM maleimide is a 5-FAM (HY-66022) derivative. 5-FAM maleimide can be used to label proteins[1].

  • CAS Number: 787632-00-2
  • MF: C27H18N2O8
  • MW: 498.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,5,5-TRIFLUORO-DL-LEUCINE

5,5,5-Trifluoro-DL-leucine is a leucine derivative[1].

  • CAS Number: 2792-72-5
  • MF: C6H10F3NO2
  • MW: 185.14400
  • Catalog: Others
  • Density: 1.294g/cm3
  • Boiling Point: 217.4ºC at 760 mmHg
  • Melting Point: 273ºC
  • Flash Point: 85.3ºC