Bz-rA Phosphoramidite is used for ribonucleotides modification[1].
Boc-His-OMe is a histidine derivative[1].
Alnusenone (Glutinone) is a stabilised intermediate int he biogenesis of friedelin (XV) from squalene. Alnusenone is the major natural compound in fractions[1].
ARC7 can act as a probe for secondary metabolism in S. coelicolor. ARC7 is a tool for studying secondary metabolism and the streptomycete life cycle[1].
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
1-Heptacosanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Gly-Phe-AFC is a fluorescent substrate, which is a peptide sequence composed of glycine and phenylalanine, linked to the fluorescent group AFC[1].
Z-Ser-OH is a serine derivative[1].
2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives[1][2].
Oxazine 170 perchlorate is a laser dye with a wide excitation spectrum range (300−550 nm), which strongly absorbs light with a wavelength greater than 550 nm, and it emits fluorescence with a wavelength of about 645 nm[1].
Rhyncholphylline, an alkaloid isolated from Uncaria, shows potent inhibition of lipopolysaccharide (LPS)-induced NO production in rat primary microglial cells.IC50 value:Target:In vitro: Rhyncholphylline effectively suppresses release of proinflammatory cytokines in LPS-activated microglial cells and the underling molecular mechanism for the inhibition of microglial activation; Attenuated LPS-induced production of proinflammatory cytokines such as TNF-α and IL-1β as well as NO in mouse N9 microglial cells [1]. Rhynchophylline exerts it protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia [3].In vivo: The neuroprotective effect of rhynchophylline was investigated in a stroke model. Following pMCAO, rhynchophylline treatment not only ameliorated neurological deficits, infarct volume and brain edema, but also increased claudin-5 and BDNF expressions (p < 0.05). Moreover, rhynchophylline could activate PI3K/Akt/mTOR signaling while inhibiting TLRs/NF-κB pathway [2].
Nα,Nα-Bis(carboxymethyl)-L-lysine hydrate is a lysine derivative[1].
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
4-Bromobenzonitrile-d4 is the deuterium labeled 4-Bromobenzonitrile[1].
1,2-Bis(4-(benzo[d]oxazol-2-yl)phenyl)ethene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung[1][2].
Imidazoleacetic acid is an endogenous ligand that stimulates imidazole receptors.
Ethyl 10-Undecenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Mono-6-O-mesitylenesulfonyl-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery[1][2].
N-Dodecyl-N,N-dimethyldodecan-1-aminium-d5 (bromide) is the deuterium labeled N-Dodecyl-N,N-dimethyldodecan-1-aminium bromide[1].
Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].
(S)-3-((tert-Butoxycarbonyl)amino)-3-(pyridin-3-yl)propanoic acid is an alanine derivative[1].
G0 N-glycan-Asn is a glycopeptide. G0 N-glycan-Asn can be used for various biochemical studies[1].
(4S)-4-Phenyl-L-proline is a proline derivative[1].
N-Benzoyl-DL-arginine-4-nitroanilide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Azobenzene can be used as an optical trigger for the design and synthesis of a large variety of photoresponsive systems.
Estrone 3-glucuronide, the dominant metabolite of estradiol, is determined to be the urinary marker for prediction of the fertile window[1].
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation.