Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

11-Hydroxyrankinidine

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans[1].

  • CAS Number: 122590-03-8
  • MF: C20H24N2O4
  • MW: 356.42
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 550.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.9±32.9 °C

Hexamethylphosphoramide-d18

Hexamethylphosphoramide-d18 is the deuterium labeled Hexamethylphosphoramide[1].

  • CAS Number: 51219-90-0
  • MF: C6H18N3OP
  • MW: 179.20000
  • Catalog: Others
  • Density: 1.032g/cm3
  • Boiling Point: 233ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 94.7ºC

Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH

Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 908601-15-0
  • MF: C37H39N3O8
  • MW: 653.72100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-(4-(Sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid

Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

  • CAS Number: 1335202-59-9
  • MF: C16H16N2O3S
  • MW: 316.37
  • Catalog: Others
  • Density: 1.31±0.1 g/cm3 (20 ºC 760 Torr)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 5-hydroxypyridine-2-carboxylate

Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro[1].

  • CAS Number: 30766-12-2
  • MF: C7H7NO3
  • MW: 153.135
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 374.2±22.0 °C at 760 mmHg
  • Melting Point: 193.5-195.5℃
  • Flash Point: 180.1±22.3 °C

Bkm1644

BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.

  • CAS Number: 1070966-96-9
  • MF: C34H37Cl2F5N2O9P2
  • MW: 845.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoxanthohumol

(2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol[1].

  • CAS Number: 70872-29-6
  • MF: C21H22O5
  • MW: 354.396
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 585.8±50.0 °C at 760 mmHg
  • Melting Point: 196-208℃
  • Flash Point: 208.6±23.6 °C

Justin C

Justin C (compound 14) is a nature product that could be isolated from Justicia procumbens. Justin C can be used in research of cancer[1].

  • CAS Number: 202655-28-5
  • MF: C26H34O9
  • MW: 490.54
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Monensin methyl ester

Monensin methyl ester, a neutral analog of monensin, is an ion active component for Na+ selective disk electrodes[1].

  • CAS Number: 28636-21-7
  • MF: C37H64O11
  • MW: 684.89700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BMP2-derived peptide

BMP2-derived peptide is a functional motif from positions 73 to 92 of the amino acid sequence of BMP-2. BMP2-derived peptide promotes osteogenic differentiation of bone marrow stromal cells (BMSCs) and enhances bone regeneration[1].

  • CAS Number: 836606-84-9
  • MF: C104H176N26O32S
  • MW: 2334.73
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY 505/515

BODIPY 505/515, a lipophilic bright green fluorescent dye was tested for lipid detection in the microalga Tetraselmis subcordiformis. BODIPY 505/515 displays excitation/emission maxima of 505/515 nm, respectively, and has been used for live and fixed cell applications[1].

  • CAS Number: 21658-70-8
  • MF: C13H15BF2N2
  • MW: 248.08
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Suc-Ala-Phe-Lys-AMC

Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K[1][2].

  • CAS Number: 73207-91-7
  • MF: C32H39N5O8
  • MW: 621.68100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RdRP-IN-3

RdRP-IN-3 is a promising anti-influenza drug candidate by inhibiting the activity of RNA-dependent RNA polymerase (RdRp).

  • CAS Number: 2641299-75-2
  • MF: C25H21N3O4
  • MW: 427.45
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

YYRADDA

YYRADDA is a polypeptide. YYRADDA stimulates the growth of collagen in the extracellular matrix of the skin. YYRADDA improves the appearance of the skin and promotes the healing of damaged skin[1].

  • CAS Number: 1082226-36-5
  • MF: C34H47N9O11
  • MW: 757.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4'-O-Glucosylvitexin

Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta[1].

  • CAS Number: 38950-94-6
  • MF: C27H30O15
  • MW: 594.51800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-L-phenylalanine methyl ester

N-Boc-L-phenylalanine methyl ester is a phenylalanine derivative[1].

  • CAS Number: 51987-73-6
  • MF: C15H21NO4
  • MW: 279.332
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 403.8±38.0 °C at 760 mmHg
  • Melting Point: 36-40 °C(lit.)
  • Flash Point: 198.0±26.8 °C

Shz 1

Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

  • CAS Number: 326886-05-9
  • MF: C13H11BrN2O3S
  • MW: 355.207
  • Catalog: Cardiovascular Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 503.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.5±32.9 °C

Coppersensor 1

Coppersensor-1 (CS1) is a boron dipyrromethene (BODIPY)-based fluorescent sensor for selective and sensitive detection of copper(I) ions (Cu+) in biological samples, including live cells[1].

  • CAS Number: 874748-20-6
  • MF: C30H50BF2N3S4
  • MW: 629.81
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DAF-2

4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues[1].

  • CAS Number: 205391-01-1
  • MF: C20H14N2O5
  • MW: 362.336
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 760.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 413.9±32.9 °C

5-Fluorocytidine

5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor[1].

  • CAS Number: 2341-22-2
  • MF: C9H12FN3O5
  • MW: 261.207
  • Catalog: Others
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 511.4±60.0 °C at 760 mmHg
  • Melting Point: 196-200 °C(lit.)
  • Flash Point: 263.1±32.9 °C

17:0-22:4 PE-d5

17:0-22:4 PE-d5 is deuterium labeled 17:0-22:4 PE.

  • CAS Number: 2342575-44-2
  • MF: C44H75D5NO8P
  • MW: 787.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fursultiamine

Fursultiamine is a vitamin B1 derivative.

  • CAS Number: 804-30-8
  • MF: C17H26N4O3S2
  • MW: 398.543
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 652.3±55.0 °C at 760 mmHg
  • Melting Point: 130-136ºC (decompos.)
  • Flash Point: 348.3±31.5 °C

D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine-d7

D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine-d7 is deuterium labeled D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine.

  • CAS Number: 2315262-19-0
  • MF: C37H64D7NO8
  • MW: 665.00
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BR102910

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

  • CAS Number: 2505339-54-6
  • MF: C18H14Cl2F2N4O2S
  • MW: 459.30
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Condurango glycoside E

Condurango glycoside E is a glycoside compound that can be isolated from the bark extract of Marsdenia cundurango[1].

  • CAS Number: 115784-07-1
  • MF: C53H76O18
  • MW: 1001.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tyrosinase-IN-5

Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells[1].

  • CAS Number: 2525175-90-8
  • MF: C18H13N3O6
  • MW: 367.31
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

odoratone

Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm)[1].

  • CAS Number: 16962-90-6
  • MF: C30H48O4
  • MW: 472.700
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 571.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.5±23.6 °C

3-hydroxy-5-methoxy-3-methoxycarbonyl-5-oxo-pentanoic acid

Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

  • CAS Number: 53798-97-3
  • MF: C8H12O7
  • MW: 220.17700
  • Catalog: Others
  • Density: 1.378g/cm3
  • Boiling Point: 405.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 162.6ºC

Glybuzole

Glybuzole (Desaglybuzole) is an orally active hypoglycaemic agent that has antidiabetic effect[1].

  • CAS Number: 1492-02-0
  • MF: C12H15N3O2S2
  • MW: 297.39600
  • Catalog: Metabolic Disease
  • Density: 1.344g/cm3
  • Boiling Point: 449.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 225.6ºC

Medronic Acid

Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging.

  • CAS Number: 1984-15-2
  • MF: CH6O6P2
  • MW: 176.002
  • Catalog: Others
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 583.2±60.0 °C at 760 mmHg
  • Melting Point: 197-199 °C(lit.)
  • Flash Point: 306.5±32.9 °C