Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Polygalaxanthone XI

Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, sedative, and tranquilizing agent[1].

  • CAS Number: 857859-82-6
  • MF: C25H28O15
  • MW: 568.481
  • Catalog: Neurological Disease
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 977.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 329.1±27.8 °C

N-BOC-D-Arginine hydrochloride

(tert-Butoxycarbonyl)-L-arginine hydrochloride is an arginine derivative[1].

  • CAS Number: 35897-34-8
  • MF: C11H23ClN4O4
  • MW: 310.778
  • Catalog: Others
  • Density: 1.28g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: >230 °F

7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-one

Umbelliprenin (compound 2) can be isolated from the chloroform extract of the roots of Heptaptera cilicica[1].

  • CAS Number: 23838-17-7
  • MF: C24H30O3
  • MW: 366.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bakkenolide B

Bakkenolide B is isolated from petasites japonicas leaves and has anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1].

  • CAS Number: 18455-98-6
  • MF: C22H30O6
  • MW: 390.470
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 503.0±50.0 °C at 760 mmHg
  • Melting Point: 101-102 °C
  • Flash Point: 217.1±30.2 °C

TNF-α (31-45), human

TNF-α (31-45), human is a peptide of tumor necrosis factor-α.

  • CAS Number: 144796-71-4
  • MF: C69H122N26O22
  • MW: 1667.87000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CPI-203

(Rac)-CPI-203 is a racemate of CPI-203 (HY-15846) (BET bromodomain inhibitor)[1]

  • CAS Number: 202591-23-9
  • MF: C19H18ClN5OS
  • MW: 399.897
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 690.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 371.4±34.3 °C

Boc-Met-OSu

Boc-Met-OSu is a Methionine (HY-13694) derivative[1].

  • CAS Number: 3845-64-5
  • MF: C14H22N2O6S
  • MW: 346.399
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 120-126ºC
  • Flash Point: N/A

Vitexin2''-O-p-trans-coumarate

Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H2O2[1].

  • CAS Number: 1229437-79-9
  • MF: C30H26O12
  • MW: 578.520
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 884.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 292.8±27.8 °C

Boc-Ala-Ala-pNA

Boc-Ala-Ala-pNA is a serine peptidase[1]

  • CAS Number: 50439-35-5
  • MF: C17H24N4O6
  • MW: 380.39600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gardenoin J

Gardenoin J, a cycloartane triterpene, is isolated from the exudate of Gardenia thailandica.

  • CAS Number: 1345109-46-7
  • MF: C30H48O5
  • MW: 488.69900
  • Catalog: Others
  • Density: 1.14±0.1g/ml
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl behenate

Methyl behenate (Methyl docosanoate) is a naturally fatty acid methyl ester isolated from the plant of Aspidopterys obcordata Lemsl[1].

  • CAS Number: 929-77-1
  • MF: C23H46O2
  • MW: 354.61000
  • Catalog: Others
  • Density: 0.861g/cm3
  • Boiling Point: 393 °C
  • Melting Point: 54-56 °C(lit.)
  • Flash Point: 113 °C

TMR Biocytin

TMR Biocytin is a polar tracer used in the research of cell-cell and cell-liposome fusions, as well as membrane permeability and cellular uptake during pinocytosis. TMR Biocytin can be detected using streptavidin, and is an effective neuronal tracer in live tissue (Ex=544 nm, Em=571 nm)[1].

  • CAS Number: 749247-49-2
  • MF: C46H60N8O7S
  • MW: 869.08
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Siltenzepine

Siltenzepine is an anti-acid agent. It is used in the treatment of peptic ulcers.

  • CAS Number: 98374-54-0
  • MF: C19H20ClN3O4
  • MW: 389.83300
  • Catalog: Others
  • Density: 1.397g/cm3
  • Boiling Point: 618.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.7ºC

Glyceraldehyde phosphate dehydrogenase

Glyceraldehyde phosphate dehydrogenase is the target of anti-thymocyte and anti-apoptotic agents. Glyceraldehyde phosphate dehydrogenase catalyzes the chain oxidation of reduced nicotinamide adenine dinucleotide by perhydroxyl radicals[1][2].

  • CAS Number: 9001-50-7
  • MF: C3H7O6P
  • MW: 170.057841
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,4,5-Trimethoxybenzoic acid-d3

3,4,5-Trimethoxybenzoic acid-d3 is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

  • CAS Number: 84759-05-7
  • MF: C10H3D9O5
  • MW: 221.25500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1].

  • CAS Number: 339-44-6
  • MF: C13H15N3O4S
  • MW: 309.34100
  • Catalog: Metabolic Disease
  • Density: 1.354g/cm3
  • Boiling Point: 515.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 265.4ºC

Oiligodendrocyte differentiation promoter 1

Oiligodendrocyte differentiation promoter 1 belongs to the oiligodendrocyte differentiation promoter.

  • CAS Number: 400760-25-0
  • MF: C25H25Cl2NO5
  • MW: 490.38
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GPR132 antagonist 1

GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 μM[1].

  • CAS Number: 898211-21-7
  • MF: C18H17NO5S
  • MW: 359.40
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(E/Z)-BCI hydrochloride

(E/Z)-BCI hydrochloride is a DUSP6 inhibitor with anti-inflammatory activities. (E/Z)-BCI hydrochloride attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-κB pathway [1].

  • CAS Number: 95130-23-7
  • MF: C22H24ClNO
  • MW: 353.89
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: 484.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 161.3ºC

CIA-1 hcl(452087-38-6 Free base)

CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.

  • CAS Number: 1049691-47-5
  • MF: C17H20ClN3O2S
  • MW: 365.88
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ocean Blue, SE

PB succiniMidyl ester (Ocean Blue, SE) is a blue fluorescent dye, conjugates of this dye are strongly fluorescent even at neutral pH (λExcitation/emission~405/455 nm).

  • CAS Number: 215868-33-0
  • MF: C14H7F2NO7
  • MW: 339.20500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 sodium

1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium).

  • CAS Number: 2342575-50-0
  • MF: C43H73D5NNaO10P
  • MW: 828.07
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4-Fluorophenyl)methanol-d4

(4-Fluorophenyl)methanol-d4 is the deuterium labeled (4-Fluorophenyl)methanol[1].

  • CAS Number: 93111-26-3
  • MF: C7H3D4FO
  • MW: 130.15300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pp60 c-src (521-533) (phosphorylated) trifluoroacetate salt

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527[1].

  • CAS Number: 149299-77-4
  • MF: C62H95N16O28P
  • MW: 1543.48000
  • Catalog: Others
  • Density: 1.461 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RVG-9R trifluoroacetate salt

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction[1][2].

  • CAS Number: 1678417-57-6
  • MF: C201H334N82O55S2
  • MW: 4843.51
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Losmiprofen

Losmiprofen is a nonsteroidal antiinflammatory agent.

  • CAS Number: 74168-08-4
  • MF: C17H15ClO4
  • MW: 318.75200
  • Catalog: Inflammation/Immunology
  • Density: 1.286g/cm3
  • Boiling Point: 469.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.7ºC

6,6'-Di-O-sinapoylsucrose

6,6'-Di-O-sinapoylsucrose is a sucrose ester hat can be found in cynanchum amplexicaule[1].

  • CAS Number: 1068661-35-7
  • MF: C34H42O19
  • MW: 754.69
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FGH10019

FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.

  • CAS Number: 1046045-61-7
  • MF: C18H19N3O2S2
  • MW: 373.492
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 578.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 303.6±32.9 °C

Epimagnolin B

Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

  • CAS Number: 1134188-26-3
  • MF: C23H28O7
  • MW: 416.464
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 548.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 220.9±30.0 °C

TUG-1387

TUG-1387 is a analog of both AH-7614 and TUG-1506 that has no activity at FFA4. TUG-1387 can serve as negative control for studies assessing FFA4 function.

  • CAS Number: 6319-64-8
  • MF: C21H17NO2
  • MW: 315.36500
  • Catalog: Others
  • Density: 1.25g/cm3
  • Boiling Point: 503.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.6ºC