L-Norvaline ethyl ester HCl is a valine derivative[1].
Isomaltotetraose is one of isomalto-oligosaccharide (IMO), the main hydrolysis end products of DexKQ[1]. Isomaltotetraose can induce dextranase synthesis[2].
Baldrinal is derived from the extracts of valerian rhizomes and roots, inhibits autonomic activity, and has anti-inflammatory effects[1].
LH 1 is an immunostimulant used in antitumor treatment.
(Des-Gly2)-Exenatide is a potential impurity of Exenatide (HY-13443).
2,3',4,6-Tetrahydroxybenzophenone, a kind of benzophenone, is the immediate precursor of xanthones in higher plants[1].
Valiolamine, an aminocyclitol has been isolated from the fermentation broth of Streptomyces hygroscopicus subsp. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase[1].
DL-Leucyl-DL-phenylalanine is a dipeptide and can be used as a substrate to detecte two regions of dipeptidase staining on a gel in Drosophila simulans as well as in Drosophila melanogaster[1][2].
HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.
Trombodipine is an antithrombotic agent.
L-Isovaline is a valine derivative[1].
(S)-Boc-3,4-dimethoxy-β-Phe-OH is a phenylalanine derivative[1].
Ipecoside is an alkaloid isolated from Psychotria[1].
KW-6055 is a benzylpyridine derivative and has anti-amnesic activity.
Prexigebersen is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2).
Methyl acetyl-L-cysteinate is a cysteine derivative[1].
Tetrapropylammonium bromide(Reagent for Ion-Pair Chromatography,99%)-15N is the deuterium labeled Tetrapropylammonium bromide(Reagent for Ion-Pair Chromatography,99%)[1].
Blood-group A trisaccharide (A-Trisaccharide) is a oligosaccharide present in the urine of blood group A secretors[1].
1,3-Dioleoylglycerol-d5 is deuterium labeled 1,3-Dioleoylglycerol.
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL4- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice[1].
3,5-Dimethylbenzoic acid-d9 is the deuterium labeled 3,5-Dimethylbenzoic acid[1].
Fissistigine A is an alkaloid separated of the basic fractions from Formosan Fissistigma glaucescens, F. oldhamii and Goniothalamus amuyon[1].
PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine[1].
2-Bromoacetamide can inactivate alcohol dehydrogenase[1].
α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC50 for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity[1].
Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.Target: OthersIdebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects. Idebenone was generally well tolerated with similar numbers of adverse events in each group. One child receiving high-dose idebenone developed neutropenia after 6 months, which resolved after discontinuation of treatment. 8OH2′dG concentrations were not increased, and did not significantly change with idebenone treatment [1]. The 2-year efficacy and safety of idebenone were studied in a prospective, randomized, double-blind multicentre study in 3 parallel groups of patients with dementia of the Alzheimer type (DAT) of mild to moderate degree. A total of 450 patients were randomized to either placebo for 12 months, followed by idebenone 90 mg tid for another 12 months (n = 153) or idebenone 90 mg tid for 24 months (n = 148) or 120 mg tid for 24 months (n = 149). idebenone showed statistically significant dose-dependent improvement in the primary efficacy variable ADAS-Total and in all the secondary efficacy variables [2].
Glomeratide A is a benzophenone C-glucoside with hepatoprotective effects. Glomeratide A has a protective effect against d-galactosamine-induced hepatotoxicity in rat liver epithelial stem-like cells.