BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor (IC50=0.3 nM). BLU2864 shows anti-tumor activity. BLU2864 can be used in cancer and polycystic kidney disease research[1][2].
2,2-Dihydroxy-1-phenylethan-1-one (compound 2d) is an intermediate of pharmaceutical synthesis with antioxidant property[1].
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propanoic acid is a tyrosine derivative[1].
Novel potent inhibitor of the lysophospholipase autotaxin
H-Phg(4-Cl)-OH is a Glycine (HY-Y0966) derivative[1].
Ginsenoside Ra2 is a component from Panax ginseng[1].
6-Maleimidocaproic acid hydrazide (N-ε-maleimidocaproic acid hydrazi) TFA, a Maleimade derivative, is a carbonyl and sulfhydryl reactive heterobifunctional crosslinking reagent[1].
tert-Butyl O-(tert-butyl)-D-threoninate hydrochloride is a threonine derivative[1].
Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch[1].
[Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist.
6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer.
2-Ethoxyphenol-d5 is the deuterium labeled 2-Ethoxyphenol[1].
Neohesperidose is a disaccharide isolated from species of typha[1].
Clerodenoside A is a phenolic glycoside that can be extracted from the stem of Clerodendrum inerme[1].
(Rac)-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (Rac)-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Isoxsuprine-monoester-1, a monoester of isoxsuprine, is a long acting peripheral vasodilator.
UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).
Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 is a L-Lysine (HY-N0469) derivative[1].
Andropanoside is a natural product isolated and purified from the herbs of Andrographis paniculata. Andrographis paniculata possesses a protective activity against various liver disorders[1].
2-Methylanisole-d3 is the deuterium labeled 2-Methylanisole[1]. 2-Methylanisole is a monomethoxybenzene and acts as an intermediate for the preparation of compounds with methylhydroquinone core[2].
Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1].
Metaxalone-d6 is deuterium labeled Metaxalone.
Pep-1 (uncapped) is a cell-penetrating peptide.
7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters[1].
Lemalesomab (IMMU-MN3) is a mouse IgG1 Anti-NCA-90 monoclonal antibody and a Fab'fragment. Lemalesomab can be used for the research of inflammation, infectious lesions and infection imaging[1].
Pseudobufarenogin is a natural compound extracted from toad species with unknown details.
N-(3-Mercapto-2-methylpropanoyl)glycine-d5 is the deuterium labeled N-(3-Mercapto-2-methylpropanoyl)glycine[1].
Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation[1].
Isovalerylshikonin (IVS) is a shikonin pigment is identified in the root epidermis of Echium italicum L[1].
H1PVAT is a potent and selective inhibitor of poliovirus serotypes (PV-1, PV-2, PV-3), and inhibits early stage of the replication. H1PVAT interacts with viral capsid directly and protects PV against heat inactivation[1][2].