Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Trisodium phosphate dodecahydrate

Trisodium phosphate dodecahydrate is a corrosion inhibitor for iron in 0.1 M NaClO4, in both aerated and deaerated solutions. Trisodium phosphate dodecahydrate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 10101-89-0
  • MF: H24Na36O16P
  • MW: 380.18
  • Catalog: Others
  • Density: 1.62
  • Boiling Point: 158ºC at 760 mmHg
  • Melting Point: 75 °C
  • Flash Point: N/A

17:0-14:1 PG-d5

17:0-14:1 PG-d5 is deuterium labeled 17:0-14:1 PG.

  • CAS Number: 2342575-74-8
  • MF: C37H65D5NaO10P
  • MW: 733.94
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hypocrellin C

Hypocrellin C is a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola[1].

  • CAS Number: 149457-83-0
  • MF: C30H26O9
  • MW: 530.52204
  • Catalog: Others
  • Density: 1.52±0.1 g/cm3(Predicted)
  • Boiling Point: 920.2±65.0 °C(Predicted)
  • Melting Point: 232-234℃
  • Flash Point: N/A

Curcumenol

Curcumenol is one of constituents in the plants of medicinally important genus of Curcuma[1].

  • CAS Number: 19431-84-6
  • MF: C15H22O2
  • MW: 234.33
  • Catalog: Cytochrome P450
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 349.3±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 146.7±22.1 °C

GppCp(GMPPCP)

5′-Guanylyl methylenediphosphonate (sodium) is a GTP analogue and a specific, competitive inhibitor of the GTP reaction in protein synthesis[1].

  • CAS Number: 10470-57-2
  • MF: C11H15N5Na3O13P3
  • MW: 587.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

OSBP-IN-1

OSBP-IN-1(compound 12) is a Schweinfurthins analogues targeted of oxysterol-binding protein (OSBP). OSBP-IN-1 has antitumor activity[1].

  • CAS Number: 2890760-43-5
  • MF: C30H36O6
  • MW: 492.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Sar-OH

Z-Sar-OH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 39608-31-6
  • MF: C11H13NO4
  • MW: 223.225
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 385.6±31.0 °C at 760 mmHg
  • Melting Point: 58-59ºC
  • Flash Point: 187.0±24.8 °C

Ivospemin

Ivospemin is an antineoplastic spermine analog[1].

  • CAS Number: 748119-79-1
  • MF: C16H38N4O2
  • MW: 318.50
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Takeda103A

Takeda103A is a potent inhibitor of GRK2. G protein-coupled receptors (GPCRs) are central to many physiological processes. Takeda103A has the potential for the research of heart failure[1].

  • CAS Number: 865609-72-9
  • MF: C24H23F2N7O
  • MW: 463.48
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Curindolizine

Curindolizine, indolizine alkaloid , displays an anti-inflammatory action in lipopolyssacharide (LPS)-induced RAW 264.7 macrophages with an IC50 value of 5.31 μM[1].

  • CAS Number: 1899935-44-4
  • MF: C30H35N3O2
  • MW: 469.62
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CC260

CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Kis of 40 nM and 30 nM, respectively. CC260 does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. CC260 can be used for cell energy metabolism, diabetes and cancer research[1].

  • CAS Number: 2411088-26-9
  • MF: C24H29Cl2N5O2
  • MW: 490.43
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chloride ionophore IV

Chloride Ionophore IV is a thiourea type hydrogen bonding-based receptor. Chloride Ionophore IV is a chloride ionophore[1][2].

  • CAS Number: 187404-67-7
  • MF: C33H50N4OS2
  • MW: 582.90600
  • Catalog: Others
  • Density: 1.105g/cm3
  • Boiling Point: 597.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 314.9ºC

1,3-Dimethoxy(2H4)benzene

1,3-Dimethoxybenzene-d4 is the deuterium labeled 1,3-Dimethoxybenzene[1]. 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds[2].

  • CAS Number: 362049-44-3
  • MF: C8H6D4O2
  • MW: 142.188
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 217.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 87.8±0.0 °C

Baminercept

Baminercept (BG 9924) is a lymphotoxin β receptor IgG fusion protein (LTβR-Ig). Baminercept can be used for the research of many autoimmune diseases including primary Sjögren's syndrome (SS) and rheumatoid arthritis (RA) [1][2].

  • CAS Number: 909110-25-4
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyridine-d5

Pyridine-d5 is the deuterium labeled Pyridine[1].

  • CAS Number: 7291-22-7
  • MF: C5D5N
  • MW: 84.131
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 115.3±0.0 °C at 760 mmHg
  • Melting Point: -41ºC
  • Flash Point: 20.0±0.0 °C

Zerlasiran

Zerlasiran is an apolipoprotein A (ApoA) synthesis reducer[1].

  • CAS Number: 2646703-64-0
  • MF: C443H594N144O277P40S10
  • MW: 14155.81
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2,3,5,6-tetramethyl-benzenesulfonylamino)-acetic acid

((2,3,5,6-Tetramethylphenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 379250-94-9
  • MF: C12H17NO4S
  • MW: 271.33300
  • Catalog: Others
  • Density: 1.254g/cm3
  • Boiling Point: 486.8ºC at 760 mmHg
  • Melting Point: 166-167℃
  • Flash Point: 248.2ºC

SMND-309

SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. IC50 value:Target: SMND-309 mitigated the effects of ischemia and reperfusion injury on brain by decreasing the infract volume, improving neurological function, increasing the survival of neurons and promoting angiogenesis by increasing the levels of erythropoietin (EPO), erythropoietin receptor (EPOR), phosphorylated JAK2 (P-JAK2), phosphorylated STAT3 (P-STAT3), VEGF and VEGF receptor 2 (Flk-1) in the brain.

  • CAS Number: 1065559-56-9
  • MF: C18H14O8
  • MW: 358.29900
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,7,4'-Trihydroxy-8-methylflavanone

5,7,4'-Trihydroxy-8-Methylflavanone (Compound 2) is a flavanone isolated from Qualea grandiflora[1].

  • CAS Number: 916917-28-7
  • MF: C16H14O5
  • MW: 286.279
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 570.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.1±23.6 °C

Nicaraven

Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.

  • CAS Number: 79455-30-4
  • MF: C15H16N4O2
  • MW: 284.313
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 635.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 338.4±27.3 °C

Boc-D-Phg-OH

(αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]benzeneacetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 33125-05-2
  • MF: C13H17NO4
  • MW: 251.278
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 382.6±25.0 °C at 760 mmHg
  • Melting Point: 88-91 °C
  • Flash Point: 185.2±23.2 °C

Jaconine

Jaconine is a natural product that can be isolated from honey of the Ragwort (Senecio jacobaea)[1].

  • CAS Number: 480-75-1
  • MF: C18H26ClNO6
  • MW: 387.85500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beclamide

Beclamide is a drug that possesses anticonvulsant activity, has been used as a sedative and as an anticonvulsant.

  • CAS Number: 501-68-8
  • MF: C10H12ClNO
  • MW: 197.66100
  • Catalog: Neurological Disease
  • Density: 1.145g/cm3
  • Boiling Point: 386.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 187.8ºC

Diphenylterazine

Diphenylterazine is a bioluminescence agent.

  • CAS Number: 344940-63-2
  • MF: C25H19N3O
  • MW: 377.44
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Indecainid

Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent[1].

  • CAS Number: 73681-12-6
  • MF: C20H24N2O
  • MW: 308.41700
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Propionyl Glycine

Propionylglycine is a peptide[1].

  • CAS Number: 21709-90-0
  • MF: C5H9NO3
  • MW: 131.13
  • Catalog: Metabolic Disease
  • Density: 1.174g/cm3
  • Boiling Point: 382.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 185.2ºC

Yubeinine

Yubeinine is an alkaloid, isolated from the bulbs of Fritillaria yuminensis[1].

  • CAS Number: 157478-01-8
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trigonelline chloride

Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.

  • CAS Number: 6138-41-6
  • MF: C7H8ClNO2
  • MW: 173.597
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: ~260 °C (dec.)
  • Flash Point: N/A

N-Acetyl-L-isoleucine

(2S,3S)-2-Acetamido-3-methylpentanoic acid is an isoleucine derivative[1].

  • CAS Number: 3077-46-1
  • MF: C8H15NO3
  • MW: 173.210
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 369.6±25.0 °C at 760 mmHg
  • Melting Point: 147-154ºC
  • Flash Point: 177.4±23.2 °C

DEOXYNIVALENOL

Deoxynivalenol, a mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors[1].

  • CAS Number: 51481-10-8
  • MF: C15H20O6
  • MW: 296.316
  • Catalog: Metabolic Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 543.9±50.0 °C at 760 mmHg
  • Melting Point: 151-153ºC
  • Flash Point: 206.9±23.6 °C