Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Angiotensin I/II 1-6

Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

  • CAS Number: 47896-63-9
  • MF: C36H55N11O10
  • MW: 801.89
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sucralose

Sucralose is an intense organochlorine artificial sweetener.

  • CAS Number: 56038-13-2
  • MF: C12H19Cl3O8
  • MW: 397.634
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 669.4±55.0 °C at 760 mmHg
  • Melting Point: 125.5ºC
  • Flash Point: 358.7±31.5 °C

Yunaconitine

Yunaconitine(Guayewuanine B) is a highly toxic aconitum alkaloid.

  • CAS Number: 70578-24-4
  • MF: C35H49NO11
  • MW: 659.764
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 722.8±60.0 °C at 760 mmHg
  • Melting Point: 142-144ºC
  • Flash Point: 390.9±32.9 °C

H-Thr-Asp-OH

H-Thr-Asp-OH is a biologically active peptide.

  • CAS Number: 108320-97-4
  • MF: C8H14N2O6
  • MW: 234.20700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Theophyllol

Theophyllol (theophylline sodium acetate) can alter calcium levels in subcellular fractions of rat brain cortex[1].

  • CAS Number: 8002-89-9
  • MF: C9H11N4NaO4
  • MW: 284.18000
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 454.1°C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 228.4°C

Z-D-Asp(OtBu)-OH.H2O

Z-D-Asp(OtBu)-OH is an aspartic acid derivative[1].

  • CAS Number: 71449-08-6
  • MF: C16H23NO7
  • MW: 341.356
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 575.1ºC at 760 mmHg
  • Melting Point: 56.5-57.1°C
  • Flash Point: 301.6ºC

Acetyl Decapeptide-3

Ac-Decapeptide is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 935288-50-9
  • MF: C68H95N19O17
  • MW: 1450.599
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Blestriarene B

Blestriarene B ((-)-Blestriarene B) a stilbenoid isolated by the guidance of inhibitory effect of tubulin polymerization from the tubers of Bletilla striata (Orchidaceae)[1].

  • CAS Number: 127211-03-4
  • MF: C30H24O6
  • MW: 480.50800
  • Catalog: Others
  • Density: 1.407g/cm3
  • Boiling Point: 794.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 434.3ºC

Perisesaccharide B

Perisesaccharide B is an oligosaccharide isolated from the root barks of Periploca sepium.

  • CAS Number: 1095261-93-0
  • MF: C36H60O18
  • MW: 780.851
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 832.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 246.7±27.8 °C

Kaurenoic acid

Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway[1].

  • CAS Number: 6730-83-2
  • MF: C20H30O2
  • MW: 302.451
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 426.6±34.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.8±20.3 °C

6-Nitro(2H11)chrysene

6-Nitrochrysene-d11 is the deuterium labeled 6-Nitrochrysene[1].

  • CAS Number: 203805-92-9
  • MF: C18D11NO2
  • MW: 284.353
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 505.0±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 252.5±14.3 °C

SPT-IN-1

SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research[1].

  • CAS Number: 1933533-18-6
  • MF: C22H24N2O3
  • MW: 364.44
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Scoparil

Scoparinol (Scopadiol) is a diterpene isolated from Scoparia dulcis that has significant analgesic and anti-inflammatory activities[1].

  • CAS Number: 130838-00-5
  • MF: C27H38O4
  • MW: 426.588
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 544.3±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 173.8±18.1 °C

L-Isoleucine hydrochloride

L-Isoleucine hydrochloride is an isoleucine derivative[1].

  • CAS Number: 17694-98-3
  • MF: C6H14ClNO2
  • MW: 167.63400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phosal 50 PG

Phosal 50 PG is a standardized phosphatidylcholine concentrate, used in some lipid-based formulations to improve the absorption, effectiveness, and therapeutic index of the active ingredients[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tegomil fumarate

Tegomil fumarate is an immunomodulator[1].

  • CAS Number: 1817769-42-8
  • MF: C18H26O11
  • MW: 418.39
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Epigambogic acid

Epigambogic acid is a natural anti-tumor, antitussive, expectorant and anti-inflammatory compound[1][2].

  • CAS Number: 887606-04-4
  • MF: C38H44O8
  • MW: 628.75
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: 808.9±65.0 °C
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-Crosstide

Biotin-Crosstide is abiotinylated Crosstide (HY-P0315).

  • CAS Number: 923949-90-0
  • MF: C58H91N19O19S
  • MW: 1390.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-4-DEHYDRO-L-PROLINE METHYL ESTER

3,4-Dehydro-L-proline methyl ester hydrochloride is a proline derivative[1].

  • CAS Number: 51827-12-4
  • MF: C6H10ClNO2
  • MW: 163.60200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Paeonilactone C

Paeonilactone C is a monoterpenoid, that can be isolated from paeony root[1].

  • CAS Number: 98751-77-0
  • MF: C17H18O6
  • MW: 318.32
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 531.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.6±23.6 °C

DQP-997-74

DQP-997-74 (compound 2i) is a selective inhibitor of N-methyl-d-aspartate receptor (NMDAR), specifically targeting GluN2C/D (IC50: 0.069 μM and 0.035 μM), with Blood-brain permeability. Where DQP refers to dihydroquinoline-pyrazoline. DQP-997-74 acts synergistically with the agonist glutamate to exhibit time-dependent enhanced potency in inhibiting hypersynchronous activity driven by high-frequency excitatory synaptic transmission. DQP-997-74 reduces the number of epileptogenesis in a murine model of tuberous sclerosis complex (TSC)-induced epilepsy. DQP-997-74 can be used for research on NMDAR-related neurological diseases[1].

  • CAS Number: 2377187-09-0
  • MF: C28H19Cl2F2N3O4
  • MW: 570.37
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ser-Ala-OH

H-Ser-Ala-OH is a biologically active peptide.

  • CAS Number: 6403-17-4
  • MF: C6H12N2O4
  • MW: 176.17000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phenprocoumon

Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.

  • CAS Number: 435-97-2
  • MF: C18H16O3
  • MW: 280.318
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 463.2±45.0 °C at 760 mmHg
  • Melting Point: 179.5ºC
  • Flash Point: 195.7±21.5 °C

Isoacteoside

Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls.IC50 value:Target:In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 μM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 μM) and quercetin (IC50=7.2 μM).

  • CAS Number: 61303-13-7
  • MF: C29H36O15
  • MW: 624.587
  • Catalog: Metabolic Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 942.9±65.0 °C at 760 mmHg
  • Melting Point: 220-230℃
  • Flash Point: 306.1±27.8 °C

NSC 23005 sodium

NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.

  • CAS Number: 1796596-46-7
  • MF: C13H16NNaO4S
  • MW: 305.324
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Unguisin B

Unguisin B s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis[1].

  • CAS Number: 226956-07-6
  • MF: C37H56N8O7
  • MW: 724.890
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 1158.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 654.3±34.3 °C

L-Aspartic acid dibenzyl ester 4-toluenesulfonate

H-Asp(OBzl)-Obzl.TosOH is an aspartic acid derivative[1].

  • CAS Number: 2886-33-1
  • MF: C25H27NO7S
  • MW: 485.549
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 455.3ºC at 760 mmHg
  • Melting Point: 157-160 °C(lit.)
  • Flash Point: N/A

(D-Arg2)-Dermorphin (1-4) amide trifluoroacetate salt

[D-Arg2]Dermorphin-(1-4) amide is a N-terminal shorter peptide amide of [D-Arg2]dermorphin with the hypothermic effect. [D-Arg2]Dermorphin-(1-4) amide shows analgesic activity and degradation in soluble mouse liver and brain extracts[1].

  • CAS Number: 100304-60-7
  • MF: C26H36N8O5
  • MW: 540.61500
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B

3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B is a chemical constituent of the plant Poria cocos [1].

  • CAS Number: 1260252-18-3
  • MF: C41H64O14
  • MW: 780.938
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 807.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.9±27.8 °C

Benzenesulfonamide,N-[(cyclohexylamino)carbonyl]-4-methyl

Cyclamide (Cicloral), an oligopeptide, can be produced by cyanobacteria algae strains. Cyclamide can be used for the research of diabetes mellitus[1][2].

  • CAS Number: 664-95-9
  • MF: C14H20N2O3S
  • MW: 296.39
  • Catalog: Metabolic Disease
  • Density: 1.26g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A