Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4-Methylanisole-13C

4-Methylanisole-13C is the 13C-labeled 4-Methylanisole. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[1].

  • CAS Number: 117923-70-3
  • MF: C713CH10O
  • MW: 123.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Minimolide F

Minimolide F is a sesquiterpene lactone. Minimolide F has inhibitory activity against human nasopharyngeal cancer cells. Minimolide F can be used for the research of cancer[1].

  • CAS Number: 1367351-41-4
  • MF: C19H26O5
  • MW: 334.407
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 465.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 204.2±28.8 °C

1,1,3-Tribromoacetone

1,1,3-Tribromoacetone is an impurity of methotrexate[1]. Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1].

  • CAS Number: 3475-39-6
  • MF: C3H3Br3O
  • MW: 294.767
  • Catalog: Others
  • Density: 2.6±0.1 g/cm3
  • Boiling Point: 266.2±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 115.1±9.7 °C

((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine

((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine is a leucine derivative[1].

  • CAS Number: 1041437-99-3
  • MF: C12H15ClFNO4S
  • MW: 323.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SecinH3

SecinH3 is an antagonist of cytohesins with IC50s of 5.4 μM, 2.4 μM, 5.4 μM, 5.6 μM, 5.6 μM and 65 μM for hCyh1, hCyh2, mCyh3, hCyh3, drosophila steppke and yGea2-S7, respectively.

  • CAS Number: 853625-60-2
  • MF: C24H20N4O4S
  • MW: 460.505
  • Catalog: Endocrinology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-O-(2-Bromo-Cbz)-L-Tyrosine

(S)-3-(4-((((2-Bromobenzyl)oxy)carbonyl)oxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid is a tyrosine derivative[1].

  • CAS Number: 47689-67-8
  • MF: C22H24BrNO7
  • MW: 494.332
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 634.9±55.0 °C at 760 mmHg
  • Melting Point: 112-115ºC
  • Flash Point: 337.8±31.5 °C

HUHS015

HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. [1]

  • CAS Number: 1453097-13-6
  • MF: C19H18N4O
  • MW: 318.372
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 585.2±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 307.7±27.9 °C

8-Epiloganic acid

8-Epiloganic acid, an iridoid glucoside, can be found in Linaria cymbalaria (Scrophulariaceae)[1].

  • CAS Number: 82509-41-9
  • MF: C16H24O10
  • MW: 376.35600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 138-139 °C
  • Flash Point: N/A

DFMO

Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

  • CAS Number: 68278-23-9
  • MF: C6H13ClF2N2O2
  • MW: 236.645
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 347ºC at 760 mmHg
  • Melting Point: 181-184°C
  • Flash Point: 163.7ºC

BDP 630/650 Maleimide

BDP 630/650 maleimide is a fluorophore which can be read on the Cyanine5 channel. BDP 630/650 maleimide is useful for fluorescence lifetime related measurements because of the long life time of the excited state[1].

  • CAS Number: 2183473-31-4
  • MF: C29H23BF2N4O4S
  • MW: 572.390
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ser-Glu-OH

(S)-2-((S)-2-Amino-3-hydroxypropanamido)pentanedioic acid is a glutamic acid derivative[1].

  • CAS Number: 6403-16-3
  • MF: C8H14N2O6
  • MW: 234.20700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Propionyl-L-carnitine hydrochloride

Levocarnitine propionate hcl is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.

  • CAS Number: 119793-66-7
  • MF: C10H20ClNO4
  • MW: 253.723
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 165-167°C
  • Flash Point: N/A

Methyl 3-(2H4)pyridinecarboxylate

Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate[1]. Methyl nicotinate, the methyl ester of Niacin found in alcoholic beverages, that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain[2].

  • CAS Number: 345909-99-1
  • MF: C7H3D4NO2
  • MW: 141.161
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 209.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 95.6±0.0 °C

Bilaid B1

Bilaid B1 (Compound Bilaid 2b) is an analgesics compound[1]

  • CAS Number: 2393866-07-2
  • MF: C28H39N5O5
  • MW: 525.640
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 895.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 495.7±34.3 °C

Unguisin A

Unguisin A s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis[1].

  • CAS Number: 226956-06-5
  • MF: C40H54N8O7
  • MW: 758.906
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 1202.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 681.3±34.3 °C

Z433927330

Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1].

  • CAS Number: 1005883-72-6
  • MF: C20H20N4O3
  • MW: 364.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Thr-OH

Z-Thr-OH is a threonine derivative[1].

  • CAS Number: 19728-63-3
  • MF: C12H15NO5
  • MW: 253.251
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 483.7±45.0 °C at 760 mmHg
  • Melting Point: 101-103 °C(lit.)
  • Flash Point: 246.3±28.7 °C

3,7,25-Trihydroxycucurbita-5,23-dien-19-al

3,7,25-Trihydroxycucurbita-5,23-dien-19-al (TCD) is a natural product, that can be isolated from the chloroform extract of the leaves of Momordica foetida[1].

  • CAS Number: 85372-65-2
  • MF: C30H48O4
  • MW: 472.7
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Guanosine-13C10,15N5 ammonium

Guanosine-13C10,15N5 (ammonium) is the 13C and 15N labeled Guanosine ammonium[1].

  • CAS Number: 2483830-19-7
  • MF: 13C10H28N415N5O13P3
  • MW: 590.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ADAMTS-5-IN-2

ADAMTS-5-IN-2 (compound 25) is a potent ADAMTS-5 inhibitor with an IC50 value of 0.71 µM. ADAMTS-5-IN-2 has the potential for the research of modifying osteoarthritis[1][2].

  • CAS Number: 294648-66-1
  • MF: C17H15N3OS
  • MW: 309.39
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(±)-Camphor

(-)-Camphor is a natural product that can be isolated from A. rnexicana[1].

  • CAS Number: 464-48-2
  • MF: C10H16O
  • MW: 152.233
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 207.4±0.0 °C at 760 mmHg
  • Melting Point: 178-180ºC
  • Flash Point: 64.4±0.0 °C

Lutein dimyristate

Lutein dimyristate possesses pro-oxidant activity[1].

  • CAS Number: 86853-02-3
  • MF: C68H108O4
  • MW: 989.58
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3'-Amino-3'-deoxyadenosine

3'-Amino-3'-deoxyadenosine is an antitumor agent extracted from Helminthosporium[1].

  • CAS Number: 2504-55-4
  • MF: C10H14N6O3
  • MW: 266.25700
  • Catalog: Cancer
  • Density: 2.08g/cm3
  • Boiling Point: 657.6ºC at 760 mmHg
  • Melting Point: 260-261 °C
  • Flash Point: 351.5ºC

Succinaldehydic acid

Succinaldehydic acid is a catabolite of GABA.

  • CAS Number: 692-29-5
  • MF: C4H6O3
  • MW: 102.089
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 248.6±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 118.4±19.1 °C

Amyloid β-Protein (1-40) (scrambled) trifluoroacetate salt

Scrambled β-amyloid (1-40) is a biological active peptide. (A? (1-40) together with A? (1-42) are two major C-terminal variants of the A? protein constituting the majority of A?s. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain. This peptide is the scrambled sequence of Abeta 1-40 HY-P0265)

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LY88074

LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner[1].

  • CAS Number: 177744-96-6
  • MF: C21H14O4S
  • MW: 346.39900
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Arabinopyranose

D-Arabinose, a monosaccharide, shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM[1].

  • CAS Number: 28697-53-2
  • MF: C5H10O5
  • MW: 150.130
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 333.2±42.0 °C at 760 mmHg
  • Melting Point: 152-160ºC
  • Flash Point: 155.3±27.9 °C

[Tyr0] Corticotropin Releasing Factor, ovine

[Tyr0] Corticotropin Releasing Factor, ovine is a corticotropin releasing factor/hormone isolated from ovine. Corticotropin releasing factor (CRF) is a hypothalamic hormone, stimulates the release of adrenocorticotropic hormone (ACTH) and of β-endorphin[1][2].

  • CAS Number: 83930-34-1
  • MF: C214H348N60O65S1
  • MW: 4833.48
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kaempferol 3-O-rutinoside 7-O-glucoside

Kaempferol 3-O-rutinoside 7-O-glucoside is a flavonoid glycoside from red tomato[1].

  • CAS Number: 34336-18-0
  • MF: C33H40O20
  • MW: 756.65900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R)-Amino(3,5-dinitrophenyl)acetic acid

(2R)-2-[(3,5-Dinitrobenzoyl)amino]-2-phenyl-acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 74927-72-3
  • MF: C15H11N3O7
  • MW: 241.158
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 421.4±45.0 °C at 760 mmHg
  • Melting Point: 217-218 °C (dec.)
  • Flash Point: 208.6±28.7 °C