Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Beryllon II

Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins.

  • CAS Number: 51550-25-5
  • MF: C20H10N2Na4O15S4
  • MW: 738.517
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Byakangelicin

(Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM[1].

  • CAS Number: 19573-01-4
  • MF: C17H18O7
  • MW: 334.321
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 571.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 299.4±30.1 °C

3(20)-Phytene-1,2-diol

7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is a terpenoid that can be isolated from Eupatorium fortunei. 7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is used in dropsy, chill, and fever research[1].

  • CAS Number: 438536-34-6
  • MF: C20H40O2
  • MW: 312.53
  • Catalog: Infection
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 425.5±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 179.3±17.8 °C

2-Methoxypyrazine-d3

2-Methoxypyrazine-d3 is the deuterium labeled 2-Methoxypyrazine[1]. 2-Methoxypyrazine is an active compound. 2-Methoxypyrazine can be used for the research of various biochemical studies[2].

  • CAS Number: 32046-21-2
  • MF: C5H3D3N2O
  • MW: 113.13200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

preisocalamendiol

Preisocalamendiol is a plausible precursor of isocalamendiol. Preisocalamendiol can be isolated from Acorus calamus L[1].

  • CAS Number: 25645-19-6
  • MF: C15H24O
  • MW: 220.350
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 315.0±41.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 129.9±22.6 °C

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine is a natural product that can be isolated from Lycium ruthenicum Murr.[1].

  • CAS Number: 1698873-84-5
  • MF: C25H33N3O6
  • MW: 471.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Methoxycoumarin

Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.

  • CAS Number: 531-59-9
  • MF: C10H8O3
  • MW: 176.169
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 335.3±37.0 °C at 760 mmHg
  • Melting Point: 117-121 °C(lit.)
  • Flash Point: 138.6±21.1 °C

di-(1-pyrenylmethyl)ether

(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes[1].

  • CAS Number: 74833-81-1
  • MF: C34H22O
  • MW: 446.53800
  • Catalog: Others
  • Density: 1.335g/cm3
  • Boiling Point: 671.9ºC at 760 mmHg
  • Melting Point: 169-170ºC
  • Flash Point: 408.8ºC

(R)-2-HYDROXYBUTYRIC ACID

(R)-2-Hydroxybutanoic acid is the inactive isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1].

  • CAS Number: 20016-85-7
  • MF: C4H8O3
  • MW: 104.10
  • Catalog: Metabolic Disease
  • Density: 1.195g/cm3
  • Boiling Point: 238.3ºC at 760 mmHg
  • Melting Point: 50-54ºC
  • Flash Point: 112.2ºC

Antitumor photosensitizer-1

Antitumor photosensitizer-1 (Compound 8) is a potent photosensitizer. Antitumor photosensitizer-1 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new drug candidates for photodynamic research[1].

  • CAS Number: 2344751-89-7
  • MF: C42H51N5O6
  • MW: 721.88
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-p-Coumaroylquinic acid

3-p-Coumaroylquinic acid (compound 3a) is an isomer of p-coumaroylquinic acid[1].

  • CAS Number: 1899-30-5
  • MF: C16H18O8
  • MW: 338.30900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

hiCE inhibitor-1

hiCE inhibitor-1, a sulfonamide derivative, is a selective human intestinal enzyme (hiCE) inhibitor with a Ki value of 53.3 nM. hiCE inhibitor-1 can be used to improve Irinotecan (HY-16562)-induced diarrhoea[1].

  • CAS Number: 2654-68-4
  • MF: C18H14Cl2N2O4S2
  • MW: 457.35
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

XF056-132

XF056-132 is the salt form of trifluoroacetic acid (TFA, HY-21182).

  • CAS Number: 2694057-55-9
  • MF: C53H58F7N9O9S
  • MW: 1130.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-N-methyl-L-leucine

Boc-N-Me-Leu-OH is a leucine derivative[1].

  • CAS Number: 53363-89-6
  • MF: C12H23NO4
  • MW: 245.315
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 338.2±21.0 °C at 760 mmHg
  • Melting Point: 55-60 ℃
  • Flash Point: 158.3±22.1 °C

Tyrosylvaline

Tyrosylvaline is a biologically active peptide.

  • CAS Number: 17355-09-8
  • MF: C14H20N2O4
  • MW: 280.32000
  • Catalog: Others
  • Density: 1.245 g/cm3
  • Boiling Point: 572ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 299.7ºC

Lucidenic acid D2

Lucidenic acid D (Lucidenic acid D2), isolated from the gills of Ganoderma lucidum, is a highly oxidized lanostane-type triterpenoid[1].

  • CAS Number: 98665-16-8
  • MF: C29H38O8
  • MW: 514.60700
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Caffeoyl-Coenzym A

Caffeoyl-CoAcould be isolated from leaf tissues of Gramineae with a Km value of 1.45 μM[1].

  • CAS Number: 53034-79-0
  • MF: C30H42N7O19P3S
  • MW: 929.67600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4'-Demethylpodophyllotoxone

4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823)[1].

  • CAS Number: 93780-84-8
  • MF: C21H18O8
  • MW: 398.36300
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Precyasterone

Precyasterone is a natural product isolated from the dried roots of Cyathula capitata[1].

  • CAS Number: 27335-85-9
  • MF: C29H44O8
  • MW: 520.655
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 726.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 235.9±26.4 °C

Glucarpidase

Glucarpidase is an enzyme that inactivates methotrexate. Glucarpidase can be used for renal dysfunction diseases research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Actarit

Actarit, an orally active antirheumatic compound, has the potential to treat type II collagen-induced arthritis[1].

  • CAS Number: 18699-02-0
  • MF: C10H11NO3
  • MW: 193.199
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 449.1±28.0 °C at 760 mmHg
  • Melting Point: 173-175°C
  • Flash Point: 225.4±24.0 °C

Pilloin

Pilloin, a flavonoid isolated from Marrubium cylleneum, exerts a cytotoxic action targeted at the transformed lymphoblasts. Pilloin also possesses anti-inflammatory activity[1].

  • CAS Number: 32174-62-2
  • MF: C17H14O6
  • MW: 314.289
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 569.6±50.0 °C at 760 mmHg
  • Melting Point: 230-232℃ (Decomposition) (methanol )
  • Flash Point: 213.9±23.6 °C

Iso-oxypeucedanin

Iso-oxypeucedanin is a coumarin found in Angelica dahurica.

  • CAS Number: 5058-15-1
  • MF: C16H14O5
  • MW: 286.27900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PG-11047 tetrahydrochloride

PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].

  • CAS Number: 206991-64-2
  • MF: C14H36Cl4N4
  • MW: 402.27
  • Catalog: Cancer
  • Density: 0.888g/cm3
  • Boiling Point: 367.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 178.3ºC

Dimethyl phthalate

Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].

  • CAS Number: 131-11-3
  • MF: C10H10O4
  • MW: 194.184
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 282.7±8.0 °C at 760 mmHg
  • Melting Point: 2 °C(lit.)
  • Flash Point: 146.1±0.0 °C

Senkyunolide

Senkyunolide A, isolated from Ligusticum chuanxiong Hort, has cytoprotective and antiproliferative activities. Anti-tumor activity[1][2].

  • CAS Number: 63038-10-8
  • MF: C12H16O2
  • MW: 192.254
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 368.1±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 154.2±16.7 °C

5-Iso-ZnAF-1

ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry[1].

  • CAS Number: 321859-09-0
  • MF: C34H28N4O5
  • MW: 572.61000
  • Catalog: Others
  • Density: 1.443g/cm3
  • Boiling Point: 844.065ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 464.274ºC

BI-3812

BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.

  • CAS Number: 2166387-64-8
  • MF: C26H32ClN7O5
  • MW: 558.03
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BOC-HYP-OL

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate is a proline derivative[1].

  • CAS Number: 61478-26-0
  • MF: C10H19NO4
  • MW: 217.262
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 340.3±27.0 °C at 760 mmHg
  • Melting Point: 81-86 °C(lit.)
  • Flash Point: 159.6±23.7 °C

L-β-Homoalanine hydrochloride

L-beta-Homoalanine hydrochloride is an alanine derivative[1].

  • CAS Number: 58610-41-6
  • MF: C10H14ClNO2
  • MW: 215.677
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 223.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 89ºC