Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

3,4,5,2',4'-Pentahydroxychalcone

Robtein is a flavone that can be isolated from Robinia pseudoacacia[1].

  • CAS Number: 2679-65-4
  • MF: C15H12O6
  • MW: 288.252
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 658.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 365.8±28.0 °C

2,5-Dimethoxybenzoic acid

2,5-Dimethoxybenzoic acid is an intermediate used in the synthesis of the galbulimima alkaloid GB 13[1].

  • CAS Number: 2785-98-0
  • MF: C9H10O4
  • MW: 182.173
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 329.5±22.0 °C at 760 mmHg
  • Melting Point: 74-78 °C
  • Flash Point: 133.6±15.8 °C

n(alpha)-(2 4-dinitro-5-fluorophenyl)-

Nα-(2,4-Dinitro-5-fluorophenyl)-D-valinamide is a valine derivative[1].

  • CAS Number: 210529-62-7
  • MF: C11H13FN4O5
  • MW: 300.24300
  • Catalog: Others
  • Density: 1.469g/cm3
  • Boiling Point: 537.5ºC at 760 mmHg
  • Melting Point: 173-177ºC
  • Flash Point: 278.9ºC

Norgestimate

Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2].

  • CAS Number: 35189-28-7
  • MF: C23H31NO3
  • MW: 369.497
  • Catalog: Endocrinology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 497.9±45.0 °C at 760 mmHg
  • Melting Point: 216ºC
  • Flash Point: 254.9±28.7 °C

15,16-Epoxy-12S-hydroxylabda-8(17),13(16),14-triene

15,16-Epoxy-12-hydroxylabda-8(17),13(16),14-triene (compound 6) is a furanolabdane hydroxide compound[1].

  • CAS Number: 216011-55-1
  • MF: C20H30O2
  • MW: 302.45
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 328.6±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 152.5±18.7 °C

C15 Glucosyl(β) ceramide-d7

C15 Glucosyl(β) ceramide-d7 is deuterium labeled C15 Glucosyl(β) ceramide.

  • CAS Number: 2315262-18-9
  • MF: C39H68D7NO8
  • MW: 693.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Procyanidin A5'

Procyanidin A5' is A dimerized proanthocyanidin type A[1].

  • CAS Number: 111466-30-9
  • MF: C30H24O12
  • MW: 576.50400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethotoin

Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin[1].

  • CAS Number: 86-35-1
  • MF: C11H12N2O2
  • MW: 204.22500
  • Catalog: HBV
  • Density: 1.197 g/cm1.197 g/cm3
  • Boiling Point: 342.72°C (rough estimate)
  • Melting Point: 94ºC
  • Flash Point: N/A

Isorubrofusarin 10-gentiobioside

Isorubrofusarin-6-O-β-gentiobioside (Isorubrofusarin gentiobioside) is a naphthopyrone glycoside isolated from Cassia obtusifolia Linn seeds[1].

  • CAS Number: 200127-93-1
  • MF: C27H32O15
  • MW: 596.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calconcarboxylic acid

Calconcarboxylic acid, an azo dye, is a silver-ion sensitizer. Calconcarboxylic acid can be used for detection of proteins on polyacrylamide gels[1][2].

  • CAS Number: 3737-95-9
  • MF: C21H14N2O7S
  • MW: 438.410
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 300 °C(lit.)
  • Flash Point: N/A

Oestradiol 17-heptanoate

Estradiol enanthate is a shorter-acting estrogen. The combination of Estradiol enanthate and dihydroxyprogesterone acetophenide can be used as a monthly injectable contraceptive[1][2].

  • CAS Number: 4956-37-0
  • MF: C25H36O3
  • MW: 384.552
  • Catalog: Endocrinology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 509.5±50.0 °C at 760 mmHg
  • Melting Point: 94-96ºC
  • Flash Point: 197.1±22.9 °C

Hexyl acrylate

Hexyl acrylate is a an initiator in Photo-initiated CVD[1].

  • CAS Number: 2499-95-8
  • MF: C9H16O2
  • MW: 156.222
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 191.6±9.0 °C at 760 mmHg
  • Melting Point: -45°C
  • Flash Point: 58.3±12.0 °C

N-acetyl-L-methionine

N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development[1].

  • CAS Number: 65-82-7
  • MF: C7H13NO3S
  • MW: 191.248
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 371.3±52.0 °C at 760 mmHg
  • Melting Point: 104-107ºC
  • Flash Point: 178.3±30.7 °C

(D-Leu7)-LHRH trifluoroacetate salt

(D-Leu7)-LHRH is a biologically active peptide.

  • CAS Number: 53728-75-9
  • MF: C55H75N17O13
  • MW: 1182.29000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Felbinac

Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

  • CAS Number: 5728-52-9
  • MF: C14H12O2
  • MW: 212.244
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 389.8±21.0 °C at 760 mmHg
  • Melting Point: 159-160 °C(lit.)
  • Flash Point: 286.6±17.2 °C

3-Nitro-D-phenylalanine

(R)-2-Amino-3-(3-nitrophenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 169530-97-6
  • MF: C9H10N2O4
  • MW: 210.187
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 410.8±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.3±25.9 °C

L-Glutamic acid:Hcl (17O4)

(S)-2-aminopentanedioic acid hydrochloride is a glutamic acid derivative[1].

  • CAS Number: 138-15-8
  • MF: C5H10ClNO4
  • MW: 183.590
  • Catalog: Others
  • Density: 1.525
  • Boiling Point: 333.8ºC at 760 mmHg
  • Melting Point: 214 °C (dec.)(lit.)
  • Flash Point: 155.7ºC

PIPENDOXIFENE

Pipendoxifene is a selective estrogen receptor modulator (SERM).

  • CAS Number: 198480-55-6
  • MF: C29H32N2O3
  • MW: 456.58
  • Catalog: Cancer
  • Density: 1.2g/cm3
  • Boiling Point: 685.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 368.6ºC

4-Methoxybenzylamine-d3

4-Methoxybenzylamine-d3 is the deuterium labeled Fmoc-Ser(tBu)-OH[1].

  • CAS Number: 2289707-21-5
  • MF: C8H8D3NO
  • MW: 140.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

A031

A031 is a highly effective PROTAC androgen receptor (AR) degrader with an IC50 value less than 0.25 μM for AR protein degradation. A031 has an inhibitory effect on tumor growth in zebrafish with human prostate cancer (VCaP)[1].

  • CAS Number: 2682255-44-1
  • MF: C50H61ClN10O7S
  • MW: 981.60
  • Catalog: PROTAC
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sulesomab

Sulesomab (IMMU-MN3) is a murine monoclonal antibody fragment of the IgG1 class that binds to Normal Cross-Reactive Antigen-90 present on leukocytes. Sulesomab is cleared into infection nonspecifically through increased capillary membrane permeability[1].

  • CAS Number: 167747-19-5
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dipsanoside B

Dipsanoside B is a novel tetrairidoid glucoside from Dipsacus asper. Dipsacus asper Wall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissiparism promoter of the osseous cells, and as an embryo security agent, etc[1].

  • CAS Number: 889678-64-2
  • MF: C66H90O37
  • MW: 1475.399
  • Catalog: Others
  • Density: 1.6±0.0 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isodonal

Isodonal is a N-pentane diterpene compound with potential cytotoxic, antitumor, inhibitory oxidative phosphorylation and antiingestion activities. Isodonal can be isolated from the leaves of Isodon wikstroemioides and is used in the study of gastrointestinal diseases, anti-tumor and anti-inflammatory[1].

  • CAS Number: 16964-56-0
  • MF: C22H28O7
  • MW: 404.45
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Transketolase-IN-3

Transketolase-IN-3 is a potent transketolase (TK) inhibitor. Transketolase-IN-3 has herbicidal activity and has inhibitory effects against Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). Transketolase-IN-3 can be used for the research of herbicides[1].

  • CAS Number: 2757552-03-5
  • MF: C20H9ClF3NO3
  • MW: 403.74
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AP1867

AP1867 is a synthetic FKBP12F36V-directed ligand.

  • CAS Number: 195514-23-9
  • MF: C38H47NO11
  • MW: 693.78
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BDP 630/650 azide

BDP 630/650 azide is a bright and photostable dye azide (BDP 630/650: Ex=630 nm, Em=650 nm). BDP 630/650 azide can be used for labeling using Click chemistry.

  • CAS Number: 2183473-22-3
  • MF: C26H23BF2N6O2S
  • MW: 532.373
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Rutarensin

Rutarensin is a phenolic compound found in Ruta chalepensis cell culture[1].

  • CAS Number: 119179-04-3
  • MF: C31H30O16
  • MW: 658.56000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Glu(OcHex)-OH

H-Glu(OcHex)-OH is a glutamic acid derivative[1].

  • CAS Number: 112471-82-6
  • MF: C11H19NO4
  • MW: 229.273
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 400.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.2±27.3 °C

BuChE-IN-4

BuChE-IN-4 (Compound C6) is a potent inhibitor of BuChE with an IC50 of 7.7 nM. BuChE-IN-4 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity[1].

  • CAS Number: 2499490-52-5
  • MF: C21H21BrFN3O4S
  • MW: 510.38
  • Catalog: AChE
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganglioside GD3 disodium salt

Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].

  • CAS Number: 497932-19-1
  • MF: C70H123N3Na2O29
  • MW: 1516.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A