Modified MMAF, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). Modified MMAF can be used for the targeted treatment of cancer[1].
Sodium diethylglycinate is a Glycine (HY-Y0966) derivative[1].
Bryonamide A is a natural compound isolated from red algae Bostrychia radicans (Rhodomelaceae)[1].
H-D-Glu(OBzl)-OH is a glutamic acid derivative[1].
Droxicainide is an antiarrhythmic agent.
(+)-Guaiacin is a compound extracted of the bark of Machilus wangchiana Chun. (Lauraceae). (+)-Guaiacin shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-activating factor (PAF) [1].
RM-581, an aminosteroid derivative, has potent anticancer activity in different types of cancer, including high fatality pancreatic cancer[1].
LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), corresponds to amino acids 61-80. LCMV GP (61-80) is a specific epitope which can induce CD4+ T-cell response[1][2][3].
AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity[1].
Fmoc-Ser(Trt)-OH is a serine derivative[1].
Faradiol is a triterpenoid. Faradiol can be isolated from the aerial parts of Dittrichia viscose[1].
2-Aminopurine-O-Ph-NHCO-C3-NHS ester (BG-GLA-NHS) is an amine-reactive building block. 2-Aminopurine-O-Ph-NHCO-C3-NHS ester can be used to modify viral capsids surface, and the synthesis of SNAP-tag substrates[1].
Cryptomeridiol can be isolated from Phaulopsis imbricata. Cryptomeridiol has melanogenesis inhibitory activity in the α-MSH-stimulated B16 melanoma cells[1].
Ethyl 2-oxo-4-phenylbutanoate-d5 is the deuterium labeled Ethyl 2-oxo-4-phenylbutanoate[1].
1-Dehydroxy-23-deoxojessic acid (compound 10) is a cycloartane-type triterpene. 1-Dehydroxy-23-deoxojessic acid exhibits cytotoxicity against murine colon 26-L5 carcinoma cells, with an EC50 of 62.38 μM[1].
6-(3,4,5-Trimethoxybenzamido)hexanoic acid is an antiarrythmic agent[1].
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative[1].
H-Thr-Met-OH is a biologically active peptide.
Quercetin 3-O-rutinoside-7-O-glucoside (compound 8) is an antioxidant agent that canbe found in Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside shows strong lipid peroxidation inhibitory activities[1].
Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).
Aclacinomycin A hydrochloride (Aclarubicin hydrochloride), a fluorescent molecule, is an effective anthracycline chemotherapeutic agent for hematologic cancers and solid tumors. Accumulates efficiently in the mitochondria of living human cells and leads to mitochondrial dysfunction[1].
PEN (human) is an endogenous peptide GPR83 agonist.
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells[1].
N-Nitrosodicyclohexylamine (NDCHA) is a N-nitrosocompound with anti-androgenic activities. N-Nitrosodicyclohexylamine shows the competitive binding to androgen receptor (AR) against 5α-dihydrotestosterone and decreased the level of AR protein[1].
Glutaminase-IN-1, a CB839 derivative, is an allosteric inhibitor of 1,3,4-selenadiazole-containing kidney-type glutaminase (KGA), with an IC50 of 1 nM. Glutaminase-IN-1 shows improved cellular uptake and antitumor activity.
1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].
(S)-Campesterol-d6 is deuterium labeled (S)-Campesterol.
Advantame is a non-caloric artificial sweetener, analogue of aspartame, commonly used as a food additive[1].
β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex[1].