L-Glutamic γ-monohydroxamate is an antitumor agent, inhibits cell proliferation. L-Glutamic γ-monohydroxamate selectively inhibits the uptake of L-histidine into microvascular endothelial cell. L-Glutamic γ-monohydroxamate, as a vanadium ligand, activates glucose uptake and metabolism, thus decreases the blood glucose levels in vivo[1][2][3].
Regaloside F is a phenolic glycerol glucoside that can be found in Lily bulbs[1].
4-Methylumbelliferyl-β-D-xylopyranoside (MuX) can be used as substrate for the research of β-Xylosidase activity. 4-Methylumbelliferyl-β-D-xylopyranoside shows burst, steady-state kinetics, which supports the conclusion that hydrolysis of the glycosidic bonds for the substrate 4-Methylumbelliferyl-β-D-xylopyranoside is rapid[1][2].
1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker which can be used to fabricate some electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is commonly found in organic chemistry or biochemistry where it is used as an activating reagent for carboxylic acids[1][2].
D-Alanyl-L-leucine (D-Ala-Leu) is a dipeptide that acts as a source donor of L-Leucine (HY-N0486)[1].
Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa[1].
1-(tert-Butyl) 5-methyl L-glutamate hydrochloride is a glutamic acid derivative[1].
MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].
Olivil-4'-O-β-glucopyranoside (Compound 2) is a lignin derived from Jasminum tortuosum stems[1].
ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].
Dimethylsulfonazo III is a potent sulfate indicator. Dimethylsulfonazo III can be used as indicator to test those samples contaminated with potassium or phosphate ions[1][2].
Cytidine 5'-triphosphate (ammonium salt)-d2 is the deuterium labeled Cytidine 5'-triphosphate ammonium salt[1].
BX341 is an anti-androgen.
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene (Compound 4) is a reaction product of Raloxifene with tertbutyldimethylsilyl chloride. 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is used to synthesize Raloxifene 6-glucuronide[1].
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].
WAY-313356 is an active molecule.
Loperamide-d6 is the deuterium labeled Loperamide[1].
1,1,1,2-Tetrachloroethane-d2 is the deuterium labeled 1,1,1,2-Tetrachloroethane[1].
ER proteostasis regulator-1 (compound 481) is a potent ER proteostasis regulator. ER proteostasis regulator-1 has the potential for the research of Alzheimer's disease and diabetes[1].
Orientin-2''-O-p-trans-coumarate is a flavonoid found in Trigonella foenum-graecum, with potent antioxidant activity[1].
5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride), a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU hydrochloride forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxal and methylglyoxal, which are derived from other metabolic pathways[1][2][3].
Histone H3 (1-35) is a 35-residue peptide of histone H3. Histone H3 is one of the five main histones involved in the structure of chromatin in eukaryotic cells[1].
Mefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research[1].
Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].
N6-Propionyl-L-lysine is a lysine derivative[1].
Fructosyl amino acid oxidase can be used to measure glycosylated protein. Glycosylated protein, especially glycosylated hemoglobin A1c, is an important marker to evaluate the efficacy of diabetes treatment[1].
(Rac)-Shikonin (Shikonin) possesses anti-tumor activity. (Rac)-Shikonin (Shikonin) circumvents cancer drug resistance by induction of a necroptotic death[1][2].
Spironolactone is a potent antagonist of the androgen receptor. Target: Androgen ReceptorSpironolactone is a potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. 5% topical spironolactone cream acts as an antiandrogen in human sebaceous glands, competing with DHT receptors and producing a decrease of labelled DHT. At the concentrations used the effect has been only local. No side-effects were recorded during both studies [1]. Patients who received spironolactone had a significant improvement in the symptoms of heart failure, as assessed on the basis of the New York Heart Association functional class (P<0.001). Gynecomastia or breast pain was reported in 10 percent of men who were treated with spironolactone, as compared with 1 percent of men in the placebo group (P<0.001). The incidence of serious hyperkalemia was minimal in both groups of patients [2].
Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents.