Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

T-F-Q-A-Y-P-L-R-E-A

T-F-Q-A-Y-P-L-R-E-A is a peptide. T-F-Q-A-Y-P-L-R-E-A can be used for the research of various biochemical[1].

  • CAS Number: 117592-22-0
  • MF: C55H82N14O16
  • MW: 1195.32000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tinospinoside C

Tinospinoside C (compound 5) is a diterpene. Tinospinoside C has cytotoxic and antifouling activities[1].

  • CAS Number: 1383977-51-2
  • MF: C27H36O12
  • MW: 552.57
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 742.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 403.1±32.9 °C

Adenosine, 2-chloro-2'-C-Methyl

2-Chloro-2′-β-C-methyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 205171-11-5
  • MF: C11H14ClN5O4
  • MW: 315.71
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 572.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.1±32.9 °C

Adenylate

Adenylate (Adk), i.e., myokinase, is a phosphotransferase enzyme, is often used in biochemical studies. Adenylate catalyzes the interconversion of adenosine phosphates. Adenylate monitors phosphate nucleotide levels inside the cell, it plays an important role in cellular energy homeostasis[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-GMCA

GMCA is a natural product isolated from Matricaria chamomilla[1].

  • CAS Number: 31564-49-5
  • MF: C16H20O9
  • MW: 356.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

O-NITROPHENYL STEARATE

2-Nitrophenyl stearate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 104809-27-0
  • MF: C24H39NO4
  • MW: 405.57100
  • Catalog: Others
  • Density: 1.006g/cm3
  • Boiling Point: 504.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 161.1ºC

Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK[1].

  • CAS Number: 209323-98-8
  • MF: C107H173N35O21S2
  • MW: 2349.87000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AT2R antagonist 1

AT2R antagonist 1 (compound 21) is a potent and high selective AT2R (angiotensin II AT2 receptor) ligand. AT2R antagonist 1 exhibits a fair AT2R affinity, with a Ki of 29 nM. AT2R antagonist 1 also inhibits common drug-metabolizing CYP enzymes. AT2R antagonist 1 shows high stability in human, rat and mouse liver microsomes[1].

  • CAS Number: 2709031-17-2
  • MF: C23H30N4O4S2
  • MW: 490.64
  • Catalog: Angiotensin Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Direct Blue 14

Diphenyl Blue (Direct Blue 14) is used as reference dye for group of azo dye.

  • CAS Number: 72-57-1
  • MF: C34H24N6Na4O14S4
  • MW: 960.805
  • Catalog: Dye Reagents
  • Density: 1.007 g/mL at 20 °C
  • Boiling Point: N/A
  • Melting Point: >300 °C(lit.)
  • Flash Point: N/A

Methyl 3-(4-Methoxybenzylamino)propanoate

N-(4-Methoxybenzyl)-b-alanine methyl ester is an alanine derivative[1].

  • CAS Number: 55383-92-1
  • MF: C12H17NO3
  • MW: 223.26800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-Corey lactone diol

(-)-Corey lactone diol is a reduced version of corey aldehyde. A building block in the chemical synthesis.

  • CAS Number: 32233-40-2
  • MF: C8H12O4
  • MW: 172.178
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 406.6±25.0 °C at 760 mmHg
  • Melting Point: 117-119 °C(lit.)
  • Flash Point: 172.9±16.7 °C

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a dipeptide[1].

  • CAS Number: 1262308-49-5
  • MF: C24H26N2O6
  • MW: 438.47300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI)

2-Trifluoromethyl adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 4627-40-1
  • MF: C11H12F3N5O4
  • MW: 335.24
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 2.11g/cm3
  • Boiling Point: 462.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 233.4ºC

Adenylyl cyclase-IN-1

Adenylyl cyclase-IN-1 is an adenylyl cyclase inhibitor with potential use in ocular hypotonia research[1].

  • CAS Number: 731827-16-0
  • MF: C9H8N2S3
  • MW: 240.37
  • Catalog: Adenylate Cyclase
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 352.5±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 167.0±25.9 °C

20-O-Acetylingenol-3-angelate

20-O-Acetylingenol-3-angelate is a natural compound.

  • CAS Number: 82425-35-2
  • MF: C27H36O7
  • MW: 472.57
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 603.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 318.6±31.5 °C

L-(+)-Ergothioneine

Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].

  • CAS Number: 497-30-3
  • MF: C9H15N3O2S
  • MW: 229.299
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 275-277ºC (dec.)
  • Flash Point: N/A

N,N,N-Triethylethanaminium perchlorate

Tetraethylammonium Perchlorate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 2567-83-1
  • MF: C8H20ClNO4
  • MW: 229.702
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300°C
  • Flash Point: N/A

Octadecane-1-thiol-d37

Octadecane-1-thiol-d37 is the deuterium labeled Octadecane-1-thiol[1].

  • CAS Number: 668433-57-6
  • MF: C18HD37S
  • MW: 323.78700
  • Catalog: Others
  • Density: 0.953g/cm3
  • Boiling Point: 360.502ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

hexaethylene glycol monohexadecyl ether

Hexaethylene glycol monohexadecyl ether is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 5168-91-2
  • MF: C28H58O7
  • MW: 506.75600
  • Catalog: Others
  • Density: 0.962 g/cm3
  • Boiling Point: 567.6ºC at 760mmHg
  • Melting Point: 39-40ºC
  • Flash Point: 297.1ºC

Globoside synthetase

Globoside synthetase (Gb4 synthetase) expressed by mature/activated B cells[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Hydroxy Carbofuran-d3

3-Hydroxycarbofuran-d3 is a deuterium labeled compound.

  • CAS Number: 1794759-59-3
  • MF: C12H12D3NO4
  • MW: 240.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TES (buffer)

TES is used to make buffer solutions. TES has a pKa value of 7.550 (at 25°C). TES can be used to make buffer solutions in the pH range 6.8-8.2[1].

  • CAS Number: 7365-44-8
  • MF: C6H15NO6S
  • MW: 229.25
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: ~225 °C (dec.)
  • Flash Point: N/A

Fexaramine

Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds. IC50 value:Target:in vitro: In vitro treatment of CDCA or fexaramine elevated the SHP transcript level and occupancy on secretin promoter [1]. Fexaramine significantly enhanced osteoblastic differentiation through the upregulation of Runx2 and enhanced extracellular signal-regulated kinase (ERK) and β-catenin signaling [2]. By mimicking this tissue-selective effect, the gut-restricted FXR agonist fexaramine (Fex) robustly induces enteric fibroblast growth factor 15 (FGF15), leading to alterations in BA composition, but does so without activating FXR target genes in the liver [3].

  • CAS Number: 574013-66-4
  • MF: C32H36N2O3
  • MW: 496.64000
  • Catalog: FXR
  • Density: 1.158g/cm3
  • Boiling Point: 677.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 363.7ºC

Potassium 7-hydroxy-1-naphthalenesulfonate

7-Hydroxy-1-naphthalenesulfonate (potassium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 30252-40-5
  • MF: C10H7KO4S
  • MW: 262.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

QUIN 2, Tetrapotassium Salt

QUIN 2, Tetrapotassium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 73630-23-6
  • MF: C26H23K4N3O10
  • MW: 693.86800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 831.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 456.7ºC

5b-Cholestane

5β-Cholestane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 481-20-9
  • MF: C27H48
  • MW: 372.670
  • Catalog: 5-HT Receptor
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 440.9±12.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.3±13.1 °C

Dimethyl (3-ethyl-3-methylpentyl)malonate

Tryptone is a common component of biological media. Tryptone is the polypeptone derived from the protein hydrolysis of animal tissue (pancreas) and digested by pancreatic enzymes. The main components of Tryptone were the digestion of casein by trypsin, including the peptones, small peptides and amino acids generated from the hydrolysis of casein. Tryptone provides nutrients needed for bacterial growth, especially nitrogen and carbon sources.

  • CAS Number: 73049-73-7
  • MF: C13H24O4
  • MW: 244.327
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 253.0±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 107.5±16.9 °C

Methyl Gerfelin

Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA). Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class[1][2].

  • CAS Number: 700870-56-0
  • MF: C16H16O6
  • MW: 304.29500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess ROS generation within human neuronal-glial (HNG) cells in primary co-culture[1]

  • CAS Number: 127770-45-0
  • MF: C25H14Cl2O9
  • MW: 529.279
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 743.3±60.0 °C at 760 mmHg
  • Melting Point: 210ºC (dec.)(lit.)
  • Flash Point: 403.3±32.9 °C

N6-Methyladenosine

N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes.

  • CAS Number: 1867-73-8
  • MF: C11H15N5O4
  • MW: 281.26800
  • Catalog: Others
  • Density: 1.85g/cm3
  • Boiling Point: 649.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 346.3ºC