Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Geneticin

G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

  • CAS Number: 108321-42-2
  • MF: C20H44N4O18S2
  • MW: 692.709
  • Catalog: Bacterial
  • Density: N/A
  • Boiling Point: 1012.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 565.9ºC

fmoc-d-thr-oh

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-threonine is a threonine derivative[1].

  • CAS Number: 157355-81-2
  • MF: C19H19NO5
  • MW: 341.358
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 596.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 314.6±30.1 °C

Bevemipretide

Bevemipretide is a biodegradable silica hydrogel composite. Bevemipretide can be used for ocular indication[1].

  • CAS Number: 2356106-71-1
  • MF: C31H45N9O4
  • MW: 607.75
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Angiotensin I/II (1-5)

Angiotensin I/II 1-5 is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

  • CAS Number: 58442-64-1
  • MF: C30H48N8O9
  • MW: 664.750
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Asp(OBzl)-OH

Z-Asp(OBzl)-OH is an aspartic acid derivative[1].

  • CAS Number: 3479-47-8
  • MF: C19H19NO6
  • MW: 357.357
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 587.4±50.0 °C at 760 mmHg
  • Melting Point: 105-107ºC
  • Flash Point: 309.1±30.1 °C

1-Methyladenine

1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.

  • CAS Number: 5142-22-3
  • MF: C6H7N5
  • MW: 149.15300
  • Catalog: Others
  • Density: 1.6 g/cm3
  • Boiling Point: 240.1ºC at 760 mmHg
  • Melting Point: > 300ºC
  • Flash Point: 99ºC

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

  • CAS Number: 97337-37-6
  • MF: C11H12ClN3O3
  • MW: 269.68428
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clove oil

Clove oil is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 8000-34-8
  • MF: C7H12ClN3O2
  • MW: 205.642
  • Catalog: Others
  • Density: 1.05 g/mL at 25 °C
  • Boiling Point: 251 °C(lit.)
  • Melting Point: N/A
  • Flash Point: >230 °F

Anthracene-9-carboxylic acid-d9

Anthracene-9-carboxylic acid-d9 is the deuterium labeled Anthracene-9-carboxylic acid[1]. Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[2].

  • CAS Number: 1219803-78-7
  • MF: C15H10O2
  • MW: 222.239
  • Catalog: Chloride Channel
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 467.5±14.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 206.1±14.8 °C

Ternidazole hydrochloride

Ternidazole hydrochloride is a hydroxymetabolite of nitroimidazole, has antiprotozoic properties[1][2].

  • CAS Number: 70028-95-4
  • MF: C7H12ClN3O3
  • MW: 221.641
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 419.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.8ºC

Cucurbit[7]uril

Cucurbit[7]uril is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 259886-50-5
  • MF: C42H42N28O14
  • MW: 1162.96000
  • Catalog: Others
  • Density: 2.69
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3’-Azido-3’-deoxy-N6-methyladenosine

3’-Azido-3’-deoxy-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 889126-08-3
  • MF:
  • MW:
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Thr(tBu)-OH

Fmoc-Thr(tBu)-OH is a threonine derivative[1].

  • CAS Number: 71989-35-0
  • MF: C23H27NO5
  • MW: 397.464
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 581.7±50.0 °C at 760 mmHg
  • Melting Point: 131-134 °C
  • Flash Point: 305.6±30.1 °C

LIMK-IN-22j

LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1].

  • CAS Number: 1116571-01-7
  • MF: C20H21BrN8
  • MW: 453.34
  • Catalog: LIM Kinase (LIMK)
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MAOS

MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium[1].

  • CAS Number: 82692-97-5
  • MF: C13H20NNaO4S
  • MW: 309.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Boc-D-methionine

Boc-D-Met-OH is a Methionine (HY-13694) derivative[1].

  • CAS Number: 5241-66-7
  • MF: C10H19NO4S
  • MW: 249.327
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 415.5±40.0 °C at 760 mmHg
  • Melting Point: 47-50ºC
  • Flash Point: 205.1±27.3 °C

1,1-Dioxothiolan-d8

1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan[1].

  • CAS Number: 51219-88-6
  • MF: C4D8O2S
  • MW: 128.21900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 283-285ºC
  • Melting Point: 25-27ºC
  • Flash Point: 177ºC

(-)-Terpinen-4-ol

(-)-Terpinen-4-ol can be extracted from Bark Beetle Polygraphus poligraphus[1].

  • CAS Number: 20126-76-5
  • MF: C10H18O
  • MW: 154.25
  • Catalog: Others
  • Density: 0.933
  • Boiling Point: 212ºC
  • Melting Point: N/A
  • Flash Point: 90ºC

nalpha-fmoc-l-serine tert-butyl ester

Fmoc-Ser-OtBu is a serine derivative[1].

  • CAS Number: 110797-35-8
  • MF: C22H25NO5
  • MW: 383.43800
  • Catalog: Others
  • Density: 1.217g/cm3
  • Boiling Point: 588.356ºC at 760 mmHg
  • Melting Point: 127ºC
  • Flash Point: 309.627ºC

N-Demethyl Erythromycin A

N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic[1].

  • CAS Number: 992-62-1
  • MF: C36H65NO13
  • MW: 719.90
  • Catalog: Others
  • Density: 1.21g/cm3
  • Boiling Point: 818.1ºC at 760mmHg
  • Melting Point: 142-144ºC
  • Flash Point: 448.6ºC

Boc-Asp(OBzl)-OSu

Boc-Asp(OBzl)-OSu is an aspartic acid derivative[1].

  • CAS Number: 13798-75-9
  • MF: C20H24N2O8
  • MW: 420.413
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 98-102ºC
  • Flash Point: N/A

Driselase

Driselase, a complex mixt. of wall-digesting enzymes, is a specific commercial fungal protoplasting enzyme preparation. Driselase is by far the most potent of the enzymes tested for polysaccharide digestion and greatly increases both tensile and indentation compliances, yet it does not induce wall creep, even after 6 h of digestion[1].

  • CAS Number: 85186-71-6
  • MF: C2H5N3O2
  • MW: 103.080001831055
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ASGPR ligand-1

ASGPR ligand-1 is an asialoglycoprotein receptor (ASGPR) ligand compound. ASGPR ligand-1 can be used for kinds of diseases research[1].

  • CAS Number: 1426160-58-8
  • MF: C61H110N10O27
  • MW: 1415.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methylcrotonylglycine

3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.

  • CAS Number: 33008-07-0
  • MF: C7H11NO3
  • MW: 157.16700
  • Catalog: Others
  • Density: 1.138g/cm3
  • Boiling Point: 394.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 192.6ºC

4-(3-Hydroxyprop-1-en-1-yl)phenol

p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. p-Coumaryl alcohol has inhibitory effect during the autoxidation of methyl linoleate[1][2].

  • CAS Number: 3690-05-9
  • MF: C9H10O2
  • MW: 150.17
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 323.5±22.0 °C at 760 mmHg
  • Melting Point: 124°C(lit.)
  • Flash Point: 162.7±16.9 °C

PF 05089771

PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.

  • CAS Number: 1235403-62-9
  • MF: C18H12Cl2FN5O3S2
  • MW: 500.35400
  • Catalog: Sodium Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CycloMusalenone

Cyclomusalenone is a natural product, that can be isolated from Muse sapientum[1].

  • CAS Number: 30452-60-9
  • MF: C30H48O
  • MW: 424.70
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 505.8±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.2±16.5 °C

Drp1-IN-1

Drp1-IN-1 (comp A-7) is a dynamin-1-like protein (Drp1) inhibitor, with an IC50 of 0.91 μM[1].

  • CAS Number: 2247733-08-8
  • MF: C22H24N8OS
  • MW: 448.54
  • Catalog: Dynamin
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SN 2

SN 2 is a novel and potent activator of TRPML3 ion channel with EC50 of 1.8±0.13 μM.

  • CAS Number: 823218-99-1
  • MF: C17H21NO
  • MW: 255.355
  • Catalog: TRP Channel
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 370.8±52.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 144.5±23.2 °C

beta1,3-Galactosyltransferase

beta1,3-Galactosyltransferase (CgtB) acts on N-glycan substrates. beta1,3-Galactosyltransferase catalyzes the formation of type 1 chains on oligosaccharide, glycopeptide, and glycoprotein substrates, including itself[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A