Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

TIBI

TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM). TIBI enhances the thermostability of the enzyme Rio1[1].

  • CAS Number: 1196457-06-3
  • MF: C7H2I4N2
  • MW: 621.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clomazone

Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco[1].

  • CAS Number: 81777-89-1
  • MF: C12H14ClNO2
  • MW: 239.698
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 317.6±44.0 °C at 760 mmHg
  • Melting Point: 25°C
  • Flash Point: 145.9±28.4 °C

Sphingosylphosphorylcholine-d9

Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine.

  • CAS Number: 2315262-28-1
  • MF: C23H40D9N2O5P
  • MW: 473.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

β-alanineethylester HCl

Ethyl 3-aminopropionate hydrochloride is an alanine derivative[1].

  • CAS Number: 4244-84-2
  • MF: C5H12ClNO2
  • MW: 153.607
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 167.8ºC at 760 mmHg
  • Melting Point: 67-70 °C(lit.)
  • Flash Point: N/A

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-beta-D-arabinopentofuranoside

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-beta-D-arabinopentofuranoside is an araboside analogue.

  • CAS Number: 197647-15-7
  • MF: C20H19FO5S
  • MW: 390.43
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hythiemoside A

Hythiemoside A is found in Sigesbeckia orientalis L[1].

  • CAS Number: 853267-91-1
  • MF: C28H46O9
  • MW: 526.66
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 681.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.0±25.0 °C

Galbelgin

(-)-Galbelgin is a lignan diastereoisomer. (-)-Galbelgin can be isolated from Piper kadsura[1].

  • CAS Number: 10569-12-7
  • MF: C22H28O5
  • MW: 372.45
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 479.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.4±28.6 °C

DTNB

DTNB(Ellman’s Reag) is a chemical used to quantify the number or concentration of thiol groups in a sample; can be used for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood.

  • CAS Number: 69-78-3
  • MF: C14H8N2O8S2
  • MW: 396.352
  • Catalog: Biochemical Assay Reagents
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 671.9±55.0 °C at 760 mmHg
  • Melting Point: 240-245 °C (dec.)(lit.)
  • Flash Point: 360.1±31.5 °C

Sodium 1-pyrenesulfonate

1-Pyrenesulfonic acid sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 59323-54-5
  • MF: C16H9NaO3S
  • MW: 304.296
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 233-236ºC(lit.)
  • Flash Point: N/A

N6,N6-dimethyladenine

6-(Dimethylamino)purine is a dual inhibitor of protein kinase and CDK[1][2].

  • CAS Number: 938-55-6
  • MF: C7H9N5
  • MW: 163.180
  • Catalog: CDK
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 427.4±25.0 °C at 760 mmHg
  • Melting Point: 259-262 °C(lit.)
  • Flash Point: 212.3±23.2 °C

L-SERINE BETA-NAPHTHYLAMIDE

L-Serine β-naphthylamide is a serine derivative[1].

  • CAS Number: 888-74-4
  • MF: C13H14N2O2
  • MW: 230.26200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

fluroxypyr-meptyl

Fluroxypyr-meptyl (Fluroxypyr-1-methylheptyl ester), a synthetical phytohormone, is used as herbicide agent[1][2].

  • CAS Number: 81406-37-3
  • MF: C15H21Cl2FN2O3
  • MW: 367.243
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 431.9±40.0 °C at 760 mmHg
  • Melting Point: 56-57ºC
  • Flash Point: 215.0±27.3 °C

Ganoderenic acid F

Ganoderenic acid F (compound 17) is a triterpenoid that can be found in ganoderma lucidum[1].

  • CAS Number: 120462-47-7
  • MF: C30H38O7
  • MW: 510.62
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 687.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 383.6±28.0 °C

MBN 305A

DODMA, a cationic lipid, is used for the preparation of liposomes. DOTMA is an effective gene transfection agent in vitro and in vivo.

  • CAS Number: 104162-47-2
  • MF: C41H81NO2
  • MW: 620.09
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 649.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 195.7±18.5 °C

Dantrolene Sodium

Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.

  • CAS Number: 14663-23-1
  • MF: C14H9N4NaO5
  • MW: 336.235
  • Catalog: Calcium Channel
  • Density: N/A
  • Boiling Point: 85°C 4mm
  • Melting Point: N/A
  • Flash Point: 283.1ºC

Boeravinone A

Boeravinone A is found in Boerhavia diffusa L[1].

  • CAS Number: 114567-33-8
  • MF: C18H14O6
  • MW: 326.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Heparin lithium salt

Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII).

  • CAS Number: 9045-22-1
  • MF: (C14H25NO20S3)n.xLi
  • MW: 148.159
  • Catalog: Autophagy
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 265.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.5±9.6 °C

Flumorph

Flumorph(SYP-L190) is a carboxylic acid amide (CAA) fungicide.IC50 value:Target: Fungicide agentFlumorph did not inhibit the synthesis of cell wall materials, but disturbed the polar deposition of newly synthesized cell wall materials during cystospore germination and hyphal growth. In flumorph-treated hyphae, the most characteristic change was the development of periodic swelling ("beaded" morphology) and the disruption of tip growth. Upon removing flumorph, normal tip growth and organized F-actin were observed again [1]. Flumorph had induced systemic genotoxicity in mammals as it caused DNA damage in all tested vital organs, especially in brain and spleen [2].

  • CAS Number: 211867-47-9
  • MF: C21H22FNO4
  • MW: 371.40200
  • Catalog: Fungal
  • Density: 1.208g/cm3
  • Boiling Point: 556.3ºC at 760mmHg
  • Melting Point: 122-125 °C
  • Flash Point: 290.3ºC

Fast Black K salt

Fast Black K Salt, a diazonium reagent, is a versatile thin-layer chromatographic visualisation reagent that can be used for the differentiation of aliphatic amines[1].

  • CAS Number: 64071-86-9
  • MF: C28H24Cl4N10O8Zn
  • MW: 835.773
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 150ºC (dec.)(lit.)
  • Flash Point: N/A

Biotin sulfone

Biotin sulfone is first isolated as a natural metabolite of biotin.

  • CAS Number: 40720-05-6
  • MF: C10H16N2O5S
  • MW: 276.30900
  • Catalog: Others
  • Density: 1.382g/cm3
  • Boiling Point: 706.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 381.2ºC

PONCEAU 3R

Ponceau 3R is an azo dye and can be used as a food colorant[1].

  • CAS Number: 3564-09-8
  • MF: C19H16N2Na2O7S2
  • MW: 494.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Neotriptonoterpene

Neotriptonoterpene, a compound isolated from T. regelii, shows weak cytotoxic activity against A2780, HepG2 and MCF-7 cells with IC50 values of 65.80, 35.45 and 64.80 µM respectively[1].

  • CAS Number: 117456-86-7
  • MF: C21H30O3
  • MW: 330.461
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 481.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 164.8±22.2 °C

Platycodigenin

Platicodigenin isolated from platycodon grandiflorum.

  • CAS Number: 22327-82-8
  • MF: C30H48O7
  • MW: 520.698
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 675.5±55.0 °C at 760 mmHg
  • Melting Point: 242-243 °C
  • Flash Point: 376.3±28.0 °C

Hirudonucleodisulfide B

Hirudonucleodisulfide B is a heterocyclic compound that can be found in Whitmania pigra. Hirudonucleodisulfide B shows moderately anti-anoxic activity[1].

  • CAS Number: 1072789-38-8
  • MF: C11H10N4O4S2
  • MW: 326.35
  • Catalog: Others
  • Density: 2.03±0.1 g/cm3(Predicted)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Lys(Mca)-OH

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysine is a lysine derivative[1].

  • CAS Number: 386213-32-7
  • MF: C33H32N2O8
  • MW: 584.61600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Chlorobenzoic acid-d4

3-Chlorobenzoic acid-d4 is the deuterium labeled 3-Chlorobenzoic acid-d4[1].

  • CAS Number: 2098655-72-0
  • MF: C7HD4ClO2
  • MW: 160.59
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

cis-Clopidogrel-MP Derivative

cis-Clopidogrel-MP Derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite[1]. Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor[2].

  • CAS Number: 1122047-98-6
  • MF: C25H26ClNO6S
  • MW: 503.99500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

9-Methymyrrhone

9-Methoxymyrrhone is a natural sesquiterpene that could be found in Myrrh[1].

  • CAS Number: 1809980-22-0
  • MF: C16H18O3
  • MW: 258.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 412.7±45.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

dethiobiotin

D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation[1].

  • CAS Number: 533-48-2
  • MF: C10H18N2O3
  • MW: 214.262
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 476.4±18.0 °C at 760 mmHg
  • Melting Point: 156-158 °C
  • Flash Point: 241.9±21.2 °C

3'-F-3'-dA(Bz)-2'-Phosphoramidite

3'-F-3'-dA(Bz)-2'-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

  • CAS Number: 2127174-09-6
  • MF: C47H51FN7O7P
  • MW: 875.92
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A