Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

PKH 26

PKH 26 is a lipophilic membrane dye and widely used to determine cell proliferation in heterogeneous cells by flow cytometry. It is a red‐fluorescent dye (Ex/Em=551/567nm)[1][2].

  • CAS Number: 154214-55-8
  • MF: C59H97IN2
  • MW: 961.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7,8-dihydroxy

7,8,3',4'-Tetrahydroxyflavanone is a flavonoid can be extracted from Acacia confusa[1].

  • CAS Number: 489-73-6
  • MF: C15H12O6
  • MW: 288.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine-d31

1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine-d31 is deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine.

  • CAS Number: 69285-95-6
  • MF: C40H49D31NO8P
  • MW: 765.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Chloro-4-(4-(pyrimidin-2-yl)piperazin-1-yl)quinoline

WAY-639418 is an active molecule for the study of amyloid diseases and synucleinopathies.

  • CAS Number: 643042-43-7
  • MF: C17H16ClN5
  • MW: 325.8
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Cyclohexylalanine

(R)-2-amino-3-cyclohexylpropanoic acid is an alanine derivative[1].

  • CAS Number: 58717-02-5
  • MF: C9H17NO2
  • MW: 171.237
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 307.1±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 139.6±23.2 °C

Styraxlignolide F

Styraxlignolide F is a natural compoundisolated from Styrax japonica.

  • CAS Number: 823214-06-8
  • MF: C27H34O11
  • MW: 534.552
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 756.4±60.0 °C at 760 mmHg
  • Melting Point: 128-130 °C
  • Flash Point: 250.1±26.4 °C

(D-Ser6,AzaGly10)-LHRH acetate salt

(D-Ser6,Azagly10)-LHRH is a biologically active peptide.

  • CAS Number: 65807-03-6
  • MF: C55H76N18O14
  • MW: 1213.30000
  • Catalog: Others
  • Density: 1.57
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pseudoginsenoside F11

Pseudoginsenoside-F11 (PF11), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. IC50 value: Inhibition of diprenorphine binding with an IC50 of 6.1 μM Target:In vitro: Biochemical experiments revealed that PF11 could inhibit diprenorphine (DIP) binding with an IC50 of 6.1 μM and reduced the binding potency of morphine in Chinese hamster ovary (CHO)-μ cells [2].In vivo: One in vivo model of cisplatin-induced acute renal failure was performed. The results showed that pretreatment with Pseudoginsenoside F11 reduced cisplatin-elevated blood urea nitrogen and creatinine levels, as well as ameliorated the histophathological damage [1]. We tested the effects of Pseudoginsenoside F11 on morphine-induced development of behavioral sensitization and alterations in glutamate levels in the medial prefrontal cortex (mPFC) in freely moving mice by using in vivo microdialysis. As the results shown, Pseudoginsenoside F11 antagonized the development of behavioral sensitization and decrease of glutamate in the mPFC induced by morphine [3].

  • CAS Number: 69884-00-0
  • MF: C42H72O14
  • MW: 801.013
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 885.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 489.2±34.3 °C

Galβ(1-3)GalNAc-β-pNP

Galβ(1-3)GalNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 59837-15-9
  • MF: C20H28N2O13
  • MW: 504.44200
  • Catalog: Others
  • Density: 1.62g/cm3
  • Boiling Point: 878.994ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 485.398ºC

Fmoc-Lys(5-FITC)-OH

Fmoc-Lys(5-FITC)-OH is a building block for in-sequence Lys labeling by FITC. FITC can be used to label peptides or proteins[1].

  • CAS Number: 1095493-05-2
  • MF: C42H35N3O9S
  • MW: 757.81
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Xylotetraose

Xylotetraose is a hydrolysis product of Xylan[1]. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose[2]. Xylotetraose can be used for enzyme biochemical analysis[1][3][4].

  • CAS Number: 22416-58-6
  • MF: C20H34O17
  • MW: 546.47400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate

Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 70255-70-8
  • MF: C12H15N5O6
  • MW: 325.28
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Complanatin I

Complanatin I is a natural product that can be isolated from Astragalus complanatus[1].

  • CAS Number: 138505-45-0
  • MF: C43H52O20
  • MW: 888.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

aglaine c

Aglain C is isolated from A. ponapensis. Aglain C enhances the NF-kB inhibitory activity[1].

  • CAS Number: 177468-85-8
  • MF: C36H42N2O8
  • MW: 630.73
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 839.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 461.8±34.3 °C

Cyhalofop-butyl

Cyhalofop-butyl is a post-emergence herbicide. Cyhalofop-butyl inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis[1].

  • CAS Number: 122008-85-9
  • MF: C20H20FNO4
  • MW: 357.375
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 449.1±45.0 °C at 760 mmHg
  • Melting Point: 49.5ºC
  • Flash Point: 225.4±28.7 °C

Isorhamnetin 3-glucoside-7-rhamnoside

Isorhamnetin 3-glucoside-7-rhamnoside (Luteoside) is a flavonoid that can be isolated from the aerial parts of B. tripartita[1].

  • CAS Number: 17331-71-4
  • MF: C25H48O4
  • MW: 412.646
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 525.2±30.0 °C at 760 mmHg
  • Melting Point: 222-224 °C
  • Flash Point: 161.9±18.1 °C

Dihydrobupropion-d9

Dihydrobupropion-d9 is the deuterium labeled Dihydrobupropion[1].

  • CAS Number: 1215071-07-0
  • MF: C13H11ClD9NO
  • MW: 250.81200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-DL-Asp-OH

Glycyl-DL-aspartic acid (Gly-DL-Asp) is an aspartate derivative that can be used for amino acids synthesis[1].

  • CAS Number: 79731-35-4
  • MF: C6H10N2O5
  • MW: 190.15400
  • Catalog: Others
  • Density: 1.499 g/cm3
  • Boiling Point: 468.7ºC at 760 mmHg
  • Melting Point: 199-202℃
  • Flash Point: 237.3ºC

(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE

Methyl vernolate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 2733-91-7
  • MF: C19H34O3
  • MW: 310.47
  • Catalog: Others
  • Density: 0.937g/cm3
  • Boiling Point: 391.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 150.9ºC

MFI8

MFI8 is a small molecule inhibitor of mitochondrial fusion[1].

  • CAS Number: 694488-83-0
  • MF: C16H18ClNO
  • MW: 275.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Bis(3-indolylmethyl)indole

2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.

  • CAS Number: 138250-72-3
  • MF: C26H21N3
  • MW: 375.47
  • Catalog: Others
  • Density: 1.314g/cm3
  • Boiling Point: 682.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 306.6ºC

5’(R)-C-Methylcytidine

5’(R)-C-Methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

  • CAS Number: 72159-53-6
  • MF:
  • MW:
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Amino-PPHT

4-Amino-PPHT (Compound 9a) is a PPHT derivative that selectively binds to dopamine D-2 receptors with a Ki value of 6.8 nM[1].

  • CAS Number: 129298-03-9
  • MF: C21H28N2O
  • MW: 324.46000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Bromo(20,20,20-2H3)icosane

1-Bromoicosane-d3 is the deuterium labeled 1-Bromoicosane[1].

  • CAS Number: 202480-72-6
  • MF: C20H38BrD3
  • MW: 364.462
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 383.2±5.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.4±10.5 °C

thymus peptide C

Thymus peptide C is a hormonal drug, derived from the thymus glands of young calves and acts as a substitute for the physiological functions of the thymus.

  • CAS Number: 316791-23-8
  • MF: CH3
  • MW: 15.03
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Bromo-1,3-difluorobenzene-d3

2-Bromo-1,3-difluorobenzene-d3 is the deuterium labeled 2-Bromo-1,3-difluorobenzene[1].

  • CAS Number: 1219803-73-2
  • MF: C6H3BrF2
  • MW: 192.989
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 149.8±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 53.3±0.0 °C

Dalbergin

Dalbergin is a composition of the extract from the Dalbergia Sissoo Linn. knot wood. Dalbergin demonstrats notable antioxidant ability[1].

  • CAS Number: 482-83-7
  • MF: C16H12O4
  • MW: 268.264
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 489.0±45.0 °C at 760 mmHg
  • Melting Point: 210ºC
  • Flash Point: 187.5±22.2 °C

Ethyl L-threoninate hydrochloride (1:1)

(2S,3R)-Ethyl 2-amino-3-hydroxybutanoate hydrochloride is a threonine derivative[1].

  • CAS Number: 39994-70-2
  • MF: C6H14ClNO3
  • MW: 183.633
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 254ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 107.4ºC

4-Methylumbelliferyl 2-Sulfamino-2-deoxy-α-D-glucopyranoside Sodium Salt

4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH2. 4-MU-α-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches[1][2][3].

  • CAS Number: 460085-45-4
  • MF: C16H18NNaO10S
  • MW: 439.36959
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2,4,5-Tetrachloro-3,6-dimethoxybenzene

1,2,4,5-Tetrachloro-3,6-dimethoxybenzene is an active compound. 1,2,4,5-Tetrachloro-3,6-dimethoxybenzene can be used for the research of various biochemical studies[1].

  • CAS Number: 944-78-5
  • MF: C8H6Cl4O2
  • MW: 275.94400
  • Catalog: Others
  • Density: 1.489g/cm3
  • Boiling Point: 330.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 128.4ºC