rac-1-Stearoyl-3-chloropropanediol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l
Monomethyl kolavate is a Trypanosoma brucei GAPDH enzyme (TbGAPDH) inhibitor with theIC50 value of 2 µM[1].
Fmoc-D-Ser(tBu)-OH is a serine derivative[1].
Bik BH3 is a biological active peptide. (BH3 domain of BIK)
3’-O-Methyl-4-deoxy uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
10-Undecenoic acid was used as a starting reagent in the syntheses of Pheromone (11Z)-hexadecenal.
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].
Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM[1].
13,14-Dihydro-15-keto PGF2a is an endogenous metabolite present in Blood that can be used for the research of Pregnancy[1][2].
5-PT formic is a serotonin derivative that can be functionalized with various reporter groups via click chemistry to investigate protein serotonylation. 5-PT formic can be used in vivo to observe endogenous protein serotonylation[1].
1) Natural acacetin was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.[1]2) Acacetin significantly suppressed the photoreceptor collapse. [1]3) Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. [1]4) Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage. [1]5) Acacetin prolongs lifespan of significantly in the dose dependent manner. Acacetin(25 uM) had the greatest effect on longevity, extending mean lifespan significantly by 27.31% at 25 uM concentration
GSK962 is an inactive enantiomer of GSK963 and can be used to confirm on-target effects[1].
H-N-Me-Ala-OH is an alanine derivative[1].
Biacetyl dioxime is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations[1].
Chamigrenal is a natural product that can be extract from the fruits of Schisandra sphenanthera[1].
N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonine is a threonine derivative[1].
Ethyl vanillin acetate is acectate form of ethyl vanillin. Ethyl vanillin acetate is a flavorant used in chocolate or candy[1].
6-Methylpurine-β-D-(3-azido-3-deoxy)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Gomisin U is a lignan compound[1].
(S)-tert-butyl 1-hydroxy-3-phenylpropan-2-ylcarbamate is a phenylalanine derivative[1].
Z-Val-ONp is a valine derivative[1].
FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.
Nε-(2,4-Dinitrophenyl)-L-lysine Hydrochloride is a lysine derivative[1].
L-Methionine p-nitroanilide is a Methionine (HY-13694) derivative[1].
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
Lushanrubescensin H (Rabdoternin H) is an ent-Kaurane diterpenoid from Isodon ternifolius aboveground part[1].