Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2-Methoxy-3,5-dimethylpyrazine-d3

2-Methoxy-3,5-dimethylpyrazine-d3 is the deuterium labeled 2-Methoxy-3,5-dimethylpyrazine[1].

  • CAS Number: 1335402-04-4
  • MF: C7H7D3N2O
  • MW: 141.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-methoxytryptophol

5-Methoxytryptophol is a natural indole present in the pineal gland.

  • CAS Number: 712-09-4
  • MF: C11H13NO2
  • MW: 191.22600
  • Catalog: Others
  • Density: 1.224 g/cm3
  • Boiling Point: 393.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192ºC

Methyl (9E)-9-hexadecenoate

Methyl palmitelaidate is a monounsaturated Fatty Acid Methyl Esters.

  • CAS Number: 10030-74-7
  • MF: C17H32O2
  • MW: 268.435
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 394.2±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 92.5±20.4 °C

5-Hydroxy-7,8-dimethoxyflavanone

7-O-Methyldihydrowogonin is a flavonoid that can be isolated from Andrographis paniculata[1].

  • CAS Number: 113981-49-0
  • MF: C17H16O5
  • MW: 300.31
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 524.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.0±23.6 °C

N,N-Dimethylglycine

N-Methylsarcosine is an amino acid building block for protein, found in a small amount in the body.

  • CAS Number: 1118-68-9
  • MF: C4H9NO2
  • MW: 103.120
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 175.2±23.0 °C at 760 mmHg
  • Melting Point: 178-182 °C(lit.)
  • Flash Point: 59.8±22.6 °C

[1-Bromo(2,2,2-2H3)ethyl]benzene

(1-Bromoethyl)benzene-d3 is the deuterium labeled (1-Bromoethyl)benzene[1].

  • CAS Number: 23088-42-8
  • MF: C8H6BrD3
  • MW: 188.079
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 203.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 81.7±0.0 °C

(-)-Corey lactone benzoate

(-)-Corey lactone benzoate is a building block in the chemical synthesis of corey aldehyde[1].

  • CAS Number: 39746-00-4
  • MF: C15H16O5
  • MW: 276.284
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 481.9±30.0 °C at 760 mmHg
  • Melting Point: 116-120 °C
  • Flash Point: 183.3±18.1 °C

BDP FL maleimide

BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy[1].

  • CAS Number: 773859-49-7
  • MF: C20H21BF2N4O3
  • MW: 414.214
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cynatratoside D

Cynatratoside D is a oligoglycoside isolated from the root of Cynanchum atratum Bunge (Asclepiadaceae)[1].

  • CAS Number: 97399-99-0
  • MF: C47H72O19
  • MW: 941.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2′-O-(2-Methoxyethyl)guanosine

2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2].

  • CAS Number: 473278-54-5
  • MF: C13H19N5O6
  • MW: 341.32000
  • Catalog: Others
  • Density: 1.811g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2’-β-C-Methyl-2-thiouridine

2’-β-C-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 1678507-60-2
  • MF: C10H14N2O5S
  • MW: 274.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3,6-Tri-O-galloylglucose

1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloyl-β-D-glucose) is a phenolic compound in Black Walnut Kernels[1].

  • CAS Number: 18483-17-5
  • MF: C27H24O18
  • MW: 636.46900
  • Catalog: Others
  • Density: 1.98g/cm3
  • Boiling Point: 1103.6ºC at 760mmHg
  • Melting Point: 167℃
  • Flash Point: 363ºC

DO3A tert-Butyl ester

DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.

  • CAS Number: 122555-91-3
  • MF: C26H50N4O6
  • MW: 514.698
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 561.6±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 293.4±30.1 °C

Fmoc-β-Lys(Boc)-OH

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid is a lysine derivative[1].

  • CAS Number: 219967-68-7
  • MF: C26H32N2O6
  • MW: 468.54200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SSI-4

SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11C, used as a ligand to in vivo small animal PET/CT imaging of SCD1[1].

  • CAS Number: 1875084-68-6
  • MF: C19H21ClN4O3
  • MW: 388.85
  • Catalog: Stearoyl-CoA Desaturase (SCD)
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Glu-Tyr-OH

Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support[1].

  • CAS Number: 988-75-0
  • MF: C22H24N2O8
  • MW: 444.43500
  • Catalog: Others
  • Density: 1.381g/cm3
  • Boiling Point: 815.3ºC at 760 mmHg
  • Melting Point: 185-187ºC
  • Flash Point: 446.9ºC

14-Deoxy-17-hydroxyandrographolide

14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate[1].

  • CAS Number: 869384-82-7
  • MF: C20H32O5
  • MW: 352.47
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 552.1±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.4±15.3 °C

Boc-D-Asp-OBzl

Boc-D-Asp-OBzl is an aspartic acid derivative[1].

  • CAS Number: 92828-64-3
  • MF: C16H21NO6
  • MW: 323.341
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 504.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.8±30.1 °C

H-Arg-Arg-Lys-Asp-Leu-His-Asp-Asp-Glu-Glu-Asp-Glu-Ala-Met-Ser-Ile-Thr-Ala-OH

Casein Kinase Substrates 3 is a substrate of casein kinase.

  • CAS Number: 154444-97-0
  • MF: C85H139N27O35S
  • MW: 2131.24000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,6-Dichlorobenzen-3,4,5-d3-amine

2,6-Dichlorobenzen-3,4,5-d3-amine is the deuterium labeled 2,6-Dichlorobenzen-amine[1].

  • CAS Number: 77435-48-4
  • MF: C6H2Cl2D3N
  • MW: 165.03500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glyasperin C

Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC50 of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis[1].

  • CAS Number: 142474-53-1
  • MF: C21H24O5
  • MW: 356.41200
  • Catalog: Others
  • Density: 1.243g/cm3
  • Boiling Point: 559.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 292ºC

Methoxyfenozide-d9

Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide[1]. Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively)[2].

  • CAS Number: 2469014-53-5
  • MF: C22H19D9N2O3
  • MW: 377.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ALLOTETRAHYDROCORTISOL

Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes[1][2].

  • CAS Number: 302-91-0
  • MF: C21H34O5
  • MW: 366.49200
  • Catalog: Others
  • Density: 1.253g/cm3
  • Boiling Point: 545.1ºC at 760mmHg
  • Melting Point: 244.5ºC
  • Flash Point: 297.6ºC

Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH

Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 911838-56-7
  • MF: C33H43N3O8
  • MW: 609.71000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

acid red 1

Azophloxine, also known as acid red 1 (AR1), is a member of synthetic red azo dye family[1].

  • CAS Number: 3734-67-6
  • MF: C18H13N3Na2O8S2
  • MW: 509.421
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

delta7-Avenasterol

Avenasterol is a natural sterol isolated from seed oils of Testouri and Jebali cultivars[1].

  • CAS Number: 23290-26-8
  • MF: C29H48O
  • MW: 412.69100
  • Catalog: Others
  • Density: 0.98±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HBX

DCAF is an electron-deficient azaacene and acts as an electron injection material for organic light-emitting diodes[1].

  • CAS Number: 40114-84-9
  • MF: C13H4N4O
  • MW: 232.20
  • Catalog: Others
  • Density: 1.55g/cm3
  • Boiling Point: 565ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.5ºC

IRE1α kinase-IN-7

IRE1α kinase-IN-7 (compound 4) is an IRE1α kinase inhibitor. IRE1α kinase-IN-7 can be used for research of endoplasmic reticulum stress-related diseases[1].

  • CAS Number: 1414938-22-9
  • MF: C28H25F3N6O
  • MW: 518.53
  • Catalog: IRE1
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Subtilisin (Compound proteinase)

Subtilisin Compound proteinase (Protamex) is a proteolytic enzyme. Subtilisin Compound proteinase has catalytic activity in anhydrous dimethyl formamide. Subtilisin Compound proteinase can be used as a catalyst for easy coupling between sugars and amino acids[1][2].

  • CAS Number: 9014-01-1
  • MF: C11H9N3O2.Na
  • MW: 238.19786
  • Catalog: Others
  • Density: 1.3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isopropyl catechol

3-Isopropylcatechol is a catechol produced by Rhodococcus erythropolis BD2[1].

  • CAS Number: 2138-48-9
  • MF: C9H12O2
  • MW: 152.190
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 265.3±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 125.7±16.4 °C