Z-Pro-Leu-Gly-OEt is a tripeptide[1].
Dihydro T-MAS-d6 is deuterium labeled Dihydro T-MAS.
3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids[1].
Prosaikogenin H is an intestinal metabolite of saikosaponin with a weak hemolytic activity[1].
D-Erythrose-1-13C is the 13C labeled D-Erythrose[1].
Hexachlorophene(Hexachlorofen) is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM; also is an inhibitor of Wnt/beta-catenin signaling.IC50 value: 4.61 ± 1.29 μM(EC50) [1]Target: KCNQ1 activatorin vitro: HCP potently increases the current amplitude of KCNQ1/KCNE1 expressed by stabilizing the channel in an open state with an EC(50) of 4.61 ± 1.29 μM. Further studies in cardiomyocytes showed that HCP significantly shortens the action potential duration at 1 μM. In addition, HCP is capable of rescuing the loss of function of the LQTs mutants caused by either impaired activation gating or phosphatidylinositol-4,5-bisphosphate (PIP2) binding affinity [1]. Hexachlorophene antagonized CRT that was stimulated by Wnt3a-conditioned medium by promoting the degradation of beta-catenin. hexachlorophene represses the expression of cyclin D1 [2]. Triclosan and hexachlorophene inhibited both ecFabI and saFabI. hexachlorophene prevented the formation of a stable FabI-NAD(P)(+)-drug ternary complex [3].
Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2[1].
Broussoflavonol F possess xanthine oxidase inhibitory activity[1].
Fmoc-(FmocHmb)Leu-OH is a leucine derivative[1].
Dendrotoxin K is a Kv1.1 channel blocker. Dendrotoxin K determines glutamate release in CA3 neurons in a time-dependent manner through the control of the presynaptic spike waveform[1].
Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site[1][2].
Diethylamine-d10 hydrobromide is the deuterium labeled Diethylamine hydrobromide[1].
Orthosphenic acid (compound 12) is a natural product isolated from the roots of Tripterygium wilfordii[1].
HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM[1].
Caftaric acid is a natural product.
5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca2+ specific chelators, Ca2+ buffers, and fluorescent Ca2+ indicators[1][2].
gamma-Glutamylarginine, an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng[1].
Ingenol-5,20-acetonide is an intermediate from ingenol for synthesis of ingenoids; improved stability compared to ingenol.
Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, drug, compounds synthesis[1].
2-Methoxyphenyl benzoate is an active compound[1].
2-Fluorobenzoic acid-d4 is the deuterium labeled 2-Fluorobenzoic acid[1].
Ethyl petroselaidate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
4-Methoxybenzaldehyde-d1 is the deuterium labeled 4-Methoxybenzaldehyde[1]. 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking[2].
Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
CER7-2’R,6R-d9 is deuterium labeled CER7-2’R,6R.
DEAC, SE (7-Diethylaminocoumarin-3-carboxylic acid, SE) is an excellent blue fluorescent building block for labeling amine-containing biomolecules.
Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides[1].
Chitotriose trihydrochloride is an orally active chitooligosaccharide with antioxidant activities. Chitotriose trihydrochloride inhibits hydroxylation of benzoate to salicylate by H2O2 in the presence of Cu2+ (IC50 value of 80 μM)[1].
Benzobicyclon is a pro-herbicide, which acts as an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) in plant, and leads to bleaching and death[1].