N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d12 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)[1].
Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1].
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research[1].
Boc-Asp-OMe is an aspartic acid derivative[1].
Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2].
Tetrapeptide-4 is a peptide ingredient commonly used in skin care products to reduce wrinkles, strengthen collagen, elastin and fibronectin, and possess powerful anti-aging properties[1].
Metaxalone-d6 is deuterium labeled Metaxalone.
Pep-1 (uncapped) is a cell-penetrating peptide.
Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity[1].
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].
3,5,7-Trimethoxyflavone, a flavonoid compound, can inhibit the TNF-α-induced high expression and secretion of MMP-1 by cells. 3,5,7-Trimethoxyflavone can be used to ameliorate skin damage[1].
Undecylamine-d23 is the deuterium labeled Undecylamine[1].
S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters[1].
Trometamol is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol is an effective amine compound for pH control in the physiological range[1].
Lemalesomab (IMMU-MN3) is a mouse IgG1 Anti-NCA-90 monoclonal antibody and a Fab'fragment. Lemalesomab can be used for the research of inflammation, infectious lesions and infection imaging[1].
Dibenzyl hydrazodicarboxylate (Dibenzyl hydrazine-1,2-dicarboxylate) is a protein cross-linking agent.
Pseudobufarenogin is a natural compound extracted from toad species with unknown details.
(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid is a valine derivative[1].
Monomethyl auristatin E intermediate-12 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress[1].
N-(3-Mercapto-2-methylpropanoyl)glycine-d5 is the deuterium labeled N-(3-Mercapto-2-methylpropanoyl)glycine[1].
(±)-Sigmoidin A is an active compound. (±)-Sigmoidin A can be used for the research of various biochemical [1].
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine[1].
Momordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity[1].
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations[1].
SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1].
Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation[1].
Isovalerylshikonin (IVS) is a shikonin pigment is identified in the root epidermis of Echium italicum L[1].
Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate is an alanine derivative[1].