Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

massonianoside b

Massonianoside B is an antioxidant, which can be isolated from Cedrus deodara pine needle. Massonianoside B exhibits radicals scavenging capacities, and restores CCL4-impaired activity of antioxidant enzymes[1].

  • CAS Number: 188300-19-8
  • MF: C25H32O10
  • MW: 492.52
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 708.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 382.6±32.9 °C

Hexyl nicotinoate

Hexyl nicotinate, a nicotinic acid ester with vasodilatory effect. Hexyl nicotinate improves blood circulation, usually serves as an active ingredient in topical preparations, such as creams and lotions[1].

  • CAS Number: 23597-82-2
  • MF: C12H17NO2
  • MW: 207.26900
  • Catalog: Others
  • Density: 1,02 g/cm3
  • Boiling Point: 140°C
  • Melting Point: N/A
  • Flash Point: 140ºC

Linderene acetate

Linderene acetate, isolated from the root of Lindera strychnifolia, is a prolyl endopeptidase inhibitor[1].

  • CAS Number: 26146-28-1
  • MF: C17H20O3
  • MW: 272.33900
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Metaxalone

Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles.Target: OthersMetaxalone is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is considered to be a moderately strong muscle relaxant, with relatively low incidence of side effects.

  • CAS Number: 1665-48-1
  • MF: C12H15NO3
  • MW: 221.252
  • Catalog: Neurological Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 453.6±14.0 °C at 760 mmHg
  • Melting Point: 121-123ºC
  • Flash Point: 228.2±20.1 °C

Dehydroevodiamine hydrochloride

Dehydroevodiamine hydrochloride is isolated from the leaves of Evodia rutaecarpa[1].

  • CAS Number: 111664-82-5
  • MF: C19H16ClN3O
  • MW: 337.803
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

OSW-1

OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of osterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human cancer lines.

  • CAS Number: 145075-81-6
  • MF: C47H68O15
  • MW: 873.03400
  • Catalog: Others
  • Density: 1.31 g/cm3
  • Boiling Point: 932.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 267ºC

Fmoc-Val-Ser(psi(Me,Me)pro)-OH

Fmoc-Val-Ser(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 186023-49-4
  • MF: C26H30N2O6
  • MW: 466.52600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pregnane-3,11,20-trione,21-(acetyloxy)-17-hydroxy-, (5b)- (9CI)

5β-Dihydrocortisone acetate can be used for the synthesis of tetrahydrocortisone 3-glucuronide[1].

  • CAS Number: 1499-59-8
  • MF: C23H32O6
  • MW: 404.49700
  • Catalog: Others
  • Density: 1.224g/cm3
  • Boiling Point: 556.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 187.9ºC

Cyanine7 DBCO

Cyanine7 DBCO is a water-soluble NIR fluorescent dye with cycloalkyne moiety[1].

  • CAS Number: 2692677-77-1
  • MF: C58H65F6N4O2P
  • MW: 995.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Caesalpine A

Caesalpine A, a cassane-type diterpene, is a natural product that could be isolated from the seeds of Caesalpinia minax[1].

  • CAS Number: 1616757-59-5
  • MF: C23H32O7
  • MW: 420.496
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 515.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 265.8±30.1 °C

WAY-221060

WAY-221060-A is an active molecule.

  • CAS Number: 1351406-38-6
  • MF: C17H18N4O
  • MW: 294.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzyl cinnamate

Benzyl cinnamate, occurs in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, is used in heavy oriental perfumes and as a fixative[1].

  • CAS Number: 103-41-3
  • MF: C16H14O2
  • MW: 238.281
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 195-200 ºC (5 mmHg)
  • Melting Point: 34-37 °C(lit.)
  • Flash Point: 225.7±10.4 °C

Clitorin

Clitorin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, and has antioxidant activity[1][2].

  • CAS Number: 55804-74-5
  • MF: C33H40O19
  • MW: 740.66
  • Catalog: Others
  • Density: 1.74±0.1 g/cm3(Predicted)
  • Boiling Point: 1054.0±65.0 °C(Predicted)
  • Melting Point: 204-206 °C
  • Flash Point: N/A

(D-Phe7)-Somatostatin-14

(D-Phe7)-Somatostatin-14 is a biologically active peptide.

  • CAS Number: 64813-74-7
  • MF: C76H106N18O19S2
  • MW: 1639.894
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1980.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1151.3±34.3 °C

H-Ala-Lys-OH · HCl

(S)-6-Amino-2-((S)-2-aminopropanamido)hexanoic acid hydrochloride is a lysine derivative[1].

  • CAS Number: 68973-27-3
  • MF: C9H20ClN3O3
  • MW: 253.72600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Citromycetin

Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp[1].

  • CAS Number: 478-60-4
  • MF: C14H10O7
  • MW: 290.22500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-Fmoc-2-amino-5,5,5-trifluoropentanoic acid

N-Fmoc-5,5,5-trifluoro-L-norvaline is an amino acid derivative that can be used for compound synthesis[1].

  • CAS Number: 144207-41-0
  • MF: C20H18F3NO4
  • MW: 393.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gochnatiolide A

Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].

  • CAS Number: 87606-12-0
  • MF: C30H30O7
  • MW: 502.56
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Icaridin

Picaridin (Lcaridin) is a topical insect repellent[1].

  • CAS Number: 119515-38-7
  • MF: C12H23NO3
  • MW: 229.316
  • Catalog: Infection
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 330.9±15.0 °C at 760 mmHg
  • Melting Point: below -170ºC
  • Flash Point: 153.9±20.4 °C

Boc-Cha-OMe

Boc-Cha-OMe is an alanine derivative[1].

  • CAS Number: 98105-41-0
  • MF: C15H27NO4
  • MW: 285.37900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 47-49 ℃(lit.)
  • Flash Point: N/A

4',6-Diamidino-2-phenylindole dihydrochloride

DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.

  • CAS Number: 28718-90-3
  • MF: C16H17Cl2N5
  • MW: 350.246
  • Catalog: Dye Reagents
  • Density: 1.41g/cm3
  • Boiling Point: 545.4ºC at 760mmHg
  • Melting Point: >300°C (dec.)
  • Flash Point: 283.6ºC

Nikethamide

Nikethamide, one of the respiratory central stimulants, is used to treat respiratory failure in clinical practice.

  • CAS Number: 59-26-7
  • MF: C10H14N2O
  • MW: 178.231
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 298.0±0.0 °C at 760 mmHg
  • Melting Point: 23 °C(lit.)
  • Flash Point: 141.1±20.4 °C

Alpinone 3-acetate

3-Acetylpinobanksin-7-methyl ether is a natural product that can be isolated from propolis[1].

  • CAS Number: 139906-49-3
  • MF: C18H16O6
  • MW: 328.316
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Laurycolactone B

Laurycolactone B is a natural product from Eurycoma longifolia Jack[1].

  • CAS Number: 85643-77-2
  • MF: C18H20O5
  • MW: 316.34800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Monomethyl auristatin E intermediate-9

Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

  • CAS Number: 120205-58-5
  • MF: C22H35NO5
  • MW: 393.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3′,4′,5-Tetrachlorobiphenyl-3,4,6-d3

2,3′,4′,5-Tetrachlorobiphenyl-3,4,6-d3 is the deuterium labeled 2,3′,4′,5-Tetrachlorobiphenyl[1].

  • CAS Number: 1219794-77-0
  • MF: C12H3D3Cl4
  • MW: 295.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Ethyl-2-methoxyphenol-d5

4-Ethyl-2-methoxyphenol-d5 is the deuterium labeled 4-Ethyl-2-methoxyphenol[1].

  • CAS Number: 1219803-12-9
  • MF: C9H12O2
  • MW: 152.190
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 246.5±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 107.8±0.0 °C

Yadanzioside A

Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity[1].

  • CAS Number: 95258-15-4
  • MF: C32H44O16
  • MW: 684.68200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

14:0-14:0 PC-d27

14:0-14:0 PC-d27 is deuterium labeled 14:0-14:0 PC.

  • CAS Number: 185906-02-9
  • MF: C36H45D27NO8P
  • MW: 705.10
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A