Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves.
H-His(1-Me)-OMe is a histidine derivative that can be used for amino acid synthesis[1].
γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569)[1]
3',4',5',5,7-Pentamethoxyflavanone is a natural flavonoid compound found in Neoraptua magnifica var. magnifica[1].
Piperitol is a compound isolated from the Tibetan medicinal plant Lancea tibetica[1].
17α,20β-Dihydroxy-4-pregnen-3-one (17,20β-P) is a maturation-inducing steroid[1].
Kadsuphilin A can be extracted from Kadsura coccinea (Lem.) and has weak antiproliferative activity[1].
Z-Phe-OBzl is a phenylalanine derivative[1].
Aloin(Aloin-A; Barbaloin-A) is a natural antitumor anthraquinone glycoside with iron chelating and non-atherogenic activities.IC50 value:Target:in vitro: Aloin significantly inhibited HUVECs proliferation, migration and tube formation in vitro. suppressed activation of VEGF receptor (VEGFR) 2 and STAT3 phosphorylation in endothelial cells. In addition, the constitutively activated STAT3 protein, and the expression of STAT3-regulated antiapoptotic (Bcl-xL), proliferative (c-Myc), and angiogenic (VEGF) proteins were also down-regulated in response to AL in human SW620 cancer cells [1]. aloin exerted inhibition of cell proliferation, adhesion and invasion abilities of B16-F10 melanoma cells under non-cytotoxic concentrations. Furthermore, aloin induced melanoma cell differentiation through the enhancement of melanogenesis and transglutaminase activity [2].in vivo: Aloin substantially reduced tumor volumes and weight in vivo mouse xenografts, without obviously toxicity [1]. Aloin (10, 30 mg/kg bw) or vehicle was given by gavage to mice after each alcohol administration. Alcohol elevated the serum transaminases alanine aminotransferase, aspartate aminotransferase, total cholesterol and triglyceride levels which were significantly attenuated by the co-administration of aloin (p < 0.05) [3].
Fmoc-Met-OH is a Methionine (HY-13694) derivative[1].
H-L-Photo-Phe-OH is a phenylalanine derivative[1].
Tau-aggregation and neuroinflammation-IN-1 is a potent tau-aggregation and neuroinflammation inhibitor. Tau-aggregation and neuroinflammation-IN-1 exhibits remarkable inhibitory activities against AcPHF6 and full-length tau aggregation. Tau-aggregation and neuroinflammation-IN-1 has a low cytotoxicity and reduced NO release in LPS-stimulated BV2 cells. Tau-aggregation and neuroinflammation-IN-1 can reverse okadaic acid-induced memory impairment in rats[1].
BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor[1].
Eupteleasaponin I is a component of Euptelea polyandra, may has gastroprotective activity[1].
Phosphate dibasic-d2 (sodium) is the deuterium labeled Sodium phosphate dibasic[1].
MK196 (MK-196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.
Vitamin A is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal[1].
TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].
GW 610 (NSC 721648), an antitumor agent, shows potent and selective anticancer activity against lung, colon, and breast cancer cell lines[1][2][3].
WAY-329738 is an active molecule for research into amyloid diseases and synucleinopathies.
Celangulin is an insecticidal component isolated from Celastrus angulatus. Celangulin activates the calcium channel on the plasma membrane with increasing the intracellular Ca2+ after influx from the external. Celangulin activates the calcium channel in the ER[1].
H-Phe-Phe-Phe-Phe-OH is a tetrapeptide that can generate vertically aligned, highly ordered 3-D bionanostructures[1].
(Lys7)-Phalloidin is a biologically active peptide.
Ethyl 3-hydroxybutyrate is a fragrance found in wine and Tribolium castaneum[1][2].
Berninamycin D is a cyclic peptide fungal metabolite isolated from ermentation of Streptomyces bernensis[1].
Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens[1][2].
(Rac)-Baxdrostat is the inactive isomer of Baxdrostat (HY-132809), and can be used as an experimental control. Baxdrostat is a aldosterone synthase inhibitor[1].
Tricarbonyldichlororuthenium(II) dimer is a pharmacological donor of CO releasing. CO releases from Tricarbonyldichlororuthenium(II) dimer prevents gastric mucosal oxidative damage induced by ischemia/reperfusion (I/R) improving gastric blood flow (GBF), decreasing DNA oxidation and inflammatory response on systemic level[1].
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.
Fmoc-N-Me-Leu-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.