Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fmoc-Glu(Ome)-OH

Fmoc-Glu(OMe)-OH is a glutamic acid derivative[1].

  • CAS Number: 145038-50-2
  • MF: C21H21NO6
  • MW: 383.39500
  • Catalog: Others
  • Density: 1.296 g/cm3
  • Boiling Point: 625.332ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 331.989ºC

H-Phe-Gly-OH

Phe-Gly hydrate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 721-90-4
  • MF: C11H14N2O3
  • MW: 222.24000
  • Catalog: Others
  • Density: 1.259g/cm3
  • Boiling Point: 512.5ºC at 760 mmHg
  • Melting Point: -260ºC (dec.)
  • Flash Point: 263.7ºC

METHYL PENTADECANOATE-D29

Methyl pentadecanoate-d29 is the deuterium labeled Methyl pentadecanoate[1].

  • CAS Number: 68060-02-6
  • MF: C16H3D29O2
  • MW: 285.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,7-DIMETHYLGALANGIN

5-Hydroxy-3,7-dimethoxyflavone (compound 1) can be isolated from Kaempferia parviflora, but has no significant toxicity to malaria parasites, fungi, and bacteria[1].

  • CAS Number: 70786-48-0
  • MF: C17H14O5
  • MW: 298.29000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2H-1-Benzopyran-2-one, 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy

6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source[1].

  • CAS Number: 425370-70-3
  • MF: C16H20O6
  • MW: 308.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Terminal Deoxynucleotidyl Transferase

Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Phe-OH

Boc-D-Phe-OH is a phenylalanine derivative[1].

  • CAS Number: 18942-49-9
  • MF: C14H19NO4
  • MW: 265.305
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 426.6±38.0 °C at 760 mmHg
  • Melting Point: 85-88ºC
  • Flash Point: 211.8±26.8 °C

p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].

  • CAS Number: 77640-21-2
  • MF: C18H25NO12
  • MW: 447.39100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 233-236ºC dec.
  • Flash Point: N/A

Z-Glu-OtBu

Z-Glu-OtBu is a glutamic acid derivative[1].

  • CAS Number: 5891-45-2
  • MF: C17H23NO6
  • MW: 337.368
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 522.6±50.0 °C at 760 mmHg
  • Melting Point: 83 °C
  • Flash Point: 269.9±30.1 °C

Isocupressic acid

Isocupressic acid ((+)-Isocupressic acid) is an abortifacient compound[1].

  • CAS Number: 1909-91-7
  • MF: C20H32O3
  • MW: 320.466
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 454.2±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 242.6±23.3 °C

Volixibat

Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH)[1][2].

  • CAS Number: 1025216-57-2
  • MF: C38H51N3O12S2
  • MW: 805.954
  • Catalog: Metabolic Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Umirolimus

Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used drug-eluting stent (DES) applications[1].

  • CAS Number: 851536-75-9
  • MF: C55H87NO14
  • MW: 986.278
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 991.0±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 553.1±37.1 °C

Boc-Gln-Gly-Arg-AMC

Boc-Gln-Gly-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 113865-85-3
  • MF: C28H40N8O8
  • MW: 616.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Etidronic acid

Etidronic acid is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment.Target: OthersEtidronic Acid is a chelating agent and may be added to bind to or counter the effects of substances such as arsenic, iron, or other metal ions that can occur in the presence of some soaps. Etidronic acid also acts to retard oxidation of fatty acids. For clarification, a chelator, or chelating agent is a binding component added to many cosmetics, beauty products, and water softeners to form multiple bonds with a single metal ion and neutralize it.

  • CAS Number: 2809-21-4
  • MF: C2H8O7P2
  • MW: 206.028
  • Catalog: Others
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 578.8±60.0 °C at 760 mmHg
  • Melting Point: 198~199℃
  • Flash Point: 303.8±32.9 °C

leupeptin

Leupeptin Ac-LL is a protease inhibitor from actinomycetes. Leupeptin Ac-LL has antiplasmin activity[1].

  • CAS Number: 24365-47-7
  • MF: C20H38N6O4
  • MW: 426.55400
  • Catalog: Cancer
  • Density: 1.21g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Val-Phe-OH

L-Valyl-L-phenylalanine (Valylphenylalanine; H-VAL-PHE-OH) has been reported as biocompatible polymer.

  • CAS Number: 3918-92-1
  • MF: C14H20N2O3
  • MW: 264.32000
  • Catalog: Inflammation/Immunology
  • Density: 1.166g/cm3
  • Boiling Point: 493.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 252.1ºC

1,3-Bis[(2H5)phenyl]urea

1,3-Diphenylurea-d10 is the deuterium labeled 1,3-Diphenylurea[1].

  • CAS Number: 108009-46-7
  • MF: C13H2D10N2O
  • MW: 222.309
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 262.0±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 91.1±18.9 °C

(4,5,6,7-2H4)-1H-Benzotriazole

1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole[1].

  • CAS Number: 1185072-03-0
  • MF: C6HD4N3
  • MW: 123.149
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 359.2±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.7±12.2 °C

H-DL-Glu(OMe)-OH

H-DL-Glu(Ome)-OH is a glutamic acid derivative[1].

  • CAS Number: 14487-45-7
  • MF: C6H11NO4
  • MW: 161.15600
  • Catalog: Others
  • Density: 1.242g/cm3
  • Boiling Point: 316.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 145ºC

LEI110(LEI-110

LEI110 (LEI-110) is a potent Phospholipase A2 group XVI (PLA2G16) inhibitor with Ki of 20 nM, also has activity on HRASLS2, RARRES3 and iNAT (pIC50=6.8-7.6); reduces cellular arachidonic acid levels and oleic acid-induced lipolysis in human HepG2 cells; LEI110 is a selective pan-inhibitor of the HRASLS-family of thiol hydrolases (i.e. PLA2G16, HRASLS2, RARRES3 and iNAT).

  • CAS Number: 2313525-90-3
  • MF: C25H23F3N2O3
  • MW: 456.465
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Lys(Ac)5.8.12.16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) trifluoroacetate salt

(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) is a biologically active peptide.

  • CAS Number: 2022956-65-4
  • MF: C141H243N53O43S
  • MW: 3400.88
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12-Hydroxyisobakuchiol

12-Hydroxyisobakuchiol, meroterpene derivative, is a natural product. 12-Hydroxyisobakuchiol can be isolated from the leaves of Psoralea glandulosa[1].

  • CAS Number: 178765-55-4
  • MF: C18H24O2
  • MW: 272.38200
  • Catalog: Others
  • Density: 1.026±0.06 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Fluorobenzonitrile-d2

4-Fluorobenzonitrile-d2 is the deuterium labeled 4-Fluorobenzonitrile[1].

  • CAS Number: 83741-75-7
  • MF: C5H8D2O2
  • MW: 104.14400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MELPERONE

Melperone, a butyrophenone, is an antipsychotic drug used for sleep induction which is frequently prescribed in psychiatric setting[1]. Melperone has been used for a variety of indications, including the treatment of schizophrenia, but also for agitation in the elderly[2].

  • CAS Number: 3575-80-2
  • MF: C16H22FNO
  • MW: 263.35000
  • Catalog: Neurological Disease
  • Density: 1.046g/cm3
  • Boiling Point: 376.1ºC at 760mmHg
  • Melting Point: 78-82°C
  • Flash Point: 181.3ºC

4-(2H4)Pyridin(2H)ol

Pyridin-4-ol-d5 is the deuterium labeled Pyridin-4-ol[1].

  • CAS Number: 45503-33-1
  • MF: C5D5NO
  • MW: 100.130
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 380.6±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 182.3±20.4 °C

N-Pyrazinylcarbonylphenylalanine-d8

N-Pyrazinylcarbonylphenylalanine-d8 is the deuterium labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

  • CAS Number: 1331912-47-0
  • MF: C14H5D8N3O3
  • MW: 279.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-L-leucinol

Boc-Leucinol is a leucine derivative[1].

  • CAS Number: 82010-31-9
  • MF: C11H23NO3
  • MW: 217.305
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 319.3±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 146.9±23.2 °C

Abz-Gly-p-nitro-Phe-Pro-OH trifluoroacetate salt

Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths[1].

  • CAS Number: 67482-93-3
  • MF: C23H25N5O7
  • MW: 483.47
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 908.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 503.0±34.3 °C

2-(2H3)Methyl(2H6)butanoic acid

DL-2-Methylbutyric acid-d9 is the deuterium labeled DL-2-Methylbutyric acid[1].

  • CAS Number: 352431-44-8
  • MF: C5HD9O2
  • MW: 111.187
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 175.3±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 73.9±0.0 °C

2,6-Dibromo-4-cyanophenyl octanoate

Bromoxynil octanoate is an herbicide widely applied to maize, is potentially toxic to both animals and humans[1].

  • CAS Number: 1689-99-2
  • MF: C15H17Br2NO2
  • MW: 403.109
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 424.6±45.0 °C at 760 mmHg
  • Melting Point: 45-46°C
  • Flash Point: 210.6±28.7 °C