Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Condurango glycoside E3

Condurango glycoside E3 (Compound 5) is a pregnanate glycoside derived from the dry bark of Marsdenia cundurango[1].

  • CAS Number: 115784-10-6
  • MF: C66H98O26
  • MW: 1307.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AMG 487 S-enantiomer

AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.

  • CAS Number: 473720-30-8
  • MF: C32H28F3N5O4
  • MW: 603.591
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 750.0±70.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 407.4±35.7 °C

7-Prenyloxyaromadendrin

7-Prenyloxyaromadendrin is a flavonoid from Pterocaulon alopecuroides with antitumor activity. 7-Prenyloxyaromadendrin shows good antiproliferative activity in tumor cell lines[1][2].

  • CAS Number: 78876-50-3
  • MF: C20H20O6
  • MW: 356.37
  • Catalog: Others
  • Density: 1.343±0.06 g/cm3
  • Boiling Point: 624.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

4-Nitrosomorpholine

N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].

  • CAS Number: 59-89-2
  • MF: C4H8N2O2
  • MW: 116.118
  • Catalog: Autophagy
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 226.1±15.0 °C at 760 mmHg
  • Melting Point: 29ºC
  • Flash Point: 90.5±20.4 °C

seravschanin

Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056)-induced NO production in mouse peritoneal macrophages[1].

  • CAS Number: 77331-76-1
  • MF: C20H22O7
  • MW: 374.38
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 465.7±45.0 °C at 760 mmHg
  • Melting Point: 166-167℃ (ethanol )
  • Flash Point: 202.5±28.8 °C

7-Octyn-1-ol

7-Octyn-1-ol is the precursor to 7-octynoic acid. 7-Octyn-1-ol oxidation results in 7-octynoic acid[1].

  • CAS Number: 871-91-0
  • MF: C8H14O
  • MW: 126.196
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 191.5±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 116.3±14.9 °C

IMS2186

IMS2186 is an antichoroidal neovascularization (CNV) reagent. IMS2186 can arrest cancer cell cycle in G2/M phase, thus exerting anti-proliferation and anti-angiogenesis effects. IMS2186 has no intraocular toxicity and reduces the amount of eye leakage and diseased cells[1].

  • CAS Number: 1031206-36-6
  • MF: C18H16O4
  • MW: 296.31700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

C3d Peptide P16

C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2].

  • CAS Number: 99027-06-2
  • MF: C86H131N25O27
  • MW: 265.305
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 468.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.0±28.7 °C

Icosyl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate

Eicosyl ferulate, a phenolic compound, is isolated from the fresh root and stem of Aristolochia kankauensis. Eicosyl ferulate exhibits glucose uptake stimulatory activity[1][2].

  • CAS Number: 133882-79-8
  • MF: C30H50O4
  • MW: 474.716
  • Catalog: Metabolic Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 574.7±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 173.4±19.4 °C

N-(5,6-Dimethoxy-1,3-benzothiazol-2-yl)-N-methylglycine

N-(5,6-Dimethoxy-1,3-benzothiazol-2-yl)-N-methylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1351661-66-9
  • MF: C12H14N2O4S
  • MW: 282.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Ribulose

L-Ribulose, an isomer of L-ribose, is an important precursor for other rare sugars and L-nucleoside analogue synthesis[1].

  • CAS Number: 2042-27-5
  • MF: C5H10O5
  • MW: 150.13000
  • Catalog: Cancer
  • Density: 1.711g/cm3
  • Boiling Point: 364.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 174.1ºC

Conduritol B Epoxide (Conduritol Epoxide)

Conduritol B epoxide is an irreversible covalently bound acid β-glucosidase (GCase) inhibitor, with IC50s of 1 and 100 μM for β-glucosidase and α-glucosidase respectively.

  • CAS Number: 6090-95-5
  • MF: C6H10O5
  • MW: 162.141
  • Catalog: Neurological Disease
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 360.5±42.0 °C at 760 mmHg
  • Melting Point: 157-159ºC
  • Flash Point: 171.8±27.9 °C

2-(Pyren-1-ylaminocarbonyl)ethyl Methanethiosulfonate

2-(Pyren-1-ylaminocarbonyl)ethyl methanethiosulfonate is a fluorescent[1].

  • CAS Number: 384342-64-7
  • MF: C20H17NO3S2
  • MW: 383.48400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 171-173ºC
  • Flash Point: N/A

Golgicide A

Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1].

  • CAS Number: 1139889-93-2
  • MF: C17H14F2N2
  • MW: 284.30
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Imiglucerase

Imiglucerase (Cerezyme) is a recombinant human glucocerebrosidase, ameliorates systemic manifestations such as hepatosplenomegaly, anemia, thrombocytopenia and skeletal abnormalities in patients with type 1 (non-neuronopathic) and type 3 (chronic neuronopathic) Gaucher's disease[1].

  • CAS Number: 154248-97-2
  • MF:
  • MW:
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Versicolactone B

Versicolactone B is a sesquiterpene that can be isolated from Viola yedoensis. Versicolactone B exhibits anti-complement activity against the classical pathway and the alternative pathway[1].

  • CAS Number: 108885-62-7
  • MF: C15H20O3
  • MW: 248.32
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-Leucocyanidin

(+)-Leucocyanidin is the isoform of Leucocyanidin (HY-119580), is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models[1].

  • CAS Number: 69256-15-1
  • MF: C15H14O7
  • MW: 306.27
  • Catalog: Inflammation/Immunology
  • Density: 1.709g/cm3
  • Boiling Point: 641.5ºC at 760 mmHg
  • Melting Point: >300 °C
  • Flash Point: 341.8ºC

SK-MLCK M13

SK-MLCK M13 is a biological active peptide. (M-13 is a peptide that represents CAM-binding domain of Calmodulin (CaM) target proteins. CaM is an ubiquitous Ca2+ binding protein.)

  • CAS Number: 99268-57-2
  • MF: C134H223N43O33
  • MW: 2964.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GENZ-882706(Raceme)

GENZ-882706(Raceme) is the racemate of GENZ-882706.

  • CAS Number: 2070861-46-8
  • MF: C26H25N5O3
  • MW: 455.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sucrose stearate

Sucrose Stearate can be used as an excipient, such as Surfactants, emulsifiers, solubilizers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 25168-73-4
  • MF: C30H56O12
  • MW: 608.758
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 763.2±60.0 °C at 760 mmHg
  • Melting Point: 67-71°C (lit.)
  • Flash Point: 235.6±26.4 °C

Pyr-Gly-OH

Pyr-Gly is an inhibitory peptide. Pyr-Gly inhibits proliferation of retinal pigment epithelium (RPE) cells and fibroblasts[1].

  • CAS Number: 29227-88-1
  • MF: C7H10N2O4
  • MW: 186.17
  • Catalog: Others
  • Density: 1.405g/cm3
  • Boiling Point: 659.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 352.5ºC

IRG1-IN-1

IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases[1].

  • CAS Number: 2407652-42-8
  • MF: C18H15FO4
  • MW: 314.31
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganoderic acid G

Ganoderic acid G is a triterpene isolated from the surface part of gills of Ganoderma lucidum[1].

  • CAS Number: 98665-22-6
  • MF: C30H44O8
  • MW: 532.66600
  • Catalog: Others
  • Density: 1.27g/cm3
  • Boiling Point: 722.7ºC at 760 mmHg
  • Melting Point: 224-226 °C
  • Flash Point: 404.8ºC

Leptin (93-105), human

Leptin (93-105), human, is amino acids 93 to 105 fragment of human leptin. Leptin is a 167-residue peptide hormone mainly produced by adipocytes and acts in the central nervous system to primarily coordinate the metabolic adaptations to fasting[1][2].

  • CAS Number: 200436-43-7
  • MF: C64H110N20O23
  • MW: 1527.68000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 41335-62-0
  • MF: C15H10ClNO4S
  • MW: 335.762
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 564.7±56.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.3±31.8 °C

H-Met-Met-OH

H-Met-Met-OH (L-Methionyl-L-methionine) is a dipeptide composed of two methionine residues[1].

  • CAS Number: 7349-78-2
  • MF: C10H20N2O3S2
  • MW: 280.40700
  • Catalog: Others
  • Density: 1.237g/cm3
  • Boiling Point: 555.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 289.5ºC

ESI 09

ESI-09 is a novel noncyclic nucleotide EPAC antagonist with IC50 values of 3.2 and 1.4 μM for EPAC1 and EPAC2, respectively.

  • CAS Number: 263707-16-0
  • MF: C16H15ClN4O2
  • MW: 330.76900
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 2,6-dihydroxybenzoate

Methyl 2,6-dihydroxybenzoate is a volatile, that can be isolated from whole flowers and corolla of Primula spectabilis[1].

  • CAS Number: 2150-45-0
  • MF: C8H8O4
  • MW: 168.147
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 253.6±20.0 °C at 760 mmHg
  • Melting Point: 67-70 °C(lit.)
  • Flash Point: 101.1±15.3 °C

8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt

8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe[1].

  • CAS Number: 82962-86-5
  • MF: C17H9Na3O10S3
  • MW: 538.41200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 253-260ºC (dec.)(lit.)
  • Flash Point: N/A

PHI-27 (porcine)

PHI-27 (porcine) is a 27 amino acid peptide.PHI-27 (porcine) is used to find peptide hormones and other active peptides[1].

  • CAS Number: 80458-29-3
  • MF: C136H216N36O40
  • MW: 2995.39000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A