Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Sonnerphenolic B

Sonnerphenolic B (compound 2) is a phenolic that can be found in Sonneratia ovata[1].

  • CAS Number: 1627516-10-2
  • MF: C18H18O3
  • MW: 282.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(m-Tolylsulfonyl)-L-leucine

(m-Tolylsulfonyl)-L-leucine is a leucine derivative[1].

  • CAS Number: 1102899-58-0
  • MF: C13H19NO4S
  • MW: 285.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[D-Asn5]-Oxytocin

[D-Asn5]-Oxytocin possesses very low specific oxytocic and vasodepressor activities. By cumulative dose-response studies for oxytocic activity, [D-Asn5]-Oxytocin has similar intrinsic activity to oxytocin[1].

  • CAS Number: 5754-53-0
  • MF: C43H66N12O12S2
  • MW: 1007.19
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA (hydrochloride)

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate[1].

  • CAS Number: 1379822-04-4
  • MF: C34H53ClN10O10
  • MW: 797.299
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Laronidase

Laronidase is an enzyme for the study of mucopolysaccharide type I disease research[1].

  • CAS Number: 210589-09-6
  • MF:
  • MW:
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoasatone A

Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. Isoasatone A againsts S. litura by acting on cytochrome P450 monoxygenases and glutathione transferases[1][2].

  • CAS Number: 67451-73-4
  • MF: C24H32O8
  • MW: 448.506
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-Pro-Arg-Pro-NH2 acetate salt

H-Gly-Pro-Arg-Pro-NH2 is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. H-Gly-Pro-Arg-Pro-NH2 prevents fibrin polymerization[1].

  • CAS Number: 126047-75-4
  • MF: C18H32N8O4
  • MW: 424.49800
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tidutamab

Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells by stimulating redirected T cellmediated cytotoxicity (RTcC)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,5-Dimethyl-d6-cyclohexanone-3,4,4,5-d4

3,5-Dimethyl-d6-cyclohexanone-3,4,4,5-d4 is the deuterium labeled 3,5-Dimethylcyclohexanone[1].

  • CAS Number: 1219804-55-3
  • MF: C8H4D10O
  • MW: 136.258
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 182.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 53.8±10.7 °C

Sodium Tartrate

Sodium Tartrate is a pH-Regulating agent with antioxidant activity. Sodium Tartrate is particularly effective retarding hydrolysis while heating at high temperatures, resulting in increase of acid values (AVs) of vegetable oils[1].

  • CAS Number: 868-18-8
  • MF: C4H4Na2O6
  • MW: 194.051
  • Catalog: Others
  • Density: 1.818
  • Boiling Point: 399.3ºC at 760 mmHg
  • Melting Point: 302oFºC
  • Flash Point: 209.4ºC

5-Methylheptan-3-ol-d18

5-Methylheptan-3-ol-d18 is the deuterium labeled 5-Methylheptan-3-ol[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-(Gly)3-Lys(N3)-OH hydrochloride

H-(Gly)3-Lys(N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

  • CAS Number: 2737202-70-7
  • MF: C12H22ClN7O5
  • MW: 379.80
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Aib-OH

Fmoc-Aib-OH is an alanine derivative[1].

  • CAS Number: 94744-50-0
  • MF: C19H19NO4
  • MW: 325.358
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 544.3±33.0 °C at 760 mmHg
  • Melting Point: 182-188ºC
  • Flash Point: 283.0±25.4 °C

Hydroxyhexamide

Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.

  • CAS Number: 3168-01-2
  • MF: C15H22N2O4S
  • MW: 326.41100
  • Catalog: Cardiovascular Disease
  • Density: 1.31g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LEISHMAN'S STAIN

Leishman's stain is an essential staining tool for for staining of the peripheral blood and bone marrow smears (displayed pale bluish-grey to deep blue under oil-immersion lens)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1,3,3-Tetramethylurea-d12

1,1,3,3-Tetramethylurea-d12 is the deuterium labeled 1,1,3,3-Tetramethylurea[1].

  • CAS Number: 51219-89-7
  • MF: C5D12N2O
  • MW: 128.23600
  • Catalog: Others
  • Density: 0.946g/cm3
  • Boiling Point: 174-178ºC
  • Melting Point: 1ºC
  • Flash Point: 53.9ºC

1,1-Bis(p-chlorophenyl)methyl-carbinol

Chlorfenethol is a dehydrochlorinase inhibitor. Chlorfenethol can be used as a synergist for insecticide DDT to increase its effect on resistant strains[1].

  • CAS Number: 80-06-8
  • MF: C14H12Cl2O
  • MW: 267.15000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 69-71°C
  • Flash Point: N/A

BODIPY FL C5-HPC

BODIPY FL C5-HPC is a lipophilic green fluorescent dye (Ex/Em: 500/510 nm)[1].

  • CAS Number: 161106-88-3
  • MF: C40H67BF2N3O8P
  • MW: 797.76
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tryptamine-d2 hydrochloride

Tryptamine-d2 hydrochloride is a deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter[1].

  • CAS Number: 362049-48-7
  • MF: C10H11D2ClN2
  • MW: 198.69
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AC-ASP-TYR(SO3H)-MET-GLY-TRP-MET-NH2

CCK (26-31) (sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety[1].

  • CAS Number: 89911-65-9
  • MF: C38H50N8O13S3
  • MW: 923.04400
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

β-Casomorphin (1-4) amide (bovine) acetate salt

Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].

  • CAS Number: 74135-04-9
  • MF: C28H35N5O5
  • MW: 521.60800
  • Catalog: Cardiovascular Disease
  • Density: 1.327±0.06 g/cm3(Predicted)
  • Boiling Point: 919.9±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

BNTA

BNTA is a small molecule with extracellular matrix (ECM) modulatory properties, and it facilitates cartilage structural molecule synthesis on chondrocytes by activating superoxide dismutase 3 (SOD3). BNTA is a potential therapeutic agent in osteoarthritis[1].

  • CAS Number: 685119-25-9
  • MF: C17H11BrClNO3S2
  • MW: 456.76
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MT-VC-ZD02044

MT-VC-ZD02044 is a cytotoxic and anti-mitotic agent[1].

  • CAS Number: 1800462-96-7
  • MF: C61H101N11O17S
  • MW: 1292.58
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 5306-85-4
  • MF: C8H14O4
  • MW: 174.19
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 236.4±40.0 °C at 760 mmHg
  • Melting Point: -70°C
  • Flash Point: 108.3±0.0 °C

HER2/neu (654-662) GP2

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

  • CAS Number: 160790-21-6
  • MF: C42H77N9O11
  • MW: 884.11
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2

Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) is a substrate-specific peptide inhibitor of MLCK. Myosin light chain kinase fragment 11-19 amide inhibits hypotonicity-induced Ca2+ entry. Myosin light chain kinase fragment 11-19 amide can be used in the research of human cervical cancer[1][2].

  • CAS Number: 119386-39-9
  • MF: C40H78N18O11
  • MW: 987.16100
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ginsenoside Rk2

Ginsenoside Rk2 is a dammarane glycoside isolated from the processed ginseng (SG; Sun Ginseng)[1].

  • CAS Number: 364779-14-6
  • MF: C36H60O7
  • MW: 604.857
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 693.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 373.5±31.5 °C

1,2-Propylene-d6 carbonate

1,2-Propylene-d6 carbonate is the deuterium labeled 1,2-Propylene carbonate[1].

  • CAS Number: 202480-74-8
  • MF: C4D6O3
  • MW: 108.12600
  • Catalog: Others
  • Density: 1.239 g/cm3
  • Boiling Point: 241.699ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 135.257ºC

AA-14

AA-14 is an orphan G protein-coupled receptor GPR101 agonist that partially restores the function of the GH/IGF-1 axis[1].

  • CAS Number: 723740-38-3
  • MF: C14H12F3N3S
  • MW: 311.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TSQ

TSQ is a fluorescent sensor for cellular zinc, can image zinc proteins (λmax ~470 nm)[1].

  • CAS Number: 109628-27-5
  • MF: C17H16N2O3S
  • MW: 328.38600
  • Catalog: Others
  • Density: 1.334g/cm3
  • Boiling Point: 518.8ºC at 760mmHg
  • Melting Point: 133–134 °C (lit.)
  • Flash Point: 267.5 °C - closed cup (lit.)