Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

3-(4-Methoxy-phenyl)-1-pyrrolidin-1-yl-propenone

Piperlotine A is an alkaloid isolated from Piper lolot, with potent antiplatelet aggregation activity[1].

  • CAS Number: 389572-70-7
  • MF: C14H17NO2
  • MW: 231.290
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 436.0±24.0 °C at 760 mmHg
  • Melting Point: 117-118℃
  • Flash Point: 217.5±22.9 °C

Tigogenin

Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].

  • CAS Number: 77-60-1
  • MF: C27H44O3
  • MW: 416.637
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 516.6±20.0 °C at 760 mmHg
  • Melting Point: 202-204ºC
  • Flash Point: 266.2±21.8 °C

Clopidogrel-MP endo derivative-13C,d3

Clopidogrel-MP endo derivative-13C,d3 is the deuterium and 13C labeled Clopidogrel-MP endo derivative[1].

  • CAS Number: 1346597-76-9
  • MF: C2413CH23D3ClNO6S
  • MW: 508.006
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dibromoacetamide

2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water[1].

  • CAS Number: 598-70-9
  • MF: C2H3Br2NO
  • MW: 216.859
  • Catalog: Others
  • Density: 2.4±0.1 g/cm3
  • Boiling Point: 277.3±30.0 °C at 760 mmHg
  • Melting Point: 156°C (lit.)
  • Flash Point: 121.5±24.6 °C

1,3-Propanediol

1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism[1].

  • CAS Number: 504-63-2
  • MF: C3H8O2
  • MW: 76.094
  • Catalog: Others
  • Density: 1.052
  • Boiling Point: 214.4±0.0 °C at 760 mmHg
  • Melting Point: -32 °C
  • Flash Point: 79.4±0.0 °C

1-Methylpyrrolidine

1-Methylpyrrolidine is a methylated pyrollidine.

  • CAS Number: 120-94-5
  • MF: C5H11N
  • MW: 85.147
  • Catalog: Others
  • Density: 0.819
  • Boiling Point: 82.1±3.0 °C at 760 mmHg
  • Melting Point: -90 °C
  • Flash Point: -21.7±0.0 °C

NOTA

NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].

  • CAS Number: 56491-86-2
  • MF: C12H21N3O6
  • MW: 303.31200
  • Catalog: Cancer
  • Density: 1.321g/cm3
  • Boiling Point: 572.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.3ºC

ELA-32(human)

ELA-32(human) is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) exhibits no binding GPR15 and GPR25. ELA-32(human) activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) stimulates angiogenesis in HUVEC cells.

  • CAS Number: 1680205-79-1
  • MF: C170H289N63O39S4
  • MW: 3967.82
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-2-((S)-2-(tert-butoxycarbonylamino)-3-Methylbutanamido)propanoic acid

(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative[1].

  • CAS Number: 70396-18-8
  • MF: C13H24N2O5
  • MW: 288.34000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HHQ

2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS) that controls swarming by positively regulating phenazine production. 2-Heptyl-4-quinolone induces the production of the phenazine-1-carboxylic acid (PCA)[1].

  • CAS Number: 40522-46-1
  • MF: C16H21NO
  • MW: 243.34400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

indium(iii) isopropoxide

Indium(III) Isopropoxide is an organo-metallic compound. Indium(III) Isopropoxide uesd as a hydrogen transfer catalyst for conversion of benzylic alcohols into aldehydes or ketones via Oppenauer oxidation. Indium(III) Isopropoxide also can be used as metal precursor[1][2].

  • CAS Number: 38218-24-5
  • MF: C3H8O.1/3In
  • MW: 292.07900
  • Catalog: Others
  • Density: 0.808 g/mL at 25ºC
  • Boiling Point: 82℃
  • Melting Point: 145ºC (dec.)
  • Flash Point: 10ºC

Isomucronulatol 7-O-beta-glucoside

Isomucronulatol 7-O-glucoside is a flavonoid isolated from the roots of A. membranaceus. Isomucronulatol 7-O-glucoside exhibits weak inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflammatory effect[1].

  • CAS Number: 136087-29-1
  • MF: C23H28O10
  • MW: 464.462
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 641.5±55.0 °C at 760 mmHg
  • Melting Point: 81-82 °C
  • Flash Point: 341.8±31.5 °C

TAMRA alkyne, 6-isomer

TAMRA alkyne, 6-isomer is a linker of TAMRA which is a xanthene dye with orange emission that is commonly used for oligonucleotide labeling and amino acid sequencing. The addition of the alkyne groups allows for it to be reacted with an azide for copper-catalyzed Click Chemistry[1].

  • CAS Number: 1352649-44-5
  • MF: C28H25N3O4
  • MW: 467.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quinolinium,1-ethyl-2-[(1-ethyl-4(1H)-quinolinylidene)methyl]-, iodide (1:1)

Ethyl red (1,1'-Diethyl-2,4'-cyanine) iodide is an azo dye and acid–base indicator[1][2].

  • CAS Number: 634-21-9
  • MF: C23H23IN2
  • MW: 454.34700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 158-160ºC(lit.)
  • Flash Point: N/A

lycoclavanol

Lycoclavanol is a serratane-type triterpenoid, which can be isolated from the dried whole plants of Lycopodium japonicum[1].

  • CAS Number: 13956-51-9
  • MF: C30H50O3
  • MW: 458.72
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 566.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232.0±24.7 °C

25-Methoxyalisol A

25-O-Methylalisol A is a protostane triterpenoids isolated from Alisma orientale. The dried rhizomes of the aquatic plant Alisma orientale known as Rhizoma Alismatis is a common traditional Chinese medicine used for diuretic, anti-inflammatory, and hypolipidemic purposes, as well as the treatment of diabetes[1].

  • CAS Number: 155801-00-6
  • MF: C31H52O5
  • MW: 504.742
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 618.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.4±25.0 °C

glycyl-prolyl-glutamic acid

Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection [1][2].

  • CAS Number: 32302-76-4
  • MF: C12H19N3O6
  • MW: 301.29600
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bis(2,5-dioxopyrrolidin-1-yl) octadecanedioate

Bis(2,5-dioxopyrrolidin-1-yl) octadecanedioate is a linking reagent used in organic synthesis[1].

  • CAS Number: 191091-33-5
  • MF: C26H40N2O8
  • MW: 508.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium

1,2-Distearoyl-sn-glycero-3-phosphate-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.

  • CAS Number: 327179-02-2
  • MF: C39H6D70NaO8P
  • MW: 797.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Lys(Z)-Osu

Z-Lys(Z)-OSu is a lysine derivative[1].

  • CAS Number: 21160-83-8
  • MF: C26H29N3O8
  • MW: 511.524
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Chloro-4-methoxybenzene-d4

1-Chloro-4-methoxybenzene-d4 is the deuterium labeled 1-Chloro-4-methoxybenzene[1].

  • CAS Number: 1219804-86-0
  • MF: C7H7ClO
  • MW: 142.583
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 184.4±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 78.3±0.0 °C

GF 15

GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.

  • CAS Number: 888042-13-5
  • MF: C23H21ClO6
  • MW: 428.86
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methylpyrazole

3-Methylpyrazole is used as a nitrification inhibitor of nitrification in soil[1].

  • CAS Number: 1453-58-3
  • MF: C4H6N2
  • MW: 82.104
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 204.0±0.0 °C at 760 mmHg
  • Melting Point: 36 - 37ºC
  • Flash Point: 87.4±11.7 °C

α-Cyanopyridine-d4

α-Cyanopyridine-d4 is the deuterium labeled α-Cyanopyridine[1].

  • CAS Number: 1219795-17-1
  • MF: C6H4N2
  • MW: 104.109
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 225.5±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 89.4±0.0 °C

Carbaryl-(methyl-d3)

Carbaryl-d3 is the deuterium labeled N6-(carboxymethyl)-L-lysine[1].

  • CAS Number: 1433961-56-8
  • MF: C12H8D3NO2
  • MW: 204.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite

2'-O-MOE-5-Me-C (Bz) is a nucleotide for the stereoselective synthesis of nucleoside alkyl phosphonates[1].

  • CAS Number: 163759-94-2
  • MF: C47H54N5O9P
  • MW: 863.933
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Aminopurine

2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2].

  • CAS Number: 452-06-2
  • MF: C5H5N5
  • MW: 135.127
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 328.2±25.0 °C at 760 mmHg
  • Melting Point: 280-282 °C(lit.)
  • Flash Point: 152.3±23.2 °C

Fluorobenzene

Fluorobenzene-d5 is the deuterium labeled Fluorobenzene-d5[1].

  • CAS Number: 1423-10-5
  • MF: C6D5F
  • MW: 96.102
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 84.7±9.0 °C at 760 mmHg
  • Melting Point: -42ºC
  • Flash Point: -12.8±0.0 °C

Thioredoxin reductase peptide

Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].

  • CAS Number: 950890-23-0
  • MF: C66H106N18O18S2
  • MW: 1503.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

YM-264

YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes.

  • CAS Number: 131888-54-5
  • MF: C28H36N4O5S
  • MW: 540.67400
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: 629.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 334.6ºC