Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity[1].
Anpocogin is the Ancyclostoma canium nematode anticoagulant protein c2, variant (C-terminal P85 added). Anpocogin, produced in Pichia pastoris, serves as an anticoagulant agent[1].
Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice[1].
Echinosporin (XK-213) is an antibiotic. Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity[1][2].
Fmoc-Phe-OH-15N is a 15N-labeled Propoxur.
Strictosamide has important effects on inflammation and inflammatory pain. Strictosamide possesses antiplasmodial and antifungal activities[1].
Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans)[1][1][3].
Propoxur is a carbamate insecticide with a fast knockdown and long residual effect used against turf, forestry, and household pests and fleas.
alpha-Mangostin-d3 (α-Mangostin-d3) is the deuterium labeled alpha-Mangostin. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM[1][2][3].
Vincetoxicoside B, isolated from Polygonum paleaceum Wall, shows antifungal activity[1].
Antifungal agent 73 (compound A32) is an antifungal agent for azole-resistant candidiasis. Antifungal agent 73 disrupts the fungal cell wall and cell membrane. Antifungal agent 73 shows potent in vivo antifungal activity against pathogenic fungi and fluconazole-resistant strains[1].
Benzoic acid-d5 is a deuterium substitute for Benzoic acid. Benzoic acid is an aromatic alcohol that occurs naturally in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid can act as a preservative by inhibiting bacteria and fungi[1][2].
2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].
Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].
Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L[1]. Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons[2].
Pydiflumetofen is a new generation of succinate dehydrogenase inhibitor fungicide[1].
Sertaconazole (FI7056 free base) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells[1][2][3][4].
Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity[1][2].
Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component[1].
Phenazine-1-carboxylic acid exhibits strong antifungal activity against phytopathogenic fungi.
Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis sp[1].
4-Methylcinnamic acid, a Cinnamic acid analog, can be used as a intervention catalyst for overcoming antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents[1].
Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO)[1].
Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC50 = 1 nM for T. rubrum)[1].
Ciclopirox olamine is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor.
trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity[1][2].
Averantin is the minor metabolite of the fungus Cercospora arachidicola[1]. Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway[2].
Methyl 3,4-dimethoxycinnamate is an inhibitor of uredospore germination. Methyl 3,4-dimethoxycinnamate also inhibits global DNA methylation in in Hep3B cells[1][2].