Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

NCX 1000

NCX 1000 is a liver-specific NO donor compound derived from ursodeoxycholic acid (UDCA).

  • CAS Number: 401519-96-8
  • MF: C38H55NO10
  • MW: 685.844
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 758.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 412.4±32.9 °C

2-Methoxynaphthalene-d7

2-Methoxynaphthalene-d7 is the deuterium labeled 2-Methoxynaphthalene[1].

  • CAS Number: 1219795-25-1
  • MF: C11H10O
  • MW: 158.197
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 272.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 102.3±8.0 °C

Metopimazine

Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) [1].

  • CAS Number: 14008-44-7
  • MF: C22H27N3O3S2
  • MW: 445.598
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 679.0±65.0 °C at 760 mmHg
  • Melting Point: 170.5℃
  • Flash Point: 364.4±34.3 °C
  • CAS Number: 415684-38-7
  • MF: C62H93N19O23
  • MW: 1472.515
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bis(8-methylnonyl) 1,2-(2H4)benzenedicarboxylate

Bis(8-methyl-1-nonyl) Phthalate-3,4,5,6-d4 is the deuterium labeled Bis(8-methyl-1-nonyl) Phthalate[1].

  • CAS Number: 1346604-79-2
  • MF: C28H42D4O4
  • MW: 450.687
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 425.8±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 227.6±9.3 °C

α-Amyrin palmitate

α-Amyrin palmitate is isolated from Santalum album (sandalwood). α-Amyrin palmitate can be used for the study of arthritis in vivo[1].

  • CAS Number: 22255-10-3
  • MF: C46H80O2
  • MW: 665.126
  • Catalog: Inflammation/Immunology
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 663.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.6±19.0 °C

Ammonium Chloride, 99.5-100.5%, PT

Ammonium chloride-d4 is the deuterium labeled Ammonium chloride[1].

  • CAS Number: 12015-14-4
  • MF: ClD4N
  • MW: 57.51610
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 340ºC (subl.)(lit.)
  • Flash Point: N/A

11α,12α-Oxidotaraxerol palMitate

3β-Hydroxy-11,12-epoxy–friedoolean-14-enyl palmitate is a fatty acids esterified with triterpenes[1].

  • CAS Number: 495389-95-2
  • MF: C46H78O3
  • MW: 679.11
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 673.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 298.5±26.1 °C

Endoxifen (hydrochloride)

Endoxifen hydrochloride, the active metabolite of Tamoxifen, is a potent antiestrogen that targets estrogen receptor.

  • CAS Number: 1197194-41-4
  • MF: C25H28ClNO2
  • MW: 409.948
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Semastatin 5A.2

Semastatin 5A.2 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs[1].

  • CAS Number: 929555-16-8
  • MF: C87H135N29O26S3
  • MW: 2099.38
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Indo-1 AM

Indo-1 AM is a fluorescent Ca2+ indicator (λex=340 nm, λem=405/485 nm).

  • CAS Number: 112926-02-0
  • MF: C47H51N3O22
  • MW: 1009.91000
  • Catalog: Dye Reagents
  • Density: 1.374g/cm3
  • Boiling Point: 1009.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 564.1ºC

Quercetin 3-O-malonylglucoside

Quercetin 3-O-(6''-O-malonyl)-β-D-glucoside, a natural flavonol glycoside, possesses antioxidant activity[1].

  • CAS Number: 96862-01-0
  • MF: C24H22O15
  • MW: 550.42200
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 195-201 °C
  • Flash Point: N/A

PF-10040

PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].

  • CAS Number: 132928-46-2
  • MF: C20H24ClNO2
  • MW: 345.86300
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: 446.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 179.9ºC

Melibiose

D-Melibiose is a disaccharide which is composed of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.

  • CAS Number: 585-99-9
  • MF: C12H22O11
  • MW: 342.297
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 662.8±55.0 °C at 760 mmHg
  • Melting Point: 182ºC (dec.)(lit.)
  • Flash Point: 354.6±31.5 °C

LIPASE SUBSTRATE CHROMOGENIC

Lipase Substrate is a substrate of lipase to detect activity[1].

  • CAS Number: 195833-46-6
  • MF: C45H69NO8
  • MW: 752.031
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 792.2±60.0 °C at 760 mmHg
  • Melting Point: 29 - 31°C (lit.)
  • Flash Point: 151.3±27.3 °C

Pyrimethanil-d5

Pyrimethanil-d5 is the deuterium labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

  • CAS Number: 2118244-83-8
  • MF: C12H8D5N3
  • MW: 204.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Bromo-L-Phe-OH

2-Amino-3-(4-bromophenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 14091-15-7
  • MF: C9H10BrNO2
  • MW: 244.085
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 368.4±32.0 °C at 760 mmHg
  • Melting Point: 262-263 °C (dec.)(lit.)
  • Flash Point: 176.6±25.1 °C

DL-Dithiothreitol

DTT is a small-molecule redox reagent.

  • CAS Number: 3483-12-3
  • MF: C4H10O2S2
  • MW: 154.251
  • Catalog: Biochemical Assay Reagents
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 364.5±42.0 °C at 760 mmHg
  • Melting Point: 38-43ºC
  • Flash Point: 174.2±27.9 °C

Acetyl-Hirudin (55-65) (sulfated)

Acetyl-Hirudin (55-65) (sulfated) is a biologically active peptide.

  • CAS Number: 125441-01-2
  • MF: C66H92N12O28S
  • MW: 1533.565
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pGlu-Pro-Arg-MNA

pGlu-Pro-Arg-MNA is a chromogenic substrate. Sequence: pGlu-Pro-Arg-MNA.

  • CAS Number: 130835-45-9
  • MF: C23H32N8O7
  • MW: 532.55
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Cha-OH

Fmoc-Cha-OH is an alanine derivative[1].

  • CAS Number: 135673-97-1
  • MF: C24H27NO4
  • MW: 393.475
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 610.5±38.0 °C at 760 mmHg
  • Melting Point: 140 °C
  • Flash Point: 323.0±26.8 °C

Tectorigenin

Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth.

  • CAS Number: 548-77-6
  • MF: C16H12O6
  • MW: 300.263
  • Catalog: Inflammation/Immunology
  • Density: 1.512
  • Boiling Point: 601.5±55.0 °C at 760 mmHg
  • Melting Point: 225-226°
  • Flash Point: 230.1±25.0 °C

Polyporoid B

Polyporoid B is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo[1].

  • CAS Number: 1042362-45-7
  • MF: C28H44O7
  • MW: 492.64
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Erigeside I

Erigeside I is a free radical scavenger isolated from Erigeron breviscapus[1].

  • CAS Number: 224824-74-2
  • MF: C20H20O11
  • MW: 436.366
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 807.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.5±27.8 °C

Velaglucerase alfa

Velaglucerase alfa is produced through gene activation technology and is identical to wild-type enzyme. Velaglucerase alfa targets accumulated glucocerebroside primarily within the lysosome of the macrophages in the affected organs and systems. Velaglucerase alfa is an enzyme replacement therapy (ERT) for type 1 Gaucher disease (GD)[1].

  • CAS Number: 884604-91-5
  • MF:
  • MW:
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DL-Panthenol

DL-Panthenol is an intermediate of organic synthesis.

  • CAS Number: 16485-10-2
  • MF: C9H19NO4
  • MW: 205.251
  • Catalog: Biochemical Assay Reagents
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 483.6±45.0 °C at 760 mmHg
  • Melting Point: 66-69 °C(lit.)
  • Flash Point: 246.3±28.7 °C

DIBAC-GGFG-NH2CH2-Dxd

DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-drug conjugates[1].

  • CAS Number: 2758875-01-1
  • MF: C61H58FN9O12
  • MW: 1128.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sulfo-Cyanine5.5 NHS ester tripotassium

Sulfo-Cyanine5.5 NHS ester tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging[1].

  • CAS Number: 2419286-92-1
  • MF: C44H42K3N3O16S4
  • MW: 1114.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hyponine E

Hyponine E, a macrocyclic sesquiterpene pyridine alkaloid that could be isolated from from Tripterygium hypoglaucum, possesses anti-inflammatory effects[1][2].

  • CAS Number: 226975-99-1
  • MF: C45H48N2O19
  • MW: 920.865
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 913.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 506.1±34.3 °C

angelol G

Angelol G, a coumarin, can be isolated from Campylotropis hirtella. Angelol G shows inhibitory activity for prostate specific antigen (PSA)IC50 value of 152.1μM. Angelol G can be used for the research of benign prostate hyperplasia (BPH)[1].

  • CAS Number: 83199-38-6
  • MF: C20H24O7
  • MW: 376.40000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A