Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide.
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction.
Sinensin is a natural product, that can be isolated from the roots of Cudrania cochinchinensis[1].
Coumarin 334 (Coumarin 521) is a laser dye with rigid structure[1].
D-Pantothenic acid(pantothenate) is a water-soluble vitamin and an essential nutrient for for many animals.Target: OthersPantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient. Animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. From Wikipedia.
1β-Hydroxybaccatin I (1-Hydroxybaccatin I) can be extracted from Taxus wallichiana[1].
1-Bromodecane-d5 is the deuterium labeled 1-Bromodecane[1].
Fmoc-D-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative[1].
Anthraquinone-2-carboxylic acid is a major anthraquinone isolated from Brazilian taheebo, with anti-inflammatory activity and antinociceptive[1].
6-AcMorhap (C3 hapten) is a 6-O-acetyl-morphine derivative. 6-AcMorhap contains an amino group in position C3 and this group is acylated with β-mercaptopropionic acid[1].
Puromycin-bis(PEG2-amide)-Biotin is used for single-cell translatome sequencing[1].
Vitamin B15 (Pangamic Acid) hemicalcium is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 hemicalcium contains D-gluconodimethyl amino acetic acid. Vitamin B15 hemicalcium is also a immune-correcting agent[1][2]. Vitamin B15 hemicalcium can be used for wide range of diseases.
Fmoc-Tyr(tBu)-OH is a tyrosine derivative[1].
Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias.IC50 value:Target: A natural product for anti-cardiac arrhythmiasIn vitro: Lappaconitine hydrobromide was found to exert an inhibitory effect on inward tetrodotoxin-sensitive sodium currents without changing their voltage dependence [1]. In vivo: The effect of Lappaconitine hydrobromide on aconitine--induced arrhythmias is due to modulation of genes encoding Na(+)-, K(+)-, Ca(2+)-channels, conducting ionic currents (I(Na), I(to), I(Ks), I(K1), I(CaT)), which are involved in the formation of different phases of the action potential [2]. Lappaconitine hydrobromide was found to be beneficial both in ventricular and supraventricular premature beats. Oral allapinine usually showed its effect 40-60 minutes following its administration, its maximum action being 4-5 hours later, its duration was some 8 hours. The optimal dose of the drug amounted to 75 mg/day [3].
Phosphoenolpyruvic acid tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group, penetrates the cell membrane and exhibits cytoprotective and anti-oxidative activity[1].
SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble drugs.
For-Met-Leu-pNA is an N-formylated peptide substrate that can be used in the deformylase assays[1].
Monocrotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant to induce pulmonary hypertension in rodents.
NH2-AKA-COOH is a oligopeptide compoused of Ala-Lys-Ala.
2-Amino-8-oxononanoic acid is an amino acid, incorporation into proteins in E.coli in genetic. 2-Amino-8-oxononanoic acid is efficient in labeling of proteins with different probes with a site-specific manner under a mild condition close to the physiological pH[1].
2-(2-Aminopropanamido)pentanoic acid is a valine derivative[1].
4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].
Propyl pyrazole triol (PPT) is an estrogen receptor alpha (ERσ) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%)[1].
Antipyrine is an analgesic and antipyretic agent.Target: OthersAntipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine was one of the first important synthetic drugs. antipyrine went into widespread clinical use as an antipyretic the same year it was synthesized. Two years after its introduction, reports began to appear of its analgesic effects and in the succeeding years, as the use of antipyrine as an antipyretic declined, it gained considerable popularity as an analgesic. The plasma halflife of antipyrine is significantly longer and the clearance significantly lower in the elderly group. This finding of an impaired metabolism of antipyrine in the elderly has since been confirmed in a much larger study and subsequently other drugs have been shown to be metabolized more slowly in this age group [1].
β-Methyl L-aspartate hydrochloride is an aspartic acid derivative[1].
Baccatin is a compound isolated from the roots of Sapium Sebiferum[1].
L-carnitine: CLO4, 3-hydroxyisovaleryl-d3 is the deuterium labeled L-carnitine: CLO4, 3-hydroxyisovaleryl[1].
Isosaxalin is a natural product isolated from Murraya koeningii[1].
PZ-2891 is an oral, allosteric, and brain penetrant pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA.
Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal[1][2].